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View Structure Prediction Details

Protein: SSL1
Organism: Saccharomyces cerevisiae
Length: 461 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSL1.

Description E-value Query
Range
Subject
Range
SSL1_YEAST - Suppressor of stem-loop protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSL1 P...
gi|190406046 - gi|190406046|gb|EDV09313.1| suppressor of stem-loop protein 1 [Saccharomyces cerevisiae RM11-1a]
SSL1 - Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kina...
0.0 [1..461] [1..461]
ssl1 - transcription factor TFIIH complex subunit Ssl1
TFH47_SCHPO - TFIIH basal transcription factor complex p47 subunit OS=Schizosaccharomyces pombe (strain 972 / ATCC...
0.0 [39..455] [3..417]
gi|3327882 - gi|3327882|dbj|BAA31745.1| SSL1 [Schizosaccharomyces pombe]
0.0 [68..455] [2..388]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [67..457] [2..388]
gi|208968221, gi... - gi|208968221|dbj|BAG73949.1| General transcription factor IIH subunit 2 [synthetic construct], gi|14...
GTF2H2 - general transcription factor IIH, polypeptide 2, 44kDa
0.0 [67..457] [2..388]
gi|148668487, gi... - gi|16740713|gb|AAH16231.1| Gtf2h2 protein [Mus musculus], gi|148668487|gb|EDL00806.1| general transc...
0.0 [67..457] [2..389]
FBpp0304361, Ssl1-PA - The gene Ssl1 is referred to in FlyBase by the symbol Dmel\Ssl1 (CG11115, FBgn0037202). It is a prot...
gi|220952514, gi... - gi|220952514|gb|ACL88800.1| Ssl1-PA [synthetic construct], gi|220945098|gb|ACL85092.1| Ssl1-PA [synt...
0.0 [66..458] [4..407]

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Predicted Domain #1
Region A:
Residues: [1-116]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPVVISESE EDEDRVAITR RTKRQVHFDG EGDDRVDQQQ QQHSSSHRDR DKHVQRKKKK  60
   61 RLSNRNLQGS NGGYAWEDEI KRSWDLVKVD DEGDMASLVA SIVEARKKRT AKKNIT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.413 d.20.1 UBC-like
View Download 0.380 d.110.4 SNARE-like
View Download 0.397 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.557 a.24.17 Group V grass pollen allergen
View Download 0.375 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.361 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.307 a.29.2 Bromodomain
View Download 0.306 d.79.3 L30e-like
View Download 0.302 a.24.11 Bacterial GAP domain
View Download 0.300 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.290 a.158.1 F-box domain
View Download 0.282 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.274 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.262 a.29.2 Bromodomain
View Download 0.259 c.54.1 IIA domain of mannose transporter, IIA-Man
View Download 0.255 f.18.1 F1F0 ATP synthase subunit A
View Download 0.240 a.29.4 RecG, N-terminal domain
View Download 0.236 d.20.1 UBC-like
View Download 0.220 d.146.1 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
View Download 0.207 b.1.8 Cu,Zn superoxide dismutase-like
View Download 0.206 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.202 a.1.1 Globin-like

Predicted functions:

Term Confidence Notes
binding 2.75824485094584 bayes_pls_golite062009
nucleic acid binding 2.08531850924748 bayes_pls_golite062009
DNA binding 1.91667917801679 bayes_pls_golite062009
protein binding 1.53311876872122 bayes_pls_golite062009
protein complex binding 0.68878168136573 bayes_pls_golite062009
hydrolase activity 0.564965244474085 bayes_pls_golite062009
structure-specific DNA binding 0.450760554291027 bayes_pls_golite062009
protein dimerization activity 0.4223194470523 bayes_pls_golite062009
protein heterodimerization activity 0.32921284315242 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [117-345]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYQRGIIRSL ILTLDCSEAM LEKDLRPNRH AMIIQYAIDF VHEFFDQNPI SQMGIIIMRN  60
   61 GLAQLVSQVS GNPQDHIDAL KSIRKQEPKG NPSLQNALEM ARGLLLPVPA HCTREVLIVF 120
  121 GSLSTTDPGD IHQTIDSLVS EKIRVKVLGL SAQVAICKEL CKATNYGDES FYKILLDETH 180
  181 LKELFNEAVT PLPVNKINKG FTLVKMGFPT RIFEDTPTFC SCHSKLVYG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.69897
Match: 1a8x__
Description: No description for 1a8x__ was found.

Predicted Domain #3
Region A:
Residues: [346-461]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYFCPNCHSK VCSLPTVCPC CDLMLILSTH LARSYHHLMP LKTFAEVPTT EKFRSEDCFS  60
   61 CQSRFPILKN HKNGKLLTSS RYRCEDCKQE FCVDCDVFIH EILHNCPGCE SKPVIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 95.325697
Match: 1e53A_
Description: TFIIH p44 subunit cysteine-rich domain

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle