YRC Public Data Repository - Protein Structure Prediction

Protein:	HOT13
Organism:	Saccharomyces cerevisiae
Length:	116 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOT13.

Description	E-value	Query Range	Subject Range
HOT13_YEAST - Helper of Tim protein 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOT13 PE=1 SV=1 gi\|190409746 - gi\|190409746\|gb\|EDV13011.1\| assembly factor for the Translocase of the Inner Membrane complexes [Sac... HOT13 - Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small ...	5.0E-40	[1..116]	[1..116]
YEMC_SCHPO - Uncharacterized protein C29B12.12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC29B1... SPAC29B12.12 - helper of TIM	6.0E-31	[4..110]	[10..112]
gi\|15923727, gi\|... - gi\|15923727\|ref\|NP_371261.1\| hypothetical protein SAV0737 [Staphylococcus aureus subsp. aureus Mu50]... gi\|15926414, gi\|... - gi\|15926414\|ref\|NP_373947.1\| hypothetical protein SA0692 [Staphylococcus aureus subsp. aureus N315],... gi\|49482994, gi\|... - gi\|49482994\|ref\|YP_040218.1\| hypothetical protein SAR0791 [Staphylococcus aureus subsp. aureus MRSA2... gi\|49244052, gi\|... - gi\|49485609\|ref\|YP_042830.1\| hypothetical protein SAS0702 [Staphylococcus aureus subsp. aureus MSSA4... gi\|156721200, gi... - gi\|156979065\|ref\|YP_001441324.1\| hypothetical protein SAHV_0734 [Staphylococcus aureus subsp. aureus... gi\|25353254 - pir\|\|B89846 conserved hypothetical protein SA0692 [imported] - Staphylococcus aureus (strain N315) gi\|150373718, gi... - gi\|151220918\|ref\|YP_001331740.1\| hypothetical protein NWMN_0706 [Staphylococcus aureus subsp. aureus... gi\|21282428, gi\|... - gi\|21282428\|ref\|NP_645516.1\| hypothetical protein MW0699 [Staphylococcus aureus subsp. aureus MW2], ... gi\|221140824 - gi\|221140824\|ref\|ZP_03565317.1\| hypothetical protein SauraJ_04198 [Staphylococcus aureus subsp. aure... gi\|227246435, gi... - gi\|227557171\|ref\|ZP_03987218.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|227899263, gi... - gi\|227899263\|ref\|ZP_04017068.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|251802813, gi... - gi\|251813707\|ref\|ZP_04828180.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|253315830 - gi\|253315830\|ref\|ZP_04839043.1\| hypothetical protein SauraC_06725 [Staphylococcus aureus subsp. aure... gi\|253731365, gi... - gi\|253731365\|ref\|ZP_04865530.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|253732815, gi... - gi\|253732815\|ref\|ZP_04866980.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|255005528 - gi\|255005528\|ref\|ZP_05144129.2\| hypothetical protein SauraM_03635 [Staphylococcus aureus subsp. aure... gi\|90582497, gi\|... - gi\|90582497\|ref\|ZP_01238260.1\| CHY zinc finger [Staphylococcus aureus subsp. aureus JH1], gi\|9042828... gi\|57285761, gi\|... - gi\|57651575\|ref\|YP_185674.1\| hypothetical protein SACOL0800 [Staphylococcus aureus subsp. aureus COL... gi\|90585254, gi\|... - gi\|90585254\|ref\|ZP_01240964.1\| CHY zinc finger [Staphylococcus aureus subsp. aureus JH9], gi\|9043098... gi\|88194515, gi\|... - gi\|88194515\|ref\|YP_499310.1\| hypothetical protein SAOUHSC_00751 [Staphylococcus aureus subsp. aureus... gi\|82655972, gi\|... - gi\|82750441\|ref\|YP_416182.1\| hypothetical protein SAB0689c [Staphylococcus aureus RF122], gi\|8265597... gi\|221137636 - gi\|221137636\|ref\|ZP_03562442.1\| hypothetical protein SauraJK_03148 [Staphylococcus aureus subsp. aur...	5.0E-29	[6..109]	[4..103]
gi\|25353253 - pir\|\|D95166 conserved hypothetical protein SP1428 [imported] - Streptococcus pneumoniae (strain TIGR... gi\|14972917, gi\|... - gi\|15901281\|ref\|NP_345885.1\| hypothetical protein SP_1428 [Streptococcus pneumoniae TIGR4], gi\|14972... gi\|148990557, gi... - gi\|148990557\|ref\|ZP_01821683.1\| hypothetical protein CGSSp6BS73_01188 [Streptococcus pneumoniae SP6-...	2.0E-27	[8..109]	[6..103]
gi\|21909686, gi\|... - gi\|21909686\|ref\|NP_663954.1\| hypothetical protein SpyM3_0150 [Streptococcus pyogenes MGAS315], gi\|21... gi\|19747458, gi\|... - gi\|19747458\|gb\|AAL96989.1\| hypothetical protein spyM18_0191 [Streptococcus pyogenes MGAS8232], gi\|19... gi\|209539950, gi... - gi\|209558749\|ref\|YP_002285221.1\| hypothetical protein Spy49_0182 [Streptococcus pyogenes NZ131], gi\|... gi\|28895067, gi\|... - gi\|28895067\|ref\|NP_801417.1\| hypothetical protein SPs0155 [Streptococcus pyogenes SSI-1], gi\|2881031... gi\|139473040, gi... - gi\|139473040\|ref\|YP_001127755.1\| CHY zinc finger protein [Streptococcus pyogenes str. Manfredo], gi\|... gi\|71801935, gi\|... - gi\|71902840\|ref\|YP_279643.1\| zinc finger protein [Streptococcus pyogenes MGAS6180], gi\|71801935\|gb\|A... gi\|94989688, gi\|... - gi\|94989688\|ref\|YP_597788.1\| Zinc finger protein [Streptococcus pyogenes MGAS10270], gi\|94543196\|gb\|... gi\|94991684, gi\|... - gi\|94991684\|ref\|YP_599783.1\| Zinc finger protein [Streptococcus pyogenes MGAS2096], gi\|94545192\|gb\|A... gi\|94541317, gi\|... - gi\|94987809\|ref\|YP_595910.1\| zinc finger protein [Streptococcus pyogenes MGAS9429], gi\|94541317\|gb\|A...	1.0E-26	[4..108]	[2..99]
gi\|15674404, gi\|... - gi\|15674404\|ref\|NP_268578.1\| hypothetical protein SPy_0205 [Streptococcus pyogenes M1 GAS], gi\|13621... gi\|71909990, gi\|... - gi\|71909990\|ref\|YP_281540.1\| zinc finger protein [Streptococcus pyogenes MGAS5005], gi\|71852772\|gb\|A...	6.0E-26	[4..108]	[2..99]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-17	[18..96]	[13..86]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIETAIYGKT VDDQSRCVHW HLPKDVIAIR FKCCDKYYAC FECHQELSSH PLEKYDLLDD  60
   61 ANKHLIICGV CRHEMTFAEY YDYNSNLICP NCRSPFNPGC KLHYHLYFQN PPPAMC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	2.27826637472119	bayes_pls_golite062009
protein binding	1.29668949042818	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: