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View Structure Prediction Details

Protein: PGU1
Organism: Saccharomyces cerevisiae
Length: 361 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGU1.

Description E-value Query
Range		 Subject
Range
PGLR_COCCA - Polygalacturonase OS=Cochliobolus carbonum GN=PGN1 PE=3 SV=1
 3.0E-93 [1..361] [10..364]
PGLRA_ASPPA - Probable endopolygalacturonase A OS=Aspergillus parasiticus GN=pgaA PE=2 SV=1
 4.0E-93 [2..361] [6..363]
PGLR_ACTCH - Polygalacturonase precursor - Actinidia chinensis (Kiwi) (Yangtao)
PGLR_ACTDE - Polygalacturonase OS=Actinidia deliciosa PE=2 SV=1
gi|166325|gb|AAC... - polygalacturonase [Actinidia deliciosa]
 2.0E-92 [11..353] [86..443]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 5.0E-92 [11..361] [55..410]
gi|25289363, gi|... - gi|91806353|gb|ABE65904.1| polygalacturonase/pectinase [Arabidopsis thaliana], pir||E84871 probable ...
 1.0E-91 [1..356] [7..374]
gi|3747093 - gi|3747093|gb|AAC64184.1| endopolygalacturonase [Prunus persica]
 5.0E-91 [3..361] [16..392]
PGLRB_ASPNG - Endopolygalacturonase B OS=Aspergillus niger GN=pgaB PE=1 SV=1
PGLRB_ASPNC - Probable endopolygalacturonase B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=pgaB PE=3 ...
 1.0E-90 [1..361] [1..360]
gi|6289088 - gi|6289088|gb|AAF06810.1|AF195791_1 polygalacturonase [Penicillium griseoroseum]
 2.0E-90 [1..361] [9..376]

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Predicted Domain #1
Region A:
Residues: [1-361] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISANSLLIS TLCAFAIATP LSKRDSCTLT GSSLSSLSTV KKCSSIVIKD LTVPAGQTLD  60
   61 LTGLSSGTTV TFEGTTTFQY KEWSGPLISI SGSKISVVGA SGHTIDGQGA KWWDGLGDSG 120
  121 KVKPKFVKLA LTGTSKVTGL NIKNAPHQVF SINKCSDLTI SDITIDIRDG DSAGGHNTDG 180
  181 FDVGSSSNVL IQGCTVYNQD DCIAVNSGST IKFMNNYCYN GHGISVGSVG GRSDNTVNGF 240
  241 WAENNHVINS DNGLRIKTVE GATGTVTNVN FISNKISGIK SYGIVIEGDY LNSKTTGTAT 300
  301 GGVPISNLVM KDITGSVNST AKRVKILVKN ATNWQWSGVS ITGGSSYSGC SGIPSGSGAS 360
  361 C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 886.144602
Match: 1czfA_
Description: Polygalacturonase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
polygalacturonase activity 4.87547461518877 bayes_pls_golite062009
hydrolase activity 0.715715894047629 bayes_pls_golite062009
catalytic activity 0.67288476528593 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 0.1751072403659 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle