YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: YLR072W
Organism: Saccharomyces cerevisiae
Length: 693 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR072W.

Description E-value Query
Range
Subject
Range
LAM6_YEAST - Membrane-anchored lipid-binding protein LAM6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
YLR072W - Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytopla...
0.0 [1..693] [1..693]
gi|26665873, gi|... - gi|26665873|ref|NP_082174.2| GRAM domain containing 1A [Mus musculus], gi|17391321|gb|AAH18554.1| Gr...
0.0 [158..652] [11..556]
gi|24308247, gi|... - gi|24308247|ref|NP_065946.1| hypothetical protein LOC57655 [Homo sapiens], gi|15559417|gb|AAH14077.1...
0.0 [156..652] [9..559]
SPBC20F10.07 - GRAM domain protein
YGZ7_SCHPO - Uncharacterized membrane protein C20F10.07 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN...
0.0 [112..571] [149..593]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-93 [100..533] [109..540]

Back

Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWGDSMRELG DAMDNELNAV KPVVEEGGMD GARKFIKGKS FQKSSTEHML ISPGRDGSVP  60
   61 LNGLKSSPAD PHLSDVNSIL DNHRGGGETA LTSVNNIIMA TSTNGDSDGV DG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.290 a.118.8 TPR-like
View Download 0.310 a.77.1 DEATH domain
View Download 0.243 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.248 a.24.17 Group V grass pollen allergen
View Download 0.238 a.118.8 TPR-like
View Download 0.235 c.3.1 FAD/NAD(P)-binding domain
View Download 0.213 a.24.17 Group V grass pollen allergen

Predicted Domain #2
Region A:
Residues: [113-275]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAKRPSISNC SSRSSFFDTV LSTFSLKSNS QDTVTNEVKN IEVQFASEEA NKKFRQMFKP  60
   61 LAPNTRLITD YFCYFHREFP YQGRIYLSNT HLCFNSTVLN WMAKLQIPLN EIKYLDKVTT 120
  121 NSSAISVETV TNRYTFSGFI ARDEVFQLIT RVWSKENLTN IND

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 28.142668
Match: PF02893
Description: GRAM domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.37262912917599 bayes_pls_golite062009
protein binding 1.01923599216718 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [276-353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VLEVDERVSK KKGISSTPSS IFNNVSTNAY NDFISTTTTE PTSRASYMSE NDMLIEEAIR  60
   61 SVDDYMGTPR ASPSSSSS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.648 a.4.1 Homeodomain-like
View Download 0.629 a.144.1 PABC (PABP) domain
View Download 0.578 a.156.1 S13-like H2TH domain
View Download 0.557 a.144.1 PABC (PABP) domain
View Download 0.511 a.4.5 "Winged helix" DNA-binding domain
View Download 0.476 a.144.2 Ribosomal protein L20
View Download 0.474 a.4.5 "Winged helix" DNA-binding domain
View Download 0.415 b.34.8 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
View Download 0.363 a.39.1 EF-hand
View Download 0.350 a.7.7 BAG domain
View Download 0.349 a.4.5 "Winged helix" DNA-binding domain
View Download 0.344 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.335 a.64.1 Saposin
View Download 0.304 a.3.1 Cytochrome c
View Download 0.302 a.156.1 S13-like H2TH domain
View Download 0.297 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.297 a.61.1 Retroviral matrix proteins
View Download 0.294 a.64.2 Bacteriocin AS-48
View Download 0.293 a.65.1 Annexin
View Download 0.285 a.60.8 HRDC-like
View Download 0.272 a.156.1 S13-like H2TH domain
View Download 0.269 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.258 a.118.1 ARM repeat
View Download 0.253 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.245 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.240 a.156.1 S13-like H2TH domain
View Download 0.237 a.50.1 Anaphylotoxins (complement system)
View Download 0.235 a.118.14 FliG
View Download 0.234 a.4.5 "Winged helix" DNA-binding domain
View Download 0.232 a.77.1 DEATH domain
View Download 0.230 a.60.3 C-terminal domain of RNA polymerase alpha subunit
View Download 0.226 d.34.1 DNA-binding domain of Mlu1-box binding protein MBP1
View Download 0.226 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.214 d.26.1 FKBP-like
View Download 0.214 a.64.1 Saposin
View Download 0.213 d.15.1 Ubiquitin-like
View Download 0.210 a.144.1 PABC (PABP) domain
View Download 0.204 d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.203 d.48.1 RecA protein, C-terminal domain

Predicted Domain #4
Region A:
Residues: [354-588]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSSSSSLGS STTYYCRPVY RLKPNAPFQY EGPFHVQETM DFPYKPEANN EYVLLERQFS  60
   61 VPPGLLFIMM FNEDNPVFEL SFLKTQDSSN ISHIGTFEKV NKDGQHYREF QYTKQLHFPV 120
  121 GPKSTNCEVA EILLHCDWER YINVLSITRT PNVPSGTSFS TRTRYMFRWD DQGQGCILKI 180
  181 SFWVDWNASS WIKPMVESNC KNGQISATKD LVKLVEEFVE KYVELSKEKA DTLKP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.240804061374211 bayes_pls_golite062009
catalytic activity 0.0521786759115963 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [589-693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPSVTSFGSP RKVAAPELTM VQPESKPEAE AEISEIGSDR WRFNWVNIII LVLLVLNLLY  60
   61 LMKLNKKMDK LTNLMTHKDE VVAHATLLDI PAKVQWSRPR RGDVL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.807 0.886 cytoplasm a.1.1 Globin-like
View Download 0.529 0.886 cytoplasm a.22.1 Histone-fold
View Download 0.461 0.886 cytoplasm a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.807 0.886 cytoplasm a.1.1 Globin-like
View Download 0.529 0.886 cytoplasm a.22.1 Histone-fold
View Download 0.462 0.886 cytoplasm a.22.1 Histone-fold
View Download 0.461 0.886 cytoplasm a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.409 0.886 cytoplasm a.22.1 Histone-fold
View Download 0.353 0.886 cytoplasm a.1.1 Globin-like
View Download 0.346 0.886 cytoplasm a.24.3 Cytochromes
View Download 0.346 0.886 cytoplasm a.29.2 Bromodomain
View Download 0.338 0.886 cytoplasm a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.332 0.886 cytoplasm f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.327 0.886 cytoplasm a.29.2 Bromodomain
View Download 0.316 0.886 cytoplasm a.118.1 ARM repeat
View Download 0.308 0.886 cytoplasm a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.300 0.886 cytoplasm a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.299 0.886 cytoplasm f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.288 0.886 cytoplasm a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.282 0.886 cytoplasm c.98.2 HPr kinase/phoshatase HprK N-terminal domain
View Download 0.279 0.886 cytoplasm a.118.11 Cytochrome c oxidase subunit E
View Download 0.278 0.886 cytoplasm d.95.2 Homing endonucleases
View Download 0.277 0.886 cytoplasm a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.276 0.886 cytoplasm a.47.2 t-snare proteins
View Download 0.273 0.886 cytoplasm a.7.8 GAT domain
View Download 0.266 0.886 cytoplasm a.2.3 Chaperone J-domain
View Download 0.262 0.886 cytoplasm a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.261 0.886 cytoplasm f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.253 0.886 cytoplasm a.29.4 RecG, N-terminal domain
View Download 0.251 0.886 cytoplasm a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.251 0.886 cytoplasm a.7.1 Spectrin repeat
View Download 0.242 0.886 cytoplasm a.74.1 Cyclin-like
View Download 0.241 0.886 cytoplasm a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.238 0.886 cytoplasm a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.236 0.886 cytoplasm a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.230 0.886 cytoplasm a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.227 0.886 cytoplasm a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.218 0.886 cytoplasm a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.212 0.886 cytoplasm a.118.1 ARM repeat
View Download 0.211 0.886 cytoplasm a.4.1 Homeodomain-like
View Download 0.209 0.886 cytoplasm a.74.1 Cyclin-like
View Download 0.208 0.886 cytoplasm a.59.1 PAH2 domain
View Download 0.200 0.886 cytoplasm a.39.1 EF-hand
View Download 0.200 0.886 cytoplasm f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle