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View Structure Prediction Details

Protein: DLS1
Organism: Saccharomyces cerevisiae
Length: 167 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DLS1.

Description E-value Query
Range
Subject
Range
NFYC4_ARATH - Nuclear transcription factor Y subunit C-4 OS=Arabidopsis thaliana GN=NFYC4 PE=2 SV=1
8.0E-44 [13..149] [72..200]
NFYC - nuclear transcription factor Y, gamma
5.0E-41 [19..143] [42..154]
NFYC_MOUSE - Nuclear transcription factor Y subunit gamma OS=Mus musculus GN=Nfyc PE=1 SV=2
2.0E-40 [19..143] [42..154]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-40 [19..143] [42..154]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNETSGKET ASAPLCSPKL PVEKVQRIAK NDPEYMDTSD DAFVATAFAT EFFVQVLTHE  60
   61 SLHRQQQQQQ QQVPPLPDEL TLSYDDISAA IVHSSDGHLQ FLNDVIPTTK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1jfiA_
Description: Negative cofactor 2, NC2, alpha chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA binding 4.49118409263799 bayes_pls_golite062009
nucleic acid binding 4.35201412176948 bayes_pls_golite062009
transcription regulator activity 4.08606081850613 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 4.04353148658823 bayes_pls_golite062009
binding 3.27510691458843 bayes_pls_golite062009
transcription factor activity 2.51581622888695 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.38228606466152 bayes_pls_golite062009
transcription repressor activity 2.3574713307436 bayes_pls_golite062009
transcription corepressor activity 1.30859203490073 bayes_pls_golite062009
transcription activator activity 1.25487495162413 bayes_pls_golite062009
transcription factor binding 1.15204005455906 bayes_pls_golite062009
transcription coactivator activity 1.1297723528047 bayes_pls_golite062009
protein binding 1.07873333188144 bayes_pls_golite062009
transcription cofactor activity 1.01502031330902 bayes_pls_golite062009
sequence-specific DNA binding 0.0852726470007639 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [111-167]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLRLLVEENR VRYTTSVMPP NEVYSAYVVN DTAPKPNIVE IDLDNDEDDD EDVTDQE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.709 d.9.1 Interleukin 8-like chemokines
View Download 0.822 d.9.2 Description not found.
View Download 0.779 d.9.2 Description not found.
View Download 0.738 d.9.2 Description not found.
View Download 0.729 d.9.2 Description not found.
View Download 0.707 d.18.1 ssDNA-binding transcriptional regulator domain
View Download 0.698 d.9.2 Description not found.
View Download 0.693 b.34.1 C-terminal domain of transcriptional repressors
View Download 0.676 d.9.2 Description not found.
View Download 0.674 b.38.1 Sm-like ribonucleoproteins
View Download 0.653 d.9.2 Description not found.
View Download 0.646 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.635 g.18.1 Complement control module/SCR domain
View Download 0.628 d.9.2 Description not found.
View Download 0.627 d.9.2 Description not found.
View Download 0.596 d.50.1 dsRNA-binding domain-like
View Download 0.560 d.9.2 Description not found.
View Download 0.557 b.49.1 N-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.545 d.9.2 Description not found.
View Download 0.535 d.9.1 Interleukin 8-like chemokines
View Download 0.518 b.1.2 Fibronectin type III
View Download 0.500 b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.499 d.9.2 Description not found.
View Download 0.484 b.24.1 Hyaluronate lyase-like, C-terminal domain
View Download 0.460 b.38.1 Sm-like ribonucleoproteins
View Download 0.460 d.9.1 Interleukin 8-like chemokines
View Download 0.449 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.433 d.9.1 Interleukin 8-like chemokines
View Download 0.376 d.9.2 Description not found.
View Download 0.366 b.38.1 Sm-like ribonucleoproteins
View Download 0.346 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.343 b.11.1 gamma-Crystallin-like
View Download 0.342 b.1.2 Fibronectin type III
View Download 0.340 b.1.2 Fibronectin type III
View Download 0.338 b.84.1 Single hybrid motif
View Download 0.331 d.9.1 Interleukin 8-like chemokines
View Download 0.328 b.38.1 Sm-like ribonucleoproteins
View Download 0.325 d.17.1 Cystatin/monellin
View Download 0.325 b.71.1 Glycosyl hydrolase domain
View Download 0.319 b.40.4 Nucleic acid-binding proteins
View Download 0.306 d.17.1 Cystatin/monellin
View Download 0.305 b.71.1 Glycosyl hydrolase domain
View Download 0.304 b.40.4 Nucleic acid-binding proteins
View Download 0.270 d.17.1 Cystatin/monellin
View Download 0.269 b.40.4 Nucleic acid-binding proteins
View Download 0.262 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.259 b.1.2 Fibronectin type III
View Download 0.247 d.17.1 Cystatin/monellin
View Download 0.246 b.1.18 E set domains
View Download 0.242 d.17.1 Cystatin/monellin
View Download 0.239 b.71.1 Glycosyl hydrolase domain
View Download 0.239 b.1.18 E set domains
View Download 0.239 b.40.4 Nucleic acid-binding proteins
View Download 0.239 b.71.1 Glycosyl hydrolase domain
View Download 0.238 b.1.2 Fibronectin type III
View Download 0.237 b.71.1 Glycosyl hydrolase domain
View Download 0.228 b.48.1 mu transposase, C-terminal domain
View Download 0.226 b.1.2 Fibronectin type III
View Download 0.226 d.15.1 Ubiquitin-like
View Download 0.225 b.1.18 E set domains
View Download 0.224 c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.221 d.129.1 TATA-box binding protein-like
View Download 0.220 b.1.2 Fibronectin type III
View Download 0.220 b.1.13 Superoxide reductase-like
View Download 0.217 b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.217 b.38.1 Sm-like ribonucleoproteins
View Download 0.212 d.54.1 Enolase N-terminal domain-like
View Download 0.209 d.129.1 TATA-box binding protein-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle