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View Structure Prediction Details

Protein: SWI3
Organism: Saccharomyces cerevisiae
Length: 825 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SWI3.

Description E-value Query
Range
Subject
Range
SWI3 - Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chr...
SWI3_YEAST - SWI/SNF complex subunit SWI3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SWI3 PE=1 S...
0.0 [1..825] [1..825]
ssr2 - SWI /SNF and RSC complex subunit Ssr2
SSR2_SCHPO - SWI/SNF and RSC complexes subunit ssr2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ssr...
0.0 [299..739] [12..455]
SWI3C_ARATH - SWI/SNF complex subunit SWI3C OS=Arabidopsis thaliana GN=SWI3C PE=1 SV=1
4.0E-95 [149..726] [2..652]
gi|6678027, gi|1... - pir||T30967 transcription activator SRG3 - mouse, gi|6678027|ref|NP_033237.1| SWI/SNF related, matr...
4.0E-92 [83..714] [245..809]
gi|32880191, gi|... - gi|32880191|gb|AAP88926.1| SWI/SNF related, matrix associated, actin dependent regulator of chromati...
gi|60654775 - gi|60654775|gb|AAX31952.1| SWI/SNF related matrix associated actin-dependent regulator of chromatin ...
4.0E-90 [83..668] [220..762]
psa-1 - SWI\/SNF protein status:Confirmed UniProt:Q9U2W6 protein_id:CAB54337.2
4.0E-88 [228..742] [3..535]
gi|4220848 - gi|4220848|gb|AAD12718.1| moira [Drosophila melanogaster]
4.0E-77 [89..660] [214..757]

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Predicted Domain #1
Region A:
Residues: [1-6]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENTLG

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [229-308]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSSVANTPSE IPDAHKAEQE DIIEKTESVD KKVDSGEERN EQEREIMNDH SKSANPKKTT  60
   61 ITRVEPETFE IPQAHEIVIP 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #2
Region A:
Residues: [7-79]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EGSTVNASVD VDQHGNDNNS DSNANAAVAG VANTDTAGEE SQQQDESLKD EATVPNTRDA  60
   61 ESEAITVTAK QQP

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #3
Region A:
Residues: [80-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TMQANKLDSQ ETPSTEESRA QNVFGQDNED SDNLFGETES SVSNNEANTP SIPTNPVDNE  60
   61 NNKPAIKEDS TIQDSNGDV

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #4
Region A:
Residues: [159-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNMEDVKIQK EEEPENNTVI EGVKEESQPD ENTKEMDEVE EDDEDDDQPM ISPDNSIFGD  60
   61 TKSESKQLGN 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.29
Match: 1l8mA
Description: No description for 1l8mA was found.

Predicted Domain #5
Region A:
Residues: [309-409]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYSKWFNLEK IHSIEVQSLP EFFTNRIPSK TPEVYMRYRN FMVNSYRLNP NEYFSVTTAR  60
   61 RNVSGDAAAL FRLHKFLTKW GLINYQVDSK LLPKNIEPPL T

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [410-485]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQYSTRHDAP RGLFPFESYK PSVQLPDMAK LKKMMNTSDS ESTLYKYLKE SKRKYDEITH  60
   61 PPSTTDDENG DKNDNG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.154902
Match: 1h8qA_
Description: No description for 1h8qA_ was found.

Predicted Domain #7
Region A:
Residues: [486-596]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKMNNEVSTS TSMTGDANLL EEGETSRPLK KVKILEQIDE NWSKEDLQKL LKGIQEFGAD  60
   61 WYKVAKNVGN KSPEQCILRF LQLPIEDKFL YGDGNGKGDN DNGLGPLKYA P

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.36
Match: 1h88C
Description: c-Myb, DNA-binding domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [597-825]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HLPFSKSENP VLSTIAFLVG LVNPKTVQSM TQRAIQSAES IKSQKEEISD QKPIEHIKEG  60
   61 SEIAISSLGY RSHIFATNEE RQMNFLTNEL IRLQMEKLDA KLNHLKKLEK FMELERKTLE 120
  121 RQQENLLIQR LNFNQNSSKI VNVLSKCLNL ISDSNINNSS VAEKEEIRSQ IDHFKSMLSK 180
  181 PETLSIGKNP FNKPNIETGE NHNGQSISNE NDVKPISIEA PQFYRYWSA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle