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View Structure Prediction Details

Protein: SSK1
Organism: Saccharomyces cerevisiae
Length: 712 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSK1.

Description E-value Query
Range
Subject
Range
gi|151941174 - gi|151941174|gb|EDN59552.1| two-component signal transducer that with Sln1p regulates osmosensing MA...
SSK1_YEAST - Osmolarity two-component system protein SSK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
SSK1 - Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing ...
0.0 [1..712] [1..712]
gi|17646113 - gi|17646113|gb|AAL40901.1|AF145972_1 ethylene receptor [Petunia x hybrida]
0.0 [225..655] [318..738]
gi|18252319 - gi|18252319|gb|AAL66191.1|AF386509_1 putative ethylene receptor [Pyrus communis]
0.0 [234..652] [333..737]
ETR1_PRUPE - Ethylene receptor OS=Prunus persica GN=ETR1 PE=2 SV=1
0.0 [225..652] [320..734]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [225..655] [334..754]
gi|25365089, gi|... - gi|2852991|gb|AAC02213.1| ethylene receptor homolog [Lycopersicon esculentum], pir||T52288 ethylene ...
0.0 [225..655] [334..754]
gi|15131529 - gi|15131529|emb|CAC48384.1| ethylene receptor [Fragaria x ananassa]
0.0 [225..652] [320..737]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNSALLWKV WLRIDNSTDE VNQPIAVQFD EIDTVDDLKS RFFQKLSSTR WREINDNASI  60
   61 AIGLYAPKFD NQADNTSSNN TNDNSCRSKS NGAGSGANLS VNSNTKSSVS PTAGSFGLSK 120
  121 DLAKDRNVLQ HPKPTQKRGA LYDAFAAVPT VAATTNVDFP PNEAPMLSPQ RPYSTSPKQF 180
  181 PAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKSPLLRFAS VSPYPKFHSD NQIMASAGLT YVSPHNKNKY TRPLIRKGLN FTTESVNDCT  60
   61 YKIIFEPDEL AINIYKELFG TMGSQPASQP LLIFSNVNLR QDVPPLDILN VVDYVPTNEE 120
  121 ISQQKTQPTD H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [315-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAVGVFHLDD HISPGEQGLK QTIGDKADLK GKDGNSSPQE FKLITDEEQL RRASQELKDE  60
   61 EKDAESPWQA ILLLPKGYKG GVDFRNKPVA HTDSSFNNED TITHSELEVN TGSPSQESGS 120
  121 LNEAGIGITQ PMSEVQRRKE DVTPASPILT SSQTPHYSNS LYNAPFAVSS PPDPLPNLFT 180
  181 TTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1bxdA_
Description: Histidine kinase domain of the osmosensor EnvZ
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [498-712]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKVFPKINVL IVEDNVINQA ILGSFLRKHK ISYKLAKNGQ EAVNIWKEGG LHLIFMDLQL  60
   61 PVLSGIEAAK QIRDFEKQNG IGIQKSLNNS HSNLEKGTSK RFSQAPVIIV ALTASNSQMD 120
  121 KRKALLSGCN DYLTKPVNLH WLSKKITEWG CMQALIDFDS WKQGESRMTD SVLVKSPQKP 180
  181 IAPSNPHSFK QATSMTPTHS PVRKNSNLSP TQIEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 1kgsA_
Description: PhoB; PhoB receiver domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle