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View Structure Prediction Details

Protein: STE24
Organism: Saccharomyces cerevisiae
Length: 453 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STE24.

Description E-value Query
Range
Subject
Range
STE24 - Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal...
STE24_YEAST - CAAX prenyl protease 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=STE24 PE=1 SV=1
0.0 [1..453] [1..453]
gi|12718381 - gi|12718381|emb|CAC28689.1| probable zinc metallo-protease [Neurospora crassa]
0.0 [4..444] [7..430]
FACE1_ARATH - CAAX prenyl protease 1 homolog OS=Arabidopsis thaliana GN=FACE1 PE=1 SV=1
0.0 [13..451] [3..423]
SPAC3H1.05 - CAAX prenyl protease
STE24_SCHPO - Probable CAAX prenyl protease 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC3H1.05...
2.0E-93 [4..453] [37..474]
gi|3721864 - gi|3721864|dbj|BAA33727.1| Ste24p [Homo sapiens]
4.0E-88 [19..447] [23..472]
fce-1 - Zinc-binding metalloprotease domain status:Confirmed UniProt:Q9XVE5 protein_id:CAB03839.1
3.0E-83 [19..452] [10..442]
gi|13897556 - gi|13897556|gb|AAK48429.1|AF252544_1 putative CAAX prenyl protease 1 [Trypanosoma cruzi]
1.0E-82 [29..450] [23..426]

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Predicted Domain #1
Region A:
Residues: [1-226]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDLKTILDH PNIPWKLIIS GFSIAQFSFE SYLTYRQYQK LSETKLPPVL EDEIDDETFH  60
   61 KSRNYSRAKA KFSIFGDVYN LAQKLVFIKY DLFPKIWHMA VSLLNAVLPV RFHMVSTVAQ 120
  121 SLCFLGLLSS LSTLVDLPLS YYSHFVLEEK FGFNKLTVQL WITDMIKSLT LAYAIGGPIL 180
  181 YLFLKIFDKF PTDFLWYIMV FLFVVQILAM TIIPVFIMPM FNKFTP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [227-453]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEDGELKKSI ESLADRVGFP LDKIFVIDGS KRSSHSNAYF TGLPFTSKRI VLFDTLVNSN  60
   61 STDEITAVLA HEIGHWQKNH IVNMVIFSQL HTFLIFSLFT SIYRNTSFYN TFGFFLEKST 120
  121 GSFVDPVITK EFPIIIGFML FNDLLTPLEC AMQFVMSLIS RTHEYQADAY AKKLGYKQNL 180
  181 CRALIDLQIK NLSTMNVDPL YSSYHYSHPT LAERLTALDY VSEKKKN

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 67.200659
Match: PF01435
Description: Peptidase family M48

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle