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View Structure Prediction Details

Protein: YKL133C
Organism: Saccharomyces cerevisiae
Length: 463 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL133C.

Description E-value Query
Range
Subject
Range
YKL133C - Putative protein of unknown function; has similarity to Mgr3p, but unlike MGR3, is not required for ...
0.0 [1..463] [1..463]
SPAP27G11.02 - TPR repeat protein, unknown biological role
YIO2_SCHPO - TPR repeat-containing protein P27G11.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SP...
0.002 [78..209] [60..185]

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Predicted Domain #1
Region A:
Residues: [1-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWKYLHRSVK NEGTVERLTN LNLFTNHRFK FYSTLKEQSF WRIPFKRRSK LQKWVLSTGI  60
   61 VSFIAFNIWW VYWPHHTFPK PVAKILRKGL HSEIKKEGAN YQKSLEYYLE ALEECKAENV 120
  121 DLLSDEYTGI EIKIGEMYEK LHMYNDATAL YGDMLKKFYN ELSKTTDKST KRKFFLLKRD 180
  181 LQILVRFNEI NKDSETNATL LIMHLLLAQR EFLENSPEFK NVLSKSELLN NQQLDWKNFK 240
  241 GLPFIGKSKP DIQMHLNSKR KQELKIKEPE SEQCVFMKEL LTARDLYTRY CLNRSNLSGA 300
  301 LNSKITTLEW MLLADSPLDD ILLAQAELGS IFYLNSEKFE GSLYAIDNEP YKKSEPLELI 360
  361 RSRLQENQNS CLQYSADCYK SIISFANENQ YPKVAMESEM DQRILKALSL AHYGIGVINL 420
  421 HKGRLRASKK ELKKAIRISE MIRFNELIEE AQRELKKVDG TPI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [77-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFPKPVAKIL RKGLHSEIKK EGANYQKSLE YYLEALEECK AENVDLLSDE YTGIEIKIGE  60
   61 MYEKLHMYND ATALYGDMLK KFYNELSKTT DKSTKRKFFL LKRDLQILVR FNEINKDSET 120
  121 NATLLIMHLL LAQREFLENS PEFKNVLSKS ELLNNQQLDW KNFKGLPFIG KSKPDIQMHL 180
  181 NSKRKQELKI KEPESEQCVF MKELLTARDL YTRYCLNRSN LSGALNSKIT TLEWMLLADS 240
  241 PLDDILLAQA ELGSIFYLNS EKFEGSLYAI DNEPYKKSEP LELIRSRLQE NQNSCLQYSA 300
  301 DCYKSIISFA NENQYPKVAM ESEMDQRILK ALSLAHYGIG VINLHKGRLR ASKKELKKAI 360
  361 RISEMIRFNE LIEEAQRELK KVDGTPI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.28
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.368635156671458 bayes_pls_golite062009
protein binding 0.0497625993066355 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle