YRC Public Data Repository - Protein Structure Prediction

Protein:	YVH1
Organism:	Saccharomyces cerevisiae
Length:	364 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YVH1.

Description	E-value	Query Range	Subject Range
PVH1_YEAST - Tyrosine-protein phosphatase YVH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YVH1 P... YVH1 - Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen acc...	0.0	[1..364]	[1..364]
DUS12_MOUSE - Dual specificity protein phosphatase 12 OS=Mus musculus GN=Dusp12 PE=2 SV=1	5.0E-82	[3..346]	[18..328]
DUS12_RAT - Dual specificity protein phosphatase 12 OS=Rattus norvegicus GN=Dusp12 PE=2 SV=1	5.0E-80	[2..345]	[15..327]
DUSP12 - dual specificity phosphatase 12 gi\|60656185, gi\|... - gi\|60656185\|gb\|AAX32656.1\| dual specificity phosphatase 12 [synthetic construct], gi\|123998709\|gb\|AB... ENSPTRT00000002905 - null	2.0E-79	[2..346]	[17..329]
PVH1_SCHPO - Tyrosine-protein phosphatase yvh1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=yvh1 PE=... SPBC17A3.06 - phosphoprotein phosphatase	2.0E-62	[5..342]	[37..324]
MKP-4-PB, FBpp03... - The gene MAPK Phosphatase 4 is referred to in FlyBase by the symbol Dmel\MKP-4 (CG14211, FBgn0031044...	9.0E-59	[9..342]	[33..375]
PTEN1_ARATH - Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and protein-tyrosine-phosphatase PTEN1 OS=Ara...	1.0E-47	[7..289]	[48..332]
CE18519 - Dual specificity phosphatase, catalytic domain status:Confirmed UniProt:Q9XXK8 protein_id:CAA18771.1	2.0E-47	[12..346]	[1..270]

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Predicted Domain #1

Region A:
Residues: [1-70]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGNANSVDE EVTRILGGIY LGGIRPIIDH RPLGAEFNIT HILSVIKFQV IPEYLIRKGY  60
   61 TLKNIPIDDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	152.980454
Match:	1mkp__
Description:	Mapk phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [71-250]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVTDVLQYFD ETNRFIDQCL FPNEVEYSPR LVDFKKKPQR GAVFAHCQAG LSRSVTFIVA  60
   61 YLMYRYGLSL SMAMHAVKRK KPSVEPNENF MEQLHLFEKM GGDFVDFDNP AYKQWKLKQS 120
  121 IKLDPSGSEL VSNSGMFKDS ESSQDLDKLT EAEKSKVTAV RCKKCRTKLA LSTSFIAHDP 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.0
Match:	1larA_
Description:	RPTP Lar
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [251-364]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSKESSEGHF IKRAANSHRI IDIQESQANC SHFFIEPLKW MQPELQGKQE LEGKFSCPGC  60
   61 SSKVGGYNWK GSRCSCGKWV IPAIHLQTSK VDQFPLQSTA LPNMVNFESE KVNR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits