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View Structure Prediction Details

Protein: COS9
Organism: Saccharomyces cerevisiae
Length: 407 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COS9.

Description E-value Query
Range
Subject
Range
COS4_YEAST - Protein COS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COS4 PE=1 SV=1
COS4 - Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-enc...
577.0 [0..26] [404..1]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQIVRSCNSN NKPLIPSSNW HIAIRMRGDG VKDRSIDVLS LKHFESQKVV LPQDLFMDNF  60
   61 TWMFYEFFKC FTFRTWLLLL LLMWLPGFL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [90-199]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQIKSINRIF PFKLCILVSC LVGIFLPNIY SFSHKSVLTN QLTQFSKEIV EHAPGTDTHD  60
   61 WETVAANLNS YFYENKAWNT EYFFFNAAEC QKAFRKVLLE PFSVKKDESS 

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 49.356547
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.904 N/A N/A a.2.17 Description not found.

Predicted Domain #3
Region A:
Residues: [200-272]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KIKSFGDSVP YIEEALQVYS TEFDKKWKLF NTEKVWSPDN LEHVQLPKKT YRYKFTWVLK  60
   61 RIFNLWLFPA FIL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [273-407]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLACIYVSWD KGHLFRILCC GGGFLLMVRV FQNMRPFSMH MEDKMQFLST IINEQESGAN  60
   61 GWDEIAKKMN RYLFEKKVWT SEEFFFDGID CEWFFNHFFY RLLSTKKPMF DRPLNVELWP 120
  121 YIKEAQLTRK QAPPV

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 59.481486
Match: PF00674
Description: DUP family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle