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View Structure Prediction Details

Protein: IML2
Organism: Saccharomyces cerevisiae
Length: 731 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IML2.

Description E-value Query
Range
Subject
Range
IML2 - Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitoch...
gi|190409418 - gi|190409418|gb|EDV12683.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
gi|207344020 - gi|207344020|gb|EDZ71296.1| YJL082Wp-like protein [Saccharomyces cerevisiae AWRI1631]
IML2_YEAST - Mitochondrial outer membrane protein IML2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
0.0 [1..731] [1..731]
TT39B_MACFA - Tetratricopeptide repeat protein 39B OS=Macaca fascicularis GN=TTC39B PE=2 SV=1
0.0 [71..728] [40..628]
gi|2865252 - gi|2865252|gb|AAC39582.1| unknown [Homo sapiens]
0.0 [112..730] [36..561]
SPAC11E3.14 - conserved protein
YDYE_SCHPO - Uncharacterized protein C11E3.14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC11E3....
0.0 [120..728] [54..586]
CE01846 - status:Partially_confirmed UniProt:Q09266 protein_id:AAC46794.1
0.0 [111..726] [54..571]
gi|21312214, gi|... - gi|21312214|ref|NP_082617.1| tetratricopeptide repeat domain 39C [Mus musculus], gi|12850529|dbj|BAB...
0.0 [130..727] [60..575]

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Predicted Domain #1
Region A:
Residues: [1-215]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRVFGSFGS KGNQSSGEEQ STKTKQVLKQ ANDFEIALKA MDFVLDDRTD EGLNLLKKAE  60
   61 METGSDQTIL TLARGVIEFL QATLSFETEE MKRAAITLGK AEQMSWKSKQ NAEKTNFRSS 120
  121 SIYPPGTVYA VTYTESCLLH ALLMLFSESM MEAAKALLKL RRAYTMLQDI MVTVKKAERS 180
  181 KNSSSPSPSE KSQESCGSFV SAETTFISVD IPYKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [216-386]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSEDKSNPLL LEFAEKIYTM RMGRLSGAHI GNTPSFHRLR DDLGLQTTPS QASDRHSVSD  60
   61 DFDLEQATID EFIHSGANLC YGILQVVLSL LPPAIGAVLS IVGFKGSREE GLRLVWKATK 120
  121 ERNVHGCIGL LGLMFYYDGP FQFTDADFDI PPNDNGSRAL NKSRTNDSSL L

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [387-543]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGYMDSATLL HPGKILEDAL LKARALFPNS ALWLLNEAKM LAGKGRLRDS LALMDSIDVN  60
   61 SIRMRQVKSL MVFERAILLV NLHEYNRAAD DLISLLDISD WSHALYTYFA GCCYLENWRM 120
  121 TQLGLLNDGK EQFYKERARE LIFDAPSLLG KKTFKSK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.29
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [544-635]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLPLDRFMLR KVQQFNNMQK KLNLQEPLDS IATSPVHELA YFYNGYNRMT ENDLILTKKM  60
   61 LTEYHNPAID SEDPDQELIR NLLLSLTLRR LG

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.29
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [636-731]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAERGLALLD DIVLPKIFYI QNGKVKYFKK TEDPWAYPAA LYERALFCWK LGGMESLNEC  60
   61 REWLLRAQNY AADYELSTRI GMKIKAALDR VENALA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.29
Match: 1fchA
Description: Peroxin pex5 (peroxisomal targeting signal 1 (PTS1) receptor)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle