YRC Public Data Repository - Protein Structure Prediction

Protein:	NAP1
Organism:	Saccharomyces cerevisiae
Length:	417 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NAP1.

Description	E-value	Query Range	Subject Range
NAP1_YEAST - Nucleosome assembly protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NAP1 PE=1 SV... gi\|151941588 - gi\|151941588\|gb\|EDN59951.1\| nucleosome assembly protein I [Saccharomyces cerevisiae YJM789] NAP1 - Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamic...	0.0	[1..417]	[1..417]
YGNB_SCHPO - Putative nucleosome assembly protein C2D10.11C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843... SPBC2D10.11c - nucleosome assembly protein Nap2	7.0E-84	[17..396]	[16..371]
gi\|38197428 - gi\|38197428\|gb\|AAH61811.1\| Unknown (protein for MGC:72278) [Rattus norvegicus] NP1L1_MOUSE - Nucleosome assembly protein 1-like 1 OS=Mus musculus GN=Nap1l1 PE=1 SV=2	1.0E-79	[34..361]	[16..343]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-79	[68..361]	[1..294]
NAP1L1 - nucleosome assembly protein 1-like 1 gi\|114645918 - gi\|114645918\|ref\|XP_509226.2\| PREDICTED: nucleosome assembly protein 1-like 1 isoform 14 [Pan troglo... gi\|157928695, gi... - gi\|61359093\|gb\|AAX41667.1\| nucleosome assembly protein 1-like 1 [synthetic construct], gi\|168277932\|...	1.0E-78	[38..361]	[20..343]
FBpp0297132, FBp... - The gene Nucleosome assembly protein 1 is referred to in FlyBase by the symbol Dmel\Nap1 (CG5330, FB... gi\|220960326, gi... - gi\|220960326\|gb\|ACL92699.1\| Nap1-PA [synthetic construct], gi\|220943826\|gb\|ACL84456.1\| Nap1-PA [synt...	1.0E-77	[44..365]	[6..324]

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Predicted Domain #1

Region A:
Residues: [1-81]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDPIRTKPK SSMQIDNAPT PHNTPASVLN PSYLKNGNPV RAQAQEQDDK IGTINEEDIL  60
   61 ANQPLLLQSI QDRLGSLVGQ D

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
histone binding	4.83364158381373	bayes_pls_golite062009
binding	2.67502047678266	bayes_pls_golite062009
DNA binding	1.77868687163103	bayes_pls_golite062009
nucleic acid binding	1.77336286476068	bayes_pls_golite062009
protein binding	1.58681138679309	bayes_pls_golite062009
sequence-specific DNA binding	0.0196905966923535	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [82-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGYVGGLPKN VKEKLLSLKT LQSELFEVEK EFQVEMFELE NKFLQKYKPI WEQRSRIISG  60
   61 QEQPKPEQIA KGQEIVESLN ETELLVDEEE KAQNDSEEEQ VKGIPSFWLT ALENLPIVCD 120
  121 TITDRDAEVL EYLQDIGLEY LTDGRPGFKL LFRFDSSANP FFTNDILCKT YFYQKELGYS 180
  181 GDFIYDHAEG CEISWKDNAH NVTVDLEMRK QRNKTTKQVR TIEKITPIES FFNFFDPPKI 240
  241 QNEDQDEELE EDLEERLALD YSIGEQLKDK LIPRAVDWFT GAALEFEFEE DEEEADEDED 300
  301 EEEDDDHGLE DDDGESAEEQ DDFAGRPEQA PECKQS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	151.30103
Match:	PF00956
Description:	Nucleosome assembly protein (NAP)

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: