YRC Public Data Repository - Protein Structure Prediction

Protein:	DAL3
Organism:	Saccharomyces cerevisiae
Length:	195 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DAL3.

Description	E-value	Query Range	Subject Range
DAL3 - Ureidoglycolate hydrolase, converts ureidoglycolate to glyoxylate and urea in the third step of alla... ALLA_YEAST - Ureidoglycolate lyase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DAL3 PE=1 SV=1	8.0E-77	[1..195]	[1..195]
ALLA_BRUME - Ureidoglycolate hydrolase OS=Brucella melitensis GN=allA PE=3 SV=1 ALLA_BRUME - Ureidoglycolate lyase OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=all... ALLA_BRUMB - Ureidoglycolate lyase OS=Brucella melitensis biotype 2 (strain ATCC 23457) GN=allA PE=3 SV=1	8.0E-58	[1..188]	[3..158]
ALLA_PSEAB - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=allA PE=3 SV=1 ALLA_PSEA8 - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain LESB58) GN=allA PE=3 SV=1 ALLA_PSEAE - Ureidoglycolate lyase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228... gi\|254239863, gi... - gi\|84328428\|ref\|ZP_00976435.1\| COG3194: Ureidoglycolate hydrolase [Pseudomonas aeruginosa 2192], gi\|... gi\|126166541, gi... - gi\|84321700\|ref\|ZP_00970054.1\| COG3194: Ureidoglycolate hydrolase [Pseudomonas aeruginosa C3719], gi... ALLA_PSEAE - Ureidoglycolate hydrolase OS=Pseudomonas aeruginosa GN=allA PE=3 SV=1	1.0E-56	[1..190]	[1..159]
gi\|25353288, gi\|... - gi\|25353292\|pir\|\|B97639 hypothetical protein AGR_C_4225 [imported] - Agrobacterium tumefaciens (stra... ALLA_AGRFC - Ureidoglycolate lyase OS=Agrobacterium fabrum (strain C58 / ATCC 33970) GN=allA PE=3 SV=1	2.0E-55	[4..191]	[5..160]
ALLA1_RHIME, ALL... - Ureidoglycolate hydrolase 1 OS=Rhizobium meliloti GN=allA1 PE=3 SV=1, (Q92UG4) Ureidoglycolate hydro... ALLA1_RHIME - Ureidoglycolate lyase 1 OS=Rhizobium meliloti (strain 1021) GN=allA1 PE=3 SV=1	3.0E-55	[4..191]	[5..160]
ALLA_RHILO - Ureidoglycolate hydrolase OS=Rhizobium loti GN=allA PE=3 SV=1 ALLA_RHILO - Ureidoglycolate lyase OS=Rhizobium loti (strain MAFF303099) GN=allA PE=3 SV=1	1.0E-54	[1..190]	[1..158]
gi\|25353293, gi\|... - pir\|\|F90699 ureidoglycolate hydrolase [imported] - Escherichia coli (strain O157:H7, substrain RIMD... ALLA_SHIFL - Ureidoglycolate lyase OS=Shigella flexneri GN=allA PE=1 SV=1 gi\|242376284, gi... - gi\|251784011\|ref\|YP_002998315.1\| hypothetical protein B21_00460 [Escherichia coli BL21], gi\|24237628... gi\|30040241, gi\|... - gi\|30061997\|ref\|NP_836168.1\| ureidoglycolate hydrolase [Shigella flexneri 2a str. 2457T], gi\|3004024... gi\|253774506, gi... - gi\|254287377\|ref\|YP_003053125.1\| ureidoglycolate hydrolase [Escherichia coli BL21(DE3)], gi\|25397668... ALLA_ECO57 - Ureidoglycolate lyase OS=Escherichia coli O157:H7 GN=allA PE=1 SV=1 gi\|24111881, gi\|... - gi\|24111881\|ref\|NP_706391.1\| ureidoglycolate hydrolase [Shigella flexneri 2a str. 301], gi\|24050681\|... gi\|253972474, gi... - gi\|254160573\|ref\|YP_003043681.1\| ureidoglycolate hydrolase [Escherichia coli B str. REL606], gi\|2539... gi\|254591095, gi... - gi\|254791695\|ref\|YP_003076532.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. TW14359], ... gi\|12513397, gi\|... - gi\|15800241\|ref\|NP_286253.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 EDL933], gi\|1251339... gi\|194423706, gi... - gi\|83587044\|ref\|ZP_00925674.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli 101-1], gi\|19443... ALLA_SHIB3 - Ureidoglycolate lyase OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=allA PE=3 SV=1 ALLA_ECOHS - Ureidoglycolate lyase OS=Escherichia coli O9:H4 (strain HS) GN=allA PE=3 SV=1 gi\|75229338 - gi\|75229338\|ref\|ZP_00715893.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli B7A] gi\|192959153, gi... - gi\|75239003\|ref\|ZP_00722985.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli E110019], gi\|193... gi\|188017664, gi... - gi\|188017664\|gb\|EDU55786.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4113], gi\|168... gi\|188493003, gi... - gi\|75514624\|ref\|ZP_00736879.1\| COG3194: Ureidoglycolate hydrolase [Escherichia coli 53638], gi\|18849... ALLA_SHIDS - Ureidoglycolate lyase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=allA PE=3 SV=1 gi\|168760330, gi... - gi\|189369157\|gb\|EDU87573.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4501], gi\|168... ALLA_SHIBS - Ureidoglycolate lyase OS=Shigella boydii serotype 4 (strain Sb227) GN=allA PE=3 SV=1 gi\|168754619, gi... - gi\|189358070\|gb\|EDU76489.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|15829820, gi\|... - gi\|15829820\|ref\|NP_308593.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. Sakai], gi\|133... ALLA_SHIF8 - Ureidoglycolate lyase OS=Shigella flexneri serotype 5b (strain 8401) GN=allA PE=3 SV=1 gi\|194419002, gi... - gi\|83570167\|ref\|ZP_00921613.1\| COG3194: Ureidoglycolate hydrolase [Shigella dysenteriae 1012], gi\|19... ALLA_ECO5E - Ureidoglycolate lyase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=allA PE=3 SV=1 gi\|208822890, gi... - gi\|208822890\|ref\|ZP_03263208.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4042], gi... gi\|217324272, gi... - gi\|217324272\|ref\|ZP_03440356.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. TW14588], g... ALLA_ECOSE - Ureidoglycolate lyase OS=Escherichia coli (strain SE11) GN=allA PE=3 SV=1 gi\|187769695, gi... - gi\|187769695\|gb\|EDU33539.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|189362461, gi... - gi\|189362461\|gb\|EDU80880.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|189373573, gi... - gi\|189373573\|gb\|EDU91989.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC869], gi\|1687... gi\|189003093, gi... - gi\|189003093\|gb\|EDU72079.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4076], gi\|168... ALLA_ECOLC - Ureidoglycolate lyase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=allA PE=3 SV=1 gi\|195936075 - gi\|195936075\|ref\|ZP_03081457.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4024] gi\|189379285, gi... - gi\|189379285\|gb\|EDU97701.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC508], gi\|1687... gi\|208732389, gi... - gi\|208815741\|ref\|ZP_03256920.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4045], gi... gi\|208727950, gi... - gi\|208808149\|ref\|ZP_03250486.1\| ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4206], gi... gi\|124529315, gi... - gi\|124529315\|ref\|ZP_01700349.1\| Ureidoglycolate hydrolase [Escherichia coli B], gi\|124499915\|gb\|EAY4...	5.0E-54	[3..192]	[2..158]
ALLA_ECODH - Ureidoglycolate lyase OS=Escherichia coli (strain K12 / DH10B) GN=allA PE=1 SV=1 EG13615 - ureidoglycolate lyase, releasing urea / Ureidoglycolate lyase, releasing urea gi\|85674643, gi\|... - gi\|89107373\|ref\|AP_001153.1\| ureidoglycolate hydrolase [Escherichia coli str. K-12 substr. W3110], g... ALLA_ECOBW - Ureidoglycolate lyase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=allA PE=3 SV=1 EG13615 - ureidoglycolate lyase, releasing urea / Ureidoglycolate lyase, releasing urea ALLA_ECOLI - Ureidoglycolate hydrolase (EC 3.5.3.19) - Escherichia coli	2.0E-53	[3..192]	[2..158]
ALLA_SALTY - Ureidoglycolate hydrolase OS=Salmonella typhimurium GN=allA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=allA] [protein=ureidoglycolate hydrolase] [protein_id=YP_005236218.1] [location=576697..577179... gi\|167990508, gi... - gi\|205330925\|gb\|EDZ17689.1\| ureidoglycolate hydrolase [Salmonella enterica subsp. enterica serovar 4... ALLA_SALTY - Ureidoglycolate hydrolase OS=Salmonella typhimurium GN=allA PE=3 SV=1 ALLA_SALTY - Ureidoglycolate lyase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=allA PE=3 S...	3.0E-52	[3..192]	[2..158]
ALLA_SALEN - Ureidoglycolate hydrolase OS=Salmonella enteritidis GN=allA PE=3 SV=1 ALLA_SALEP - Ureidoglycolate lyase OS=Salmonella enteritidis PT4 (strain P125109) GN=allA PE=3 SV=1 ALLA_SALEN - Ureidoglycolate lyase OS=Salmonella enteritidis GN=allA PE=3 SV=1	8.0E-52	[3..192]	[2..158]

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Predicted Domain #1

Region A:
Residues: [1-195]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTVVAETLT KESFEEYGTI ISPDEEISRM QNLEKGANQG TAIKLLQVSQ VENKSTSKVP  60
   61 NWNLFRCFPQ PHLNRVFTQG SNQAISHSIK VLEKHPCSTQ TFVPMGRTSA EVAYLVVVAK 120
  121 EIGNKPDLST LRAFTCLGNQ AVTYGLGTWH APMIVLGKEE HLDFSVLIYE SLDPDRPEKD 180
  181 CVEEHYSDGD VCIII

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
ureidoglycolate hydrolase activity	2.63080015873229	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1.64225826538892	bayes_pls_golite062009
dioxygenase activity	0.930778069601015	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.901194069960417	bayes_pls_golite062009
binding	0.797072992275176	bayes_pls_golite062009
nucleic acid binding	0.623892372229422	bayes_pls_golite062009
DNA binding	0.483453407263708	bayes_pls_golite062009
transcription regulator activity	0.465649136635506	bayes_pls_golite062009
catalytic activity	0.401988496917198	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: