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View Structure Prediction Details

Protein: SSH4
Organism: Saccharomyces cerevisiae
Length: 579 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SSH4.

Description E-value Query
Range
Subject
Range
SSH4 - Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the ...
SSH4_YEAST - Protein SSH4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SSH4 PE=1 SV=2
0.0 [1..579] [1..579]
gi|3329496, gi|7... - gi|7949051|ref|NP_058085.1| heterogeneous nuclear ribonucleoprotein U [Mus musculus], gi|3329496|gb|...
4.0E-66 [70..414] [150..499]
gi|2108232 - gi|2108232|gb|AAB58117.1| [Prot=RyR1 isform from fish] Fish RyR1 isoform, complete sequence
9.0E-63 [185..452] [628..904]
RYR1_RABIT - Ryanodine receptor 1 OS=Oryctolagus cuniculus GN=RYR1 PE=1 SV=1
3.0E-60 [185..452] [623..899]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
3.0E-60 [185..452] [623..899]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-59 [185..452] [623..899]
RYR1_PIG - Ryanodine receptor 1 OS=Sus scrofa GN=RYR1 PE=2 SV=2
4.0E-59 [185..452] [623..899]

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Predicted Domain #1
Region A:
Residues: [1-184]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYVTFNEALD SSFGNLESPN HDFKVGDPNM VPTPPMDSDS AAISLAFLIS LSITFAILML  60
   61 ILVVIAAYVT FCGDDESEYD EENALGTRTS GTLHSLFGKK HSGILLDSSF ASPGGFDDEI 120
  121 VLQERELEEL PKMSAYEVEL YIRAKEFQMM SPPMVKDFGT YLDSDDQQFI KDRGIQSYFL 180
  181 LPSI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [185-421]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDNIDEYGNF LPSFIVQDKL DIQFSKFNKS SSTVMNYPLP HNRKDAVYFE VKIFRHIQKS  60
   61 NSIFSIGLTT VPYPYFRVPG MAKYSIAYES TGKLRINNPF TASTLLPKLE EGDTVGFGYR 120
  121 YKTGTIFITH NGKKLMDVTQ NIGIDLFIGI GAFNAAYTRT YTRDGLLEDP DNVSFREALS 180
  181 EGKDIEVAKD LQRVHDPHDE SDEMTSDEVE LHVNLGQVGF VFIEANVKKY AFGSVYG

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 21.744727
Match: PF00622
Description: SPRY domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
hydrolase activity 1.4534000838308 bayes_pls_golite062009
binding 1.37879632043452 bayes_pls_golite062009
protein binding 1.15590148654655 bayes_pls_golite062009
sugar binding 1.14331447813206 bayes_pls_golite062009
transporter activity 0.0373253642688324 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [422-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QIGIPPAYNG TEIKKDTILQ KGEELPPRYA DTDNFFGSMK VKEGSSSRIT AQTSKPLWSV  60
   61 GTYERISSNF DRENNVYHDS LETDDNNTDN NVNNNDENAG CNENSPLLED DGNKRPENSN 120
  121 TPREVSDGAI NKNPRNKSTK KRQRNRGKSS KKKNRSRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle