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View Structure Prediction Details

Protein: EAP1
Organism: Saccharomyces cerevisiae
Length: 632 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EAP1.

Description E-value Query
Range
Subject
Range
EAP1 - eIF4E-associated protein, competes with eIF4G for binding to eIF4E; inhibits cap-dependent translati...
EAP1_YEAST - Protein EAP1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EAP1 PE=1 SV=1
0.0 [1..632] [1..632]
gi|9294015, gi|1... - gi|9294015|dbj|BAB01918.1| unnamed protein product [Arabidopsis thaliana], gi|15231330|ref|NP_187982...
0.0 [203..475] [137..397]
gi|10880466 - gi|10880466|gb|AAG24263.1|AF106957_1 dual-specific kinase DSK1 [Nicotiana tabacum]
1.0E-77 [227..475] [35..278]
gi|185134396, gi... - gi|6681410|dbj|BAA88670.1| galectin like protein [Oncorhynchus mykiss], gi|185134396|ref|NP_00111766...
2.0E-4 [514..591] [133..225]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELNDPSIIS SSQFSGELSD SDTAAATHKS QQAISNLFQK LAKKGREEKP IGSVESSTDS  60
   61 SNISVATSGN NKESNKKKNK KTAMLNFSSL TDPITNYKPM DLQYKTYAYS MNELYHLKPS 120
  121 LASASYEEDP LISELVRSLP KRKFWRLRMG PPDQKHANNH HFNGNNGGGS WKAGYKNG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [179-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNDERRMSRT KNMQGGKRRS QQDDEEKKID QEMLEMDKNL QLGGDVGHSI ADFEDWKAKM  60
   61 KELELKKLSK SKGISNSTAI APRESASHET PTDLRPVIPR GPSSITDFLN LKRQDKKEES 120
  121 SQQTPGIPVG QPSLSKTSIE QVNELETNSD LGKSSSSRFS SFFNKSATSL PSLDNNNQVP 180
  181 SSNVSVVNND GNSTPHQSGS RLMSFFKESR SSTPNAESQL LSASDKDNGK MQTLPQFQQQ 240
  241 PQQMQPMAFT QHPPNNNAFF NGLLNKGKSE TSTPPPPPPG LIAHQGPQFP VMGVPPNFPQ 300
  301 RMMPPPPGLV QFQK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.51
Match: 1ei3A
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [493-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSKDVNKKED RQLRQNKNPN GTRNSKGKQE ETATPDLPQQ QYMPPPPPPG FFPMHPNFPN  60
   61 GPMPPLPQGF PIPPNGMLPV TGQQPQPPYP NMMLQGNFPP NFQQGFGSNS PMPIPSIINA 120
  121 NGKNVTNQLP PGLNSKKNIK 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.32
Match: 1ldvA
Description: No description for 1ldvA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle