YRC Public Data Repository - Protein Structure Prediction

Protein:	JJJ3
Organism:	Saccharomyces cerevisiae
Length:	172 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JJJ3.

Description	E-value	Query Range	Subject Range
DNAJ_GEOSE - Chaperone protein DnaJ OS=Geobacillus stearothermophilus GN=dnaJ PE=3 SV=1	1.0E-42	[4..155]	[1..151]
DNAJ_SALCH - Chaperone protein DnaJ OS=Salmonella choleraesuis GN=dnaJ PE=3 SV=3 DNAJ_SALTY - Chaperone protein DnaJ OS=Salmonella typhimurium GN=dnaJ PE=2 SV=2 DNAJ_SALPB - Chaperone protein dnaJ OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=dnaJ PE=3 SV=1 gi\|168234750, gi... - gi\|197292013\|gb\|EDY31363.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Schw... gi\|205335216, gi... - gi\|205335216\|gb\|EDZ21980.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Kent... gi\|205331430, gi... - gi\|205331430\|gb\|EDZ18194.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar 4,[5... gi\|167552158, gi... - gi\|205323117\|gb\|EDZ10956.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Sain... lcl\|NC_016856.1_... - [gene=dnaJ] [protein=chaperone protein DnaJ] [protein_id=YP_005235647.1] [location=13595..14734] DNAJ_SALTI - Chaperone protein DnaJ OS=Salmonella typhi GN=dnaJ PE=3 SV=2 DNAJ_SALTY - Chaperone protein DnaJ OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=dnaJ PE=3 ... DNAJ_SALTI - Chaperone protein dnaJ OS=Salmonella typhi GN=dnaJ PE=2 SV=2 DNAJ_SALTY - Chaperone protein dnaJ OS=Salmonella typhimurium GN=dnaJ PE=2 SV=2 gi\|200386746, gi... - gi\|200386746\|ref\|ZP_03213358.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALDC - Chaperone protein DnaJ OS=Salmonella dublin (strain CT_02021853) GN=dnaJ PE=3 SV=1 gi\|238910770 - gi\|238910770\|ref\|ZP_04654607.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|197261782, gi... - gi\|197261782\|ref\|ZP_03161856.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALA4 - Chaperone protein DnaJ OS=Salmonella agona (strain SL483) GN=dnaJ PE=3 SV=1 gi\|213052055 - gi\|213052055\|ref\|ZP_03344933.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALEP - Chaperone protein DnaJ OS=Salmonella enteritidis PT4 (strain P125109) GN=dnaJ PE=3 SV=1 DNAJ_SALG2 - Chaperone protein DnaJ OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=dnaJ PE=3 SV=1 gi\|204927085, gi... - gi\|204927085\|ref\|ZP_03218287.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|168822157, gi... - gi\|205341422\|gb\|EDZ28186.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Welt... gi\|168464463, gi... - gi\|195633028\|gb\|EDX51482.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Newp... gi\|205348796, gi... - gi\|205348796\|gb\|EDZ35427.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Hada... gi\|168244484, gi... - gi\|205336608\|gb\|EDZ23372.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Heid... DNAJ_SALSV - Chaperone protein DnaJ OS=Salmonella schwarzengrund (strain CVM19633) GN=dnaJ PE=3 SV=1 gi\|194455583, gi... - gi\|194469219\|ref\|ZP_03075203.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALHS - Chaperone protein DnaJ OS=Salmonella heidelberg (strain SL476) GN=dnaJ PE=3 SV=1 DNAJ_SALNS - Chaperone protein DnaJ OS=Salmonella newport (strain SL254) GN=dnaJ PE=3 SV=1 gi\|213864898 - gi\|213864898\|ref\|ZP_03387017.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|213647263 - gi\|213647263\|ref\|ZP_03377316.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|213616376 - gi\|213616376\|ref\|ZP_03372202.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|213426531 - gi\|213426531\|ref\|ZP_03359281.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... DNAJ_SALPC - Chaperone protein DnaJ OS=Salmonella paratyphi C (strain RKS4594) GN=dnaJ PE=3 SV=1 gi\|214001206 - gi\|214001206\|ref\|ZP_03411941.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar ... gi\|29136180, gi\|... - gi\|29140556\|ref\|NP_803898.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Typ... gi\|16759006 - gi\|16759006\|ref\|NP_454623.1\| chaperone protein DnaJ [Salmonella enterica subsp. enterica serovar Typ... DNAJ_SALPB - Chaperone protein DnaJ OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=dnaJ PE=3 SV=1 DNAJ_SALCH - Chaperone protein DnaJ OS=Salmonella choleraesuis (strain SC-B67) GN=dnaJ PE=3 SV=3 DNAJ_SALCH - Chaperone protein dnaJ OS=Salmonella choleraesuis GN=dnaJ PE=3 SV=3	8.0E-42	[4..155]	[1..150]
DNAJ_THEVO - Chaperone protein dnaJ OS=Thermoplasma volcanium GN=dnaJ PE=3 SV=1 DNAJ_THEVO - Chaperone protein DnaJ OS=Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 154...	4.0E-41	[7..156]	[3..156]
gi\|19262995, gi\|... - gi\|74096171\|ref\|NP_001027731.1\| heat shock protein 40 [Ciona intestinalis], gi\|19262995\|dbj\|BAB85846...	8.0E-41	[8..168]	[4..165]
gi\|311086467\|gb\|... - chaperone protein DnaJ [Buchnera aphidicola str. TLW03 (Acyrthosiphon pisum)] DNAJ_BUCA5 - Chaperone protein DnaJ OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A) GN=dnaJ PE=3 SV... gi\|311085894\|gb\|... - chaperone protein DnaJ [Buchnera aphidicola str. LL01 (Acyrthosiphon pisum)] DNAJ_BUCAI - Chaperone protein dnaJ OS=Buchnera aphidicola subsp. Acyrthosiphon pisum GN=dnaJ PE=3 SV=2 gi\|25296014 - gi\|25296014\|pir\|\|F84947 dnaJ protein [imported] - Buchnera sp. (strain APS) DNAJ_BUCAI - Chaperone protein DnaJ OS=Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) GN=dnaJ PE=3 S... gi\|257471208\|ref... - DnaJ protein [Buchnera aphidicola str. LSR1 (Acyrthosiphon pisum)]	2.0E-40	[4..155]	[1..148]
DNAJ_GEOTM - Chaperone protein DnaJ OS=Geobacillus thermoglucosidasius GN=dnaJ PE=3 SV=1	2.0E-40	[4..155]	[1..151]
gi\|188495716, gi... - gi\|75515606\|ref\|ZP_00737763.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|168785065, gi... - gi\|189374927\|gb\|EDU93343.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC869], gi\|1687850... sp\|B7UI60\|DNAJ_ECO27 - Chaperone protein dnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_SHISS - Chaperone protein DnaJ OS=Shigella sonnei (strain Ss046) GN=dnaJ PE=3 SV=1 gi\|168762775, gi... - gi\|189366928\|gb\|EDU85344.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC4501], gi\|168762... gi\|192956076, gi... - gi\|75234578\|ref\|ZP_00718919.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECOSM - Chaperone protein DnaJ OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=dnaJ PE=3 SV=1 gi\|193065637, gi... - gi\|75256327\|ref\|ZP_00727999.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|189379547, gi... - gi\|189379547\|gb\|EDU97963.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. EC508], gi\|1687979... DNAJ_ECO27 - Chaperone protein DnaJ OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOSE - Chaperone protein DnaJ OS=Escherichia coli (strain SE11) GN=dnaJ PE=3 SV=1 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6 GN=dnaJ PE=2 SV=3 DNAJ_ESCF3 - Chaperone protein DnaJ OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) GN=dn... gi\|217325343, gi... - gi\|217325343\|ref\|ZP_03441427.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. TW14588], gi\|2... DNAJ_ECOUT - Chaperone protein DnaJ OS=Escherichia coli (strain UTI89 / UPEC) GN=dnaJ PE=3 SV=1 gi\|15829269, gi\|... - gi\|15829269\|ref\|NP_308042.1\| chaperone protein DnaJ [Escherichia coli O157:H7 str. Sakai], gi\|133594... gi\|75229476, gi\|... - gi\|75229476\|ref\|ZP_00716026.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... gi\|75235742, gi\|... - gi\|75235742\|ref\|ZP_00719906.1\| COG0484: DnaJ-class molecular chaperone with C-terminal Zn finger dom... DNAJ_ECO24 - Chaperone protein DnaJ OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=dnaJ PE=3 SV=1 DNAJ_ECOHS - Chaperone protein DnaJ OS=Escherichia coli O9:H4 (strain HS) GN=dnaJ PE=3 SV=1 gi\|209747186, gi... - pir\|\|G85481 chaperone with DnaK, heat shock protein [imported] - Escherichia coli (strain O157:H7, s... DNAJ_ECO57 - Chaperone protein DnaJ OS=Escherichia coli O157:H7 GN=dnaJ PE=3 SV=3 DNAJ_ECOL6 - Chaperone protein DnaJ OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=dnaJ PE=3 S... DNAJ_ECO45 - Chaperone protein DnaJ OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|12512693, gi\|... - gi\|15799695\|ref\|NP_285707.1\| chaperone protein DnaJ [Escherichia coli O157:H7 EDL933], gi\|12512693\|g... DNAJ_ECO8A - Chaperone protein DnaJ OS=Escherichia coli O8 (strain IAI1) GN=dnaJ PE=3 SV=1 DNAJ_ECO55 - Chaperone protein DnaJ OS=Escherichia coli (strain 55989 / EAEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO81 - Chaperone protein DnaJ OS=Escherichia coli O81 (strain ED1a) GN=dnaJ PE=3 SV=1 DNAJ_ECOLU - Chaperone protein DnaJ OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=dnaJ PE=3 SV=1 DNAJ_ECO7I - Chaperone protein DnaJ OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=dnaJ PE=3 SV=1 gi\|227837919, gi... - gi\|227885090\|ref\|ZP_04002895.1\| chaperone protein DnaJ [Escherichia coli 83972], gi\|227837919\|gb\|EEJ... gi\|229560216 - gi\|229560216\|ref\|YP_667956.2\| chaperone protein DnaJ [Escherichia coli 536] gi\|229775981 - gi\|229775981\|ref\|YP_851221.2\| chaperone protein DnaJ [Escherichia coli APEC O1] DNAJ_ECOLC - Chaperone protein DnaJ OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=dnaJ PE=3 SV=1	3.0E-40	[4..155]	[1..147]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-40	[4..155]	[1..148]
gi\|89106899, gi\|... - gi\|89106899\|ref\|AP_000679.1\| chaperone Hsp40, co-chaperone with DnaK [Escherichia coli str. K-12 sub... DNAJ_ECODH - Chaperone protein DnaJ OS=Escherichia coli (strain K12 / DH10B) GN=dnaJ PE=3 SV=1 DNAJ_ECOLI - Chaperone protein dnaJ (Heat shock protein J) (HSP40) - Escherichia coli EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN... EG10240 - chaperone Hsp40, DnaK co-chaperone / DnaK co-chaperone HSP40; DNA-binding protein; stress-related DN...	5.0E-40	[4..155]	[1..147]
DNAJ_THEAC - Chaperone protein DnaJ OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 1... DNAJ_THEAC - Chaperone protein dnaJ OS=Thermoplasma acidophilum GN=dnaJ PE=3 SV=1	5.0E-40	[7..155]	[3..155]

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Predicted Domain #1

Region A:
Residues: [1-172]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLVNSLTHY EILRIPSDAT QDEIKKAYRN RLLNTHPDKL SKSIHDTVSN VTINKIQDAY  60
   61 KILSNIKTRR EYDRLILENY KRQGFHNCGD GLDEFSLDDF SFDEDKLEFM MNCPRCQFVG 120
  121 GFHFSESLLD ECIDNVDAME RSHSGYQLLT QCSACSLWLK VNFDIEEEQE GQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.616428
Match:	1xbl__
Description:	DnaJ chaperone, N-terminal (J) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.03854863870179	bayes_pls_golite062009
protein binding	1.59319415069732	bayes_pls_golite062009
transcription regulator activity	1.2131700498174	bayes_pls_golite062009
nucleic acid binding	1.12971478797926	bayes_pls_golite062009
DNA binding	0.8788643398536	bayes_pls_golite062009
unfolded protein binding	0.26936882742456	bayes_pls_golite062009
catalytic activity	0.106988907594358	bayes_pls_golite062009
protein kinase activity	0.0820836328401214	bayes_pls_golite062009
heat shock protein binding	0.0438718605428136	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [115-172]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RCQFVGGFHF SESLLDECID NVDAMERSHS GYQLLTQCSA CSLWLKVNFD IEEEQEGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.37
Match:	1wgeA
Description:	Solution structure of the mouse DESR1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.49983036545301	bayes_pls_golite062009
protein binding	0.535832402793455	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: