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View Structure Prediction Details

Protein: CUE2
Organism: Saccharomyces cerevisiae
Length: 443 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CUE2.

Description E-value Query
Range
Subject
Range
CUE2 - Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramole...
CUE2_YEAST - Ubiquitin-binding protein CUE2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CUE2 PE=1...
0.0 [1..443] [1..443]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-35 [344..439] [85..167]
SPCC1235.03 - SMR and CUE domain protein
YCY3_SCHPO - Smr domain-containing protein C1235.03 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPC...
3.0E-33 [344..439] [306..388]
gi|7243207 - gi|7243207|dbj|BAA92651.1| KIAA1413 protein [Homo sapiens]
0.001 [347..430] [1320..1388]

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Predicted Domain #1
Region A:
Residues: [1-52]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMDNNDDHE SKLSILMDMF PAISKSKLQV HLLENNNDLD LTIGLLLKEN DD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.236572
Match: PF02845
Description: CUE domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [53-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSTVDNELHQ LYDMFPQLDC SVIKDQFVIN EKSVESTISD LLNYETLQKL K

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.585027
Match: PF02845
Description: CUE domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [104-331]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNQANSPDSV KRNEKKNNWE STNDHIESII KFTDAPKNIA QEYLAENGFD TVKAIIKIIL  60
   61 DYYDKRDFKK DVDTFKVKRS PNTTVRGGRV QSSTGLAHVL KKGKESANVA QESLKRPRSY 120
  121 KHSLDSPQMV ELNELVADNR DLKAINHEFL QKCLQFYDGD VVKVLNISSL LIEDDKNITK 180
  181 TWNFDEGFTL TSRDNCKQHL PKFSTPQISR RNEVGNTYKL PLHDKETP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [332-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGAVPVINNL FQTYRLDFHG FLPSEAVSTL KLALNKWWSK EVAERELNSH NINSYGSKVQ  60
   61 FVSPLIVVTG RGIHSIGGIS KVRLQVKSFL EKNHYIFWEE SSYFRIEGKK KK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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