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View Structure Prediction Details

Protein: IRC8
Organism: Saccharomyces cerevisiae
Length: 822 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IRC8.

Description E-value Query
Range
Subject
Range
IRC8 - Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent tran...
IRC8_YEAST - Uncharacterized protein IRC8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IRC8 PE=1 S...
0.0 [1..822] [1..822]
gi|1160355 - gi|1160355|gb|AAB00542.1| UNC-89
0.0 [220..673] [1406..1860]
VCAN - versican
gi|225000050 - gi|225000050|gb|AAI72276.1| Versican [synthetic construct]
6.0E-87 [437..786] [2052..2473]
gi|3253302 - gi|3253302|gb|AAC24359.1| versican V1 splice-variant precursor [Bos taurus]
2.0E-80 [424..788] [1043..1484]
gi|46396076 - gi|46396076|sp||P82953_1 [Segment 1 of 7] Mannose-specific lectin (Agglutinin)
1.0E-78 [415..788] [1038..1479]
PGCV_MOUSE, CSPG... - (Q62059) Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteo...
2.0E-74 [163..788] [1767..2451]
AKAP9_RABIT - A-kinase anchor protein 9 (Fragment) OS=Oryctolagus cuniculus GN=AKAP9 PE=2 SV=2
1.0E-70 [233..725] [439..952]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCHNSVRSGN KAGFLGIKFG SALLSIATGA IAIALLCKFH DHEAVLIVIV CSTLLYGIPS  60
   61 LISFITETVF APSKFHIGYF YNVLNFALPL ITMGCTVDYF HNTLRSPISV QSESHRVYIT 120
  121 TLDSLLIFTL FINGIQLGFF LKDGNANNFG SSSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
catalytic activity 0.916346296983561 bayes_pls_golite062009
binding 0.67385346756555 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [155-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NISTDQYDKE ANAVENGRFV PLKNSSQTLT PDLELLHGSP KSMNGVAWLI NELSTNSNTN  60
   61 ANKTISSDEN SNSSVIRHKL GPISTSKCPK KPSHSHFSKL KKYNSFFLGP KENRYKRNTQ 120
  121 QATKVPTEKK SNHRSSQYVS RLSTISDISK SFLNFLALNE KNGNSTSTAR TPSEGRVSII 180
  181 INEGNNTLKY KTPHDSHTID SPNLELEREA IGRINSALLP ACLRVTDKMI SPQQSTQNED 240
  241 SYQATPLIPQ VEVDDDFYVG DILMTNELQD IPQVPRISSD IEDDFEQQYT KHVDLPARVT 300
  301 LEMWEKDQEK ILQKVTTNRD KSKLLPPFRF TSESDMDPST STELEVELHA QNNFSFPFKS 360
  361 AGLQIATSDQ FNQQEFKTSD TISELDEYLH DPSIQEEDAS QLIESSLNQN NLSSTTIDNG 420
  421 PKDMSRFSTR HSPTKSIISM ISGSGSVKHQ HSHSTLSNFF TGHSRNNSQI NQLLQGSSSN 480
  481 MMSNTSPHSS PTKSLRMRFG KKLSLSNISD TMSPYEGSTT DPINYSFGHG HNKNQSI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [692-822]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFSYVRTLQS SHSPTKSTSG NSRRDSLNND RTQSTVNERA LRTASTLFYL QHNNATCTLN  60
   61 GEEPVLDTPQ SIQSSSSGSE QESAGSGSGY PEVVFSEYDR EKWNVLRNLK EIAPEKTIES 120
  121 GPVEELVSPS K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [480-548]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPFRFTSESD MDPSTSTELE VELHAQNNFS FPFKSAGLQI ATSDQFNQQE FKTSDTISEL  60
   61 DEYLHDPSI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [549-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEEDASQLIE SSLNQNNLSS TTIDNGPKDM SRFSTRHSPT KSIISMISGS GSVKHQHSHS  60
   61 TLSNFFTGHS RNNSQINQLL QGSSSNMMSN TSPHSSPTKS LRMRFGKKLS LSNISDTMSP 120
  121 YEGSTTDPIN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [679-822]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YSFGHGHNKN QSIDFSYVRT LQSSHSPTKS TSGNSRRDSL NNDRTQSTVN ERALRTASTL  60
   61 FYLQHNNATC TLNGEEPVLD TPQSIQSSSS GSEQESAGSG SGYPEVVFSE YDREKWNVLR 120
  121 NLKEIAPEKT IESGPVEELV SPSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle