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View Structure Prediction Details

Protein: STE24
Organism: Saccharomyces cerevisiae
Length: 453 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STE24.

Description E-value Query
Range
Subject
Range
STE24 - Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal...
STE24_YEAST - CAAX prenyl protease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE24 PE=1 SV=1
0.0 [1..453] [1..453]
gi|12718381 - gi|12718381|emb|CAC28689.1| probable zinc metallo-protease [Neurospora crassa]
0.0 [4..444] [7..430]
FACE1_ARATH - CAAX prenyl protease 1 homolog OS=Arabidopsis thaliana GN=FACE1 PE=1 SV=1
0.0 [13..451] [3..423]
SPAC3H1.05 - CAAX prenyl protease
STE24_SCHPO - Probable CAAX prenyl protease 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC3H1.05...
2.0E-93 [4..453] [37..474]
gi|3721864 - gi|3721864|dbj|BAA33727.1| Ste24p [Homo sapiens]
4.0E-88 [19..447] [23..472]
fce-1 - Zinc-binding metalloprotease domain status:Confirmed UniProt:Q9XVE5 protein_id:CAB03839.1
3.0E-83 [19..452] [10..442]
gi|13897556 - gi|13897556|gb|AAK48429.1|AF252544_1 putative CAAX prenyl protease 1 [Trypanosoma cruzi]
1.0E-82 [29..450] [23..426]

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Predicted Domain #1
Region A:
Residues: [1-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDLKTILDH PNIPWKLIIS GFSIAQFSFE SYLTYRQYQK LSETKLPPVL EDEIDDETFH  60
   61 KSRNYSRAKA KFSIFGDVYN LAQKLVFIKY DLFPKIWHMA VSLLNAVLPV RFHMVSTVAQ 120
  121 SLCFLGLLSS LSTLVDLPLS YYSHFVLEEK FGFNKLTVQL WITDMIKSLT LAYAIGGPIL 180
  181 YLFLKIFDKF PTDFLWYIMV FLFVVQILAM TIIPVFIMPM FNKFTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [227-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEDGELKKSI ESLADRVGFP LDKIFVIDGS KRSSHSNAYF TGLPFTSKRI VLFDTLVNSN  60
   61 STDEITAVLA HEIGHWQKNH IVNMVIFSQL HTFLIFSLFT SIYRNTSFYN TFGFFLEKST 120
  121 GSFVDPVITK EFPIIIGFML FNDLLTPLEC AMQFVMSLIS RTHEYQADAY AKKLGYKQNL 180
  181 CRALIDLQIK NLSTMNVDPL YSSYHYSHPT LAERLTALDY VSEKKKN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 67.200659
Match: PF01435
Description: Peptidase family M48

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle