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View Structure Prediction Details

Protein: SSK1
Organism: Saccharomyces cerevisiae
Length: 712 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSK1.

Description E-value Query
Range
Subject
Range
gi|151941174 - gi|151941174|gb|EDN59552.1| two-component signal transducer that with Sln1p regulates osmosensing MA...
SSK1_YEAST - Osmolarity two-component system protein SSK1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
SSK1 - Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing ...
0.0 [1..712] [1..712]
gi|17646113 - gi|17646113|gb|AAL40901.1|AF145972_1 ethylene receptor [Petunia x hybrida]
0.0 [225..655] [318..738]
gi|18252319 - gi|18252319|gb|AAL66191.1|AF386509_1 putative ethylene receptor [Pyrus communis]
0.0 [234..652] [333..737]
ETR1_PRUPE - Ethylene receptor OS=Prunus persica GN=ETR1 PE=2 SV=1
0.0 [225..652] [320..734]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [225..655] [334..754]
gi|25365089, gi|... - gi|2852991|gb|AAC02213.1| ethylene receptor homolog [Lycopersicon esculentum], pir||T52288 ethylene ...
0.0 [225..655] [334..754]
gi|15131529 - gi|15131529|emb|CAC48384.1| ethylene receptor [Fragaria x ananassa]
0.0 [225..652] [320..737]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNSALLWKV WLRIDNSTDE VNQPIAVQFD EIDTVDDLKS RFFQKLSSTR WREINDNASI  60
   61 AIGLYAPKFD NQADNTSSNN TNDNSCRSKS NGAGSGANLS VNSNTKSSVS PTAGSFGLSK 120
  121 DLAKDRNVLQ HPKPTQKRGA LYDAFAAVPT VAATTNVDFP PNEAPMLSPQ RPYSTSPKQF 180
  181 PAT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-314]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKSPLLRFAS VSPYPKFHSD NQIMASAGLT YVSPHNKNKY TRPLIRKGLN FTTESVNDCT  60
   61 YKIIFEPDEL AINIYKELFG TMGSQPASQP LLIFSNVNLR QDVPPLDILN VVDYVPTNEE 120
  121 ISQQKTQPTD H

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.428 0.081 osmosensory signaling pathway via two-component system d.95.2 Homing endonucleases
View Download 0.416 0.039 osmosensory signaling pathway via two-component system a.158.1 F-box domain
View Download 0.381 0.027 osmosensory signaling pathway via two-component system d.77.1 Ribosomal protein L5
View Download 0.357 0.008 osmosensory signaling pathway via two-component system d.228.1 Replication modulator SeqA, C-terminal DNA-binding domain
View Download 0.397 N/A N/A d.224.1 SufE-like
View Download 0.341 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.318 N/A N/A d.58.7 RNA-binding domain, RBD
View Download 0.312 N/A N/A c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.284 N/A N/A a.118.8 TPR-like
View Download 0.269 N/A N/A d.95.2 Homing endonucleases
View Download 0.266 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.264 N/A N/A a.60.1 SAM/Pointed domain
View Download 0.255 N/A N/A a.40.2 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain
View Download 0.241 N/A N/A d.58.1 4Fe-4S ferredoxins
View Download 0.217 N/A N/A a.1.1 Globin-like
View Download 0.211 N/A N/A a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.203 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.201 N/A N/A a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #3
Region A:
Residues: [315-497]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAVGVFHLDD HISPGEQGLK QTIGDKADLK GKDGNSSPQE FKLITDEEQL RRASQELKDE  60
   61 EKDAESPWQA ILLLPKGYKG GVDFRNKPVA HTDSSFNNED TITHSELEVN TGSPSQESGS 120
  121 LNEAGIGITQ PMSEVQRRKE DVTPASPILT SSQTPHYSNS LYNAPFAVSS PPDPLPNLFT 180
  181 TTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1bxdA_
Description: Histidine kinase domain of the osmosensor EnvZ
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [498-712]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKVFPKINVL IVEDNVINQA ILGSFLRKHK ISYKLAKNGQ EAVNIWKEGG LHLIFMDLQL  60
   61 PVLSGIEAAK QIRDFEKQNG IGIQKSLNNS HSNLEKGTSK RFSQAPVIIV ALTASNSQMD 120
  121 KRKALLSGCN DYLTKPVNLH WLSKKITEWG CMQALIDFDS WKQGESRMTD SVLVKSPQKP 180
  181 IAPSNPHSFK QATSMTPTHS PVRKNSNLSP TQIEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 41.522879
Match: 1kgsA_
Description: PhoB; PhoB receiver domain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle