YRC Public Data Repository - Protein Structure Prediction

Protein:	PEX2
Organism:	Saccharomyces cerevisiae
Length:	271 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX2.

Description	E-value	Query Range	Subject Range
gi\|151944926 - gi\|151944926\|gb\|EDN63181.1\| peroxin [Saccharomyces cerevisiae YJM789] PEX2_YEAST - Peroxisomal biogenesis factor 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PEX2 PE=... PEX2 - RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms ...	3.0E-94	[1..271]	[1..271]
gi\|227548 - gi\|227548\|prf\|\|1706355A peroxisome assembly factor 1 gi\|57645 - gi\|57645\|emb\|CAA41054.1\| peroxisome assembly factor-1 [Rattus rattus] PEX2_RAT - Peroxisome biogenesis factor 2 OS=Rattus norvegicus GN=Pex2 PE=2 SV=1	1.0E-78	[3..261]	[16..285]
gi\|254028172, gi... - gi\|74214570\|dbj\|BAE31130.1\| unnamed protein product [Mus musculus], gi\|74185307\|dbj\|BAE30130.1\| unna...	5.0E-77	[3..261]	[16..285]
PEX2 - peroxisomal biogenesis factor 2 gi\|208968651 - gi\|208968651\|dbj\|BAG74164.1\| peroxisomal membrane protein 3, 35kDa [synthetic construct]	1.0E-75	[3..261]	[16..285]
PEX2_CRIGR - Peroxisome biogenesis factor 2 OS=Cricetulus griseus GN=PEX2 PE=1 SV=1	4.0E-74	[3..260]	[15..283]
PEX2_ARATH - Peroxisome biogenesis protein 2 OS=Arabidopsis thaliana GN=PEX2 PE=1 SV=1	8.0E-59	[1..259]	[37..317]
gi\|15384797 - gi\|15384797\|emb\|CAC59701.1\| peroxin-2 [Trypanosoma brucei]	9.0E-57	[3..261]	[40..322]
gi\|220944468, gi... - gi\|220954342\|gb\|ACL89714.1\| CG7081-PA [synthetic construct], gi\|220944468\|gb\|ACL84777.1\| CG7081-PA [... CG7081-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7081 (CG7081, FBgn0035876). It is a protein...	3.0E-56	[3..262]	[9..272]

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Predicted Domain #1

Region A:
Residues: [1-165]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRVAQLDSI ALDKELYGQF WSEFNAAFNT SEHKEEWELA LNTVVFMCAT RFLPHYGSSC  60
   61 TYGSALSGVV FQCRKRTLYV VTVLAGYVWK KITHIIFNGP HCGNQMMWLK LYKWVNLLYH 120
  121 GCDVTNFLRF LAAEGPNARA FLSPLYRAFN VHSTRLIRDG SAIAS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [166-271]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EFYSNSVFAG LEYQNRQLLW NALLELFSNT LLTKRGLLTF VKKPPRSRST TTYKTVCPRC  60
   61 GGFPTNPYQI ACCRANYCYV CVVKALEWSM CDACGSSGRL TASPVY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	2.522879
Match:	1chc__
Description:	Immediate early protein, IEEHV
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits