YRC Public Data Repository - Protein Structure Prediction

Protein:	YKR023W
Organism:	Saccharomyces cerevisiae
Length:	530 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR023W.

Description	E-value	Query Range	Subject Range
YK03_YEAST - Uncharacterized protein YKR023W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YKR023W ... YKR023W - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi...	0.0	[1..530]	[1..530]
YEX1_SCHPO - Uncharacterized protein C1A6.01c OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC1A6.0... SPAC1A6.01c - human thyroid receptor interacting protein homolog	6.0E-97	[12..378]	[7..349]
gi\|6522544, gi\|1... - gi\|6522544\|emb\|CAB61987.1\| putative protein [Arabidopsis thaliana], gi\|19310635\|gb\|AAL85048.1\| unkno...	2.0E-57	[40..317]	[43..286]
CG11710-PB, FBpp... - This gene is referred to in FlyBase by the symbol Dmel\CG11710 (CG11710, FBgn0031115). It is a prote...	5.0E-55	[130..324]	[76..274]
TRIP4 - thyroid hormone receptor interactor 4	8.0E-55	[130..335]	[9..225]
asc-1 - status:Confirmed UniProt:Q9NAA3 protein_id:CAB70106.2	3.0E-45	[143..312]	[3..178]

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Predicted Domain #1

Region A:
Residues: [1-118]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRKQAIDYA IKQVPQILPL EESDVKALCE QVLSTSSDDP EQIASKFLEF LGHEDLSFEF  60
   61 VMKFNELLNQ NDKKEEKKTK NVHLEHTAPT SWKNESKQPT NNYINKKGDE KPKKLKDE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	1.03363756201359	bayes_pls_golite062009
protein binding	0.12136520713995	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [119-345]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKSSTTRPTV QPSNQSTQSN PIKEKKEHRS KGKLQSLQEI DEAIKMLELR DSGSSKNCNC  60
   61 QGTRHPVFDI APNCLHCGKV VCVIEGLNKG KCGHCHEQLI SDNERTQMVE ILNQEKNELN 120
  121 GSSSSLSNAS NGANVPKKKT KTYKITSGMG KNLFAEQDKL FDFIERKRER ERKRNEVLKL 180
  181 QEEKEESEAK ERQASEHDHK AEENPELLAA QERLDRLLYF QDTSAER

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [346-530]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKIIDNASDF DMNQEVGLWG SARERALALK KQQRNLRKWE KVEKERNGRR EKYVVSMNIG  60
   61 SNGKVTMTEV PKDTENVIAG SDDDISDISD EEDISDLKHI HALKSEINTT KSLENLHLQS 120
  121 KAWDYERDKK QFDRPTYVKK NSDTAQQNRK TEEKAHDMQA YDLKSRVQVD QNADASVEQN 180
  181 ILAVL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: