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View Structure Prediction Details

Protein: AAD10
Organism: Saccharomyces cerevisiae
Length: 288 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AAD10.

Description E-value Query
Range
Subject
Range
ALKR4_ARATH - Probable aldo-keto reductase 4 OS=Arabidopsis thaliana GN=At1g60710 PE=2 SV=1
3.0E-74 [2..282] [75..341]
AAD14 - Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; ...
AAD14_YEAST - Putative aryl-alcohol dehydrogenase AAD14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
1.0E-73 [1..288] [89..376]
gi|17938565, gi|... - gi|17938565|ref|NP_535354.1| oxidoreductase [Agrobacterium tumefaciens str. C58], gi|17743396|gb|AAL...
gi|25316287, gi|... - pir||AH3156 oxidoreductase mocA [imported] - Agrobacterium tumefaciens (strain C58, Dupont), pir||...
1.0E-68 [7..263] [82..330]
gi|15075864 - gi|15075864|emb|CAC47418.1| Putative oxidoreductase [Sinorhizobium meliloti 1021]
gi|15966592 - gi|15966592|ref|NP_386945.1| putative oxidoreductase protein [Sinorhizobium meliloti 1021]
1.0E-68 [2..263] [74..329]

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Predicted Domain #1
Region A:
Residues: [1-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRKLRDQI VIATKFTTDY KGYDVGKGKS ANFCGNHKRS LHVSVRDSLR KLQTDWIDIL  60
   61 YVHWWDYMSS IEEVMDSLHI LVQQGKVLYL GVSDTPAWVV SAANYYATSH GKTPFSIYQG 120
  121 KWNVLNRDFE RDIIPMARHF GMALAPWDVM GGGRFQSKKA VEERKKKGEG LRTFFGTSEQ 180
  181 TDMEVKISEA LLKVAEEHGT ESVTAIAIAY VRSKAKHVFP LVGGRKIEHL KQNIEALSIK 240
  241 LTPEQIKYLE SIVPFDVGFP TNFIGDDPAV TKKPSFLTEM SAKISFED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 186.218487
Match: 1gveB_
Description: Aflatoxin aldehyde reductase (akr7a1)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
aldo-keto reductase activity 2.78826040220575 bayes_pls_golite062009
aldehyde reductase activity 1.71780727668617 bayes_pls_golite062009
catalytic activity 1.68179794468736 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.76912620964527 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.731893663103321 bayes_pls_golite062009
binding 0.40308700211307 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle