YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: TOR2
Organism: Saccharomyces cerevisiae
Length: 2473 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOR2.

Description E-value Query
Range
Subject
Range
TOR2 - PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth i...
TOR2_YEAST - Serine/threonine-protein kinase TOR2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOR...
0.0 [1..2473] [1..2474]
MTOR_RAT - Serine/threonine-protein kinase mTOR OS=Rattus norvegicus GN=Mtor PE=1 SV=1
0.0 [63..2473] [4..2549]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [90..2473] [4..2337]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [1..2473] [1..2474]
MTOR - mechanistic target of rapamycin (serine/threonine kinase)
0.0 [63..2473] [4..2549]
TOR_ARATH - Serine/threonine-protein kinase TOR OS=Arabidopsis thaliana GN=TOR PE=1 SV=1
0.0 [46..2473] [1..2481]

Back

Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKYINKYTT PPNLLSLRQR AEGKHRTRKK LTHKSHSHDD EMSTTSNTDS NHNGPNDSGR  60
   61 VITGSAGHIG KISFV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [76-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSELDTTFST LNLIFDKLKS DVPQERASGA NELSTTLTSL AREVSAEQFQ RFSNSLNNKI  60
   61 FELIHGFTSS EKIGGILAVD TLISFYLSTE ELPNQTSRLA NYLRVLIPSS DIEVMRLAAN 120
  121 TLGRLTVPGG TLTSDFVEFE VRTCIDWLTL TADNNSSSSK LEYRRHAALL IIKALADNSP 180
  181 YLLYPYVNSI LDNIWVPLRD AKLIIRLDAA VALGKCLTII QDRDPALGKQ WFQRLFQGCT 240
  241 HGLSLNTNDS VHATLLVFRE LLSLKAPYLR DKYDDIYKST MKYKEYKFDV IRREVYAILP 300
  301 LLAAFDPAIF TKKYLDRIMV HYLRYLKNID MNAA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 11.19
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [410-563]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNSDKPFILV SIGDIAFEVG SSISPYMTLI LDNIREGLRT KFKVRKQFEK DLFYCIGKLA  60
   61 CALGPAFAKH LNKDLLNLML NCPMSDHMQE TLMILNEKIP SLESTVNSRI LNLLSISLSG 120
  121 EKFIQSNQYD FNNQFSIEKA RKSRNQSFMK KTGE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [564-1014]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNDDITDAQI LIQCFKMLQL IHHQYSLTEF VRLITISYIE HEDSSVRKLA ALTSCDLFIK  60
   61 DDICKQTSVH ALHSVSEVLS KLLMIAITDP VAEIRLEILQ HLGSNFDPQL AQPDNLRLLF 120
  121 MALNDEIFGI QLEAIKIIGR LSSVNPAYVV PSLRKTLLEL LTQLKFSNMP KKKEESATLL 180
  181 CTLINSSDEV AKPYIDPILD VILPKCQDAS SAVASTALKV LGELSVVGGK EMTRYLKELM 240
  241 PLIINTFQDQ SNSFKRDAAL TTLGQLAASS GYVVGPLLDY PELLGILINI LKTENNPHIR 300
  301 RGTVRLIGIL GALDPYKHRE IEVTSNSKSS VEQNAPSIDI ALLMQGVSPS NDEYYPTVVI 360
  361 HNLMKILNDP SLSIHHTAAI QAIMHIFQNL GLRCVSFLDQ IIPGIILVMR SCPPSQLDFY 420
  421 FQQLGSLISI VKQHIRPHVE KIYGVIREFF P

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1015-1094]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIKLQITIIS VIESISKALE GEFKRFVPET LTFFLDILEN DQSNKRIVPI RILKSLVTFG  60
   61 PNLEDYSHLI MPIVVRMTEY 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.768 0.919 G1 phase of mitotic cell cycle a.74.1 Cyclin-like

Predicted Domain #6
Region A:
Residues: [1095-1230]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SAGSLKKISI ITLGRLAKNI NLSEMSSRIV QALVRILNNG DRELTKATMN TLSLLLLQLG  60
   61 TDFVVFVPVI NKALLRNRIQ HSVYDQLVNK LLNNECLPTN IIFDKENEVP ERKNYEDEMQ 120
  121 VTKLPVNQNI LKNAWY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.898 0.040 vacuolar membrane a.118.9 ENTH/VHS domain

Predicted Domain #7
Region A:
Residues: [1231-1309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CSQQKTKEDW QEWIRRLSIQ LLKESPSACL RSCSSLVSVY YPLARELFNA SFSSCWVELQ  60
   61 TSYQEDLIQA LCKALSSSE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.857 0.921 G1 phase of mitotic cell cycle a.74.1 Cyclin-like

Predicted Domain #8
Region A:
Residues: [1310-1601]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPPEIYQMLL NLVEFMEHDD KPLPIPIHTL GKYAQKCHAF AKALHYKEVE FLEEPKNSTI  60
   61 EALISINNQL HQTDSAIGIL KHAQQHNELQ LKETWYEKLQ RWEDALAAYN EKEAAGEDSV 120
  121 EVMMGKLRSL YALGEWEELS KLASEKWGTA KPEVKKAMAP LAAAAWGLEQ WDEIAQYTSV 180
  181 MKSQSPDKEF YDAILCLHRN NFKKAEVHIF NARDLLVTEL SALVNESYNR AYNVVVRAQI 240
  241 IAELEEIIKY KKLPQNSDKR LTMRETWNTR LLGCQKNIDV WQRILRVRSL VI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [1602-1940]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPKEDAQVRI KFANLCRKSG RMALAKKVLN TLLEETDDPD HPNTAKASPP VVYAQLKYLW  60
   61 ATGLQDEALK QLINFTSRMA HDLGLDPNNM IAQSVPQQSK RVPRHVEDYT KLLARCFLKQ 120
  121 GEWRVCLQPK WRLSNPDSIL GSYLLATHFD NTWYKAWHNW ALANFEVISM LTSVSKKKQE 180
  181 GSDASSVTDI NEFDNGMIGV NTFDAKEVHY SSNLIHRHVI PAIKGFFHSI SLSESSSLQD 240
  241 ALRLLTLWFT FGGIPEATQA MHEGFNLIQI GTWLEVLPQL ISRIHQPNQI VSRSLLSLLS 300
  301 DLGKAHPQAL VYPLMVAIKS ESLSRQKAAL SIIEKMRIH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1941-2083]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPVLVDQAEL VSHELIRMAV LWHEQWYEGL DDASRQFFGE HNTEKMFAAL EPLYEMLKRG  60
   61 PETLREISFQ NSFGRDLNDA YEWLMNYKKS KDVSNLNQAW DIYYNVFRKI GKQLPQLQTL 120
  121 ELQHVSPKLL SAHDLELAVP GTR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 347.218487
Match: 1aueA_
Description: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
Matching Structure (courtesy of the PDB):

Predicted Domain #11
Region A:
Residues: [2084-2473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASGGKPIVKI SKFEPVFSVI SSKQRPRKFC IKGSDGKDYK YVLKGHEDIR QDSLVMQLFG  60
   61 LVNTLLQNDA ECFRRHLDIQ QYPAIPLSPK SGLLGWVPNS DTFHVLIREH REAKKIPLNI 120
  121 EHWVMLQMAP DYDNLTLLQK VEVFTYALNN TEGQDLYKVL WLKSRSSETW LERRTTYTRS 180
  181 LAVMSMTGYI LGLGDRHPSN LMLDRITGKV IHIDFGDCFE AAILREKFPE KVPFRLTRML 240
  241 TYAMEVSGIE GSFRITCENV MKVLRDNKGS LMAILEAFAF DPLINWGFDL PTKKIEEETG 300
  301 IQLPVMNANE LLSNGAITEE EVQRVENEHK NAIRNARAML VLKRITDKLT GNDIRRFNDL 360
  361 DVPEQVDKLI QQATSVENLC QHYIGWCPFW 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle