YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM54
Organism:	Saccharomyces cerevisiae
Length:	478 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM54.

Description	E-value	Query Range	Subject Range
TIM54_CANGA - Mitochondrial import inner membrane translocase subunit TIM54 OS=Candida glabrata GN=TIM54 PE=3 SV=1 TIM54_CANGA - Mitochondrial import inner membrane translocase subunit TIM54 OS=Candida glabrata (strain ATCC 2001 ...	428.0	[0..20]	[469..2]
orf19.12608 - orf19.5143 CGDID:CAL0002576 Assembly 19, Contig19-20219 (42229, 41027) CDS, reverse complemented, tr... gi\|68478058, gi\|... - gi\|68478058\|ref\|XP_716898.1\| hypothetical protein CaO19.12608 [Candida albicans SC5314], gi\|46438585...	373.0	[0..8]	[467..2]
gi\|50419813, gi\|... - gi\|50419813\|ref\|XP_458438.1\| hypothetical protein DEHA0C18502g [Debaryomyces hansenii CBS767], gi\|49... TIM54_DEBHA - Mitochondrial import inner membrane translocase subunit TIM54 - Debaryomyces hansenii (Yeast) (Torul...	355.0	[0..4]	[467..16]
TIM54_ASHGO - Mitochondrial import inner membrane translocase subunit TIM54 OS=Ashbya gossypii (strain ATCC 10895 ... TIM54_ASHGO - Mitochondrial import inner membrane translocase subunit TIM54 OS=Ashbya gossypii GN=TIM54 PE=3 SV=1	330.0	[0..14]	[467..19]
TIM54_KLULA - Mitochondrial import inner membrane translocase subunit TIM54 OS=Kluyveromyces lactis (strain ATCC 8... TIM54_KLULA - Mitochondrial import inner membrane translocase subunit TIM54 OS=Kluyveromyces lactis GN=TIM54 PE=3 ...	282.0	[0..32]	[467..4]
TIM54_SCHPO - Mitochondrial import inner membrane translocase subunit tim54 OS=Schizosaccharomyces pombe (strain 9... tim54 - TIM22 inner membrane protein import complex subunit Tim54	266.0	[0..217]	[456..115]
TIM54_NEUCR - Mitochondrial import inner membrane translocase subunit tim-54 - Neurospora crassa gi\|85068267 - gi\|85068267\|ref\|XP_962149.1\| hypothetical protein NCU07295.1 [Neurospora crassa OR74A]	256.0	[0..26]	[473..2]
gi\|116195674, gi... - gi\|88180348\|gb\|EAQ87816.1\| hypothetical protein CHGG_04435 [Chaetomium globosum CBS 148.51], gi\|1161...	250.0	[0..20]	[473..24]
gi\|49092722, gi\|... - gi\|67526455\|ref\|XP_661289.1\| hypothetical protein AN3685.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	236.0	[0..16]	[476..417]

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Predicted Domain #1

Region A:
Residues: [1-166]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSESGKPIA KPIRKPGYTN PALKALGIPA LRLPSRNWMI FWSVLTVSIG GIAYDKYKQR  60
   61 QILSHATDLV KPLAEESMEV DKVPRKITVF IAPPPNDYLE SSLKVWRRYV KPVLYYAGLD 120
  121 YELVQEDRQG IIRTNVANRI RELRKEILAS TDGQPVKEPN QTVAKP

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [167-339]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGSSTSKISS LLPFNKIIQD PAEEDDSFDP EIGKKFKENF DWRNVIGIFY TMPKPKHIIS  60
   61 EDALTKDPIL SGGVICLGRG AYKEYIAGIH EGLLGPIEKT EKTGSTEPKM TGVVEANQIE 120
  121 SKVSESGATE LVDAEKETAL EEAKVQDDLK VDEENSSEDS QKFLKPFISS DQY

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [340-478]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDLQIASELQ TPNGEFIRNP NTNIPLLINQ PLLVIPIPNL IGFTTIPRRI HRFYQKRFYV  60
   61 EDVCSSVVNC VRQTRIRPFD IAKDIDLAKD EEKDWPQNWV KQGKEKNSEW TQELVCDPRI 120
  121 TKHMFVYEKP PKEEPESDI

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits