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View Structure Prediction Details

Protein: SFH5
Organism: Saccharomyces cerevisiae
Length: 294 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SFH5.

Description E-value Query
Range
Subject
Range
SFH3_ARATH - Phosphatidylinositol/phosphatidylcholine transfer protein SFH3 OS=Arabidopsis thaliana GN=SFH3 PE=2 ...
1.0E-70 [2..278] [41..323]
gi|14486705 - gi|14486705|gb|AAK63247.1|AF367433_1 phosphatidylinositol transfer-like protein III [Lotus japonicus...
4.0E-68 [2..284] [53..344]

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Predicted Domain #1
Region A:
Residues: [1-21]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFDNDSEKQ VFDKLKKAIP G

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [84-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWRREFNPLS CAYKEVHNTE LQNVGILTFD ANGDANKKAV TWNLYGQLVK KKELFQNVDK  60
   61 FVRYRIGLME KGLSLLDFTS SDNNYMTQVH DYKGVSVWRM DSDIKNCSKT VIGIFQKYYP 120
  121 ELLYAKYFVN VPTVFGWVYD LIKKFVDETT RKKFVVLTDG SKLGQYLKDC PYEGYGGKDK 180
  181 KNNLTKQNVT NVHPTEYGLY ILQKQIIEDV E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.0103
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipid transporter activity 4.82372291869245 bayes_pls_golite062009
lipid transporter activity 3.44932625048477 bayes_pls_golite062009
phosphatidylinositol transporter activity 3.08477039249457 bayes_pls_golite062009
binding 1.62756726885066 bayes_pls_golite062009
transporter activity 1.00447017621654 bayes_pls_golite062009
substrate-specific transporter activity 0.658164745879483 bayes_pls_golite062009
retinoid binding 0.19160677048347 bayes_pls_golite062009
isoprenoid binding 0.0787898777092364 bayes_pls_golite062009
protein binding 0.0661922828933662 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [22-83]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIKEKCAGYD ELYGYKLNPE GLTQEEVDKY YDEKIADRLT YKLCKAYQFE YSTIVQNLID  60
   61 IL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.0103
Match: 1aua__
Description: N-terminal domain of phosphatidylinositol transfer protein sec14p; C-terminal domain of phosphatidylinositol transfer protein sec14p
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle