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View Structure Prediction Details

Protein: KKQ8
Organism: Saccharomyces cerevisiae
Length: 734 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KKQ8.

Description E-value Query
Range
Subject
Range
KKQ8_YEAST - Probable serine/threonine-protein kinase KKQ8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
KKQ8 - Putative serine/threonine protein kinase with unknown cellular role
755.0 [0..11] [734..1]
gi|18175903 - gi|18175903|gb|AAL59948.1| putative calcium-dependent protein kinase [Arabidopsis thaliana]
444.0 [0..351] [733..6]
gi|16904226 - gi|16904226|gb|AAL30820.1|AF435452_1 calcium/calmodulin-dependent protein kinase CaMK3 [Nicotiana ta...
441.0 [0..289] [733..28]
gi|7434364, gi|1... - pir||T09940 calcium-dependent protein kinase (EC 2.7.1.-) CDPK - pumpkin, gi|1899175|gb|AAB49984.1| ...
437.0 [0..309] [733..8]
gi|5916094, gi|1... - gi|5916094|gb|AAD55890.1|AF134054_1 checkpoint kinase Chk2 [Rattus norvegicus], gi|16758490|ref|NP_4...
437.0 [0..194] [725..3]

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Predicted Domain #1
Region A:
Residues: [1-223]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMDSKTLTAS MVMQEEKKRQ QPVTRRVRSF SESFKNLFRP PRSRDSSPIN VTRIPYRSSS  60
   61 TSPKRSSEPP RRSTVSAQIL DPKNSPIRQR SYTLKCCTPG LSHPFRQTGS GASNSPTRHR 120
  121 SISGEEQEIV NSLPEYKRSA SHTFHGIRRP RSRSSSVSSC DSSNGTTSSS DSQWAMDSLL 180
  181 DDSDNDLTPY RGSNKDILKS KDRAPYNYID DYNKKALRRA TSY

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 8.91
Match:
Description: No description for 1ldvA was found.

Predicted Domain #2
Region A:
Residues: [224-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNPLPSKQFY NERLYTRRSH PDEESLESLP RFAGADVQCI IEQNGFKVYE DGSHEHNIKL  60
   61 SGVIAKLEKG NSLPAHRQGS LSRPRLGITL SGLFKHHKNE CDIENALSLL PNVEKSQTNH 120
  121 EKRTGQSPND SNRSSPTQGR EDYLKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [370-528]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VNPDASLGSD ELKLINSLSS RIHKSLQNYL QEKNLKPAEC IGEQAPTFQD NYGHPVGLVG  60
   61 AGAYGEVKLC ARLRNEKDSP PFETYHDSKY IYYAVKELKP KPDSDLEKFC TKITSEFIIG 120
  121 HSLSHYHKNG KKPAPNILNV FDILEDSSSF IEVMEFCPA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 260.035458
Match: 1a06A
Description: CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [529-734]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDLYGMLVGK SKLKGRLHPL EADCFMKQLL HGVKFMHDHG IAHCDLKPEN ILFYPHGLLK  60
   61 ICDFGTSSVF QTAWERRVHA QKGIIGSEPY VAPEEFVDGE YYDPRLIDCW SCGVVYITMI 120
  121 LGHYLWKVAS REKDMSYDEF YKEMQRKNQF RVFEELKHVN SELATNRKIA LYRIFQWEPR 180
  181 KRISVGKLLD MQWMKSTNCC LIYDST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 260.035458
Match: 1a06A
Description: CALMODULIN-DEPENDENT PROTEIN KINASE FROM RAT
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle