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View Structure Prediction Details

Protein: GLG2
Organism: Saccharomyces cerevisiae
Length: 380 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLG2.

Description E-value Query
Range
Subject
Range
GLG2_YEAST - Glycogenin-2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GLG2 PE=1 SV=1
GLG2 - Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; si...
gi|190409368 - gi|190409368|gb|EDV12633.1| glycogen synthesis initiator [Saccharomyces cerevisiae RM11-1a]
3.0E-98 [1..380] [1..380]
GOLS2_ARATH - Galactinol synthase 2 OS=Arabidopsis thaliana GN=GOLS2 PE=1 SV=1
5.0E-55 [4..316] [21..332]
GYG2 - glycogenin 2
2.0E-51 [6..262] [38..258]
gi|18874402 - gi|18874402|gb|AAL78687.1| galactinol synthase [Cucumis melo]
2.0E-51 [2..316] [16..328]
gi|4588376 - gi|4588376|gb|AAD26116.1|AF106954_1 galactinol synthase [Brassica napus]
8.0E-51 [5..317] [27..330]

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Predicted Domain #1
Region A:
Residues: [1-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKVAICTL LYSRDYLPGA LTLAYQLQKL LKHAVVEDEI TLCLLIEKKL FGDEFKPQEI  60
   61 ALIRSLFKEI IIIEPLKDQE KSIEKNKANL ELLKRPELSH TLLKARLWEL VQFDQVLFLD 120
  121 ADTLPLNKEF FEILRLYPEQ TRFQIAAVPD IGWPDMFNTG VLLLIPDLDM ATSLQDFLIK 180
  181 TVSIDGADQG IFNQFFNPIC NYSKEVLHKV SPLMEWIRLP FTYNVTMPNY GYQSSPAMNF 240
  241 FQQHIRLIHF IGTFKPWSRN TTDYDDHYYQ LWRSTQRELY SECHLSNYFT HLQLGNIE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 279.218487
Match: 1ll0A_
Description: Glycogenin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring hexosyl groups 2.55498472336996 bayes_pls_golite062009
UDP-glycosyltransferase activity 2.14294822366154 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
transferase activity 1.47184463413038 bayes_pls_golite062009
cytidylyltransferase activity 1.14240569193314 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 1.09519444695756 bayes_pls_golite062009
nucleotidyltransferase activity 1.03393419806381 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.897978517422275 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 0.857216989692536 bayes_pls_golite062009
mannosyltransferase activity 0.64885729959093 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.521566400238457 bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity 0.513376694534047 bayes_pls_golite062009
glycogenin glucosyltransferase activity 0.355343910175944 bayes_pls_golite062009
uridylyltransferase activity 0.321928989676507 bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity 0.2363835251362 bayes_pls_golite062009
guanylyltransferase activity 0.0539392112504681 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [299-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TETNFYHEPP CLQDLLNHGK RENQKHVDLD ITSVDRNASQ KSTAEKHDIE KPTSKPQSAF  60
   61 KFDWESTDYL DRVQRAFPKP DT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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