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View Structure Prediction Details

Protein: YKL050C
Organism: Saccharomyces cerevisiae
Length: 922 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKL050C.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
4.0E-96 [3..749] [1144..1937]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
6.0E-96 [3..749] [1145..1938]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
1.0E-95 [3..749] [1146..1939]
gi|8250661 - gi|8250661|gb|AAB29713.2| myosin heavy chain [Rattus sp.]
1.0E-95 [3..749] [99..892]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-95 [3..749] [143..936]
gi|6683485 - gi|6683485|dbj|BAA89233.1| skeletal myosin heavy chain [Gallus gallus]
2.0E-95 [3..749] [1146..1939]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLISALQTT DVESVQTSPE QITERKAVRV STLQESLHSS EMHRAAPETP RSISNSVHKL  60
   61 KTIYSTYQQS GQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [73-395]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLSKEAIFRA KQKYGILNTP ANYKTLGLGD SKSESVDLAA RLASKRTKVS PDDCVETAIE  60
   61 QKARGEAFKV TFSKIPLTPP EDVPITVNLG LKGRRDFLTR LAAQKALAFS PSLDNSMKGT 120
  121 SDSSSVKKKR FSGAPIGNEF DANLVNPQHP AGFKSLDLSK VLDGAERRAI SRVNDRLYPQ 180
  181 KVNFKNGLQS SDQSGVSKAN KEVFKKGTLE KLEHSAEQFL ESHAGNERQR LSDQQYMCAK 240
  241 GAADAVKDLD PKTLEDPDFA AREAQKKLYI KQVASPVVLN EAQKLANRKL QDIDSRDTYM 300
  301 LLFGNQAYNK LAVNIALQHY SVK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.154902
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [396-619]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEEKKKIYLG GGLWMTPEEV NAVAKKLISP VVNEIDERAS RQRDVDKDIE RRSRVLDQEY  60
   61 EDGNSMERAK EQNDGQLLLA MASKQQQEKE AKKAEEGQRY DQFVQKMNIK LQQKEKELEN 120
  121 ARENRENLRN ELQERLSKNL SGENDELNDW NDACERDLKN SSIEHYYAVR SHFDNLGNSE 180
  181 RGYDELLEER SKIQVEIERL VASIAEHKTA IHGFGETADA GGAI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.045757
Match: 1c1gA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [620-868]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PAVQKQKIPT RKDLLDATVN DPLVISAEMA KEEAEMATEE CMLKELQVDE MIIIRNIMLR  60
   61 ECEKKLEEEK ETAKRSRRGT EESKNNSNFS RDVIMSTPDN NEKVTPIGKS ASPKDVVKSR 120
  121 FLSTYNTGKD IDSSASARSI TGVSGVLDDG PKTPTSNKEN ELIDDEVKSY KVHQAVDGTG 180
  181 EDSIANKRDK SSRPAANSGG SITIEQFLFN KNADKQGLSK TESVTMKREP VVDQMDSKKG 240
  241 HDFTHCNDN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [869-922]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRRSFSGFSQ GSIENDYSNE VTDDQDDQEG SEIRVRDSND SNTSPKESFF KEVI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle