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View Structure Prediction Details

Protein: TID3
Organism: Saccharomyces cerevisiae
Length: 691 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TID3.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
3.0E-95 [1..690] [1120..1843]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
4.0E-94 [1..690] [1123..1846]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-94 [1..690] [137..860]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
7.0E-94 [1..690] [1121..1844]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
8.0E-94 [1..690] [1122..1845]

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Predicted Domain #1
Region A:
Residues: [1-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSSTSTDQH VLHHMDPHRF TSQIPTATSS QLRRRNSTNQ GLTDMINKSI ARNTISGTGI  60
   61 PTGGINKNKR TRSTVAGGTN GTALALNDKS NSRNSVSRLS INQLGSLQQH LSNRDPRPLR 120
  121 DKNFQSAIQE EIYDYLKKNK FDIETNHPIS IKFLKQPTQK GFIIIFKWLY LRLDPGYGFT 180
  181 K

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 46.431798
Match: PF03801
Description: HEC/Ndc80p family

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [182-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIENEIYQIL KNLRYPFLES INKSQISAVG GSNWHKFLGM LHWMVRTNIK LDMCLNKVDR  60
   61 SLINQNTQEI TILSQPLKTL DEQDQRQERY ELMVEKLLID YFTESYKSFL KLEDNYEPSM 120
  121 QELKLGFEKF VHIINTDIAN LQTQNDNLYE KYQEVMKISQ KIKTTREKWK ALKSDSNKYE 180
  181 NYVNAMKQKS QEWPGKLEKM KSECELKEEE IKALQSNISE LHKILRKKGI STEQFELQNQ 240
  241 EREKLTRELD KINIQSDKLT SSIKSRKLEA EGIFKSLLDT LRQYDSSIQN LTRSRSQLGH 300
  301 NVNDSSLKIN ISENLLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.9794
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [499-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDFHEGISYE QLFPKGSGIN ESIKKSILKL NDEIQERIKT IEKDNITLEK DIKNLKHDIN  60
   61 EKTQINEKLE LELSEANSKF ELSKQEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [586-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERLLVAQRIE IEKMEKKIND SNLLMKTKIS DAEELVTSTE LKLEELKVDL NRKRYKLHQQ  60
   61 VIHVIDITSK FKINIQSSLE NSENELGNVI EELRNLEFET EHNVTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.661 0.554 chromosome segregation a.4.5 "Winged helix" DNA-binding domain
View Download 0.784 0.051 microtubule nucleation a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.851 0.012 microtubule nucleation a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.696 0.006 microtubule nucleation d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.681 0.003 microtubule nucleation c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.657 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.619 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.548 N/A N/A a.74.1 Cyclin-like
View Download 0.538 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.527 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.522 N/A N/A d.212.1 TolA/TonB C-terminal domain
View Download 0.511 N/A N/A a.47.2 t-snare proteins
View Download 0.463 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.461 N/A N/A a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.461 N/A N/A a.24.11 Bacterial GAP domain
View Download 0.448 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.447 N/A N/A a.24.3 Cytochromes
View Download 0.442 N/A N/A a.47.2 t-snare proteins
View Download 0.441 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.434 N/A N/A a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.432 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.426 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.421 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.418 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.405 N/A N/A a.39.1 EF-hand
View Download 0.402 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.367 N/A N/A f.15.1 Small-conductance potassium channel
View Download 0.367 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.363 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.354 N/A N/A i.1.1 Ribosome and ribosomal fragments
View Download 0.353 N/A N/A d.79.1 YjgF-like
View Download 0.352 N/A N/A a.74.1 Cyclin-like
View Download 0.351 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.347 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.324 N/A N/A a.74.1 Cyclin-like
View Download 0.318 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.318 N/A N/A a.7.1 Spectrin repeat
View Download 0.317 N/A N/A a.1.1 Globin-like
View Download 0.313 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.313 N/A N/A a.18.1 T4 endonuclease V
View Download 0.310 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.309 N/A N/A a.7.1 Spectrin repeat
View Download 0.306 N/A N/A d.52.4 YhbC-like, N-terminal domain
View Download 0.305 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.304 N/A N/A a.7.7 BAG domain
View Download 0.304 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.295 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.294 N/A N/A a.46.1 Methionine synthase domain
View Download 0.292 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.286 N/A N/A a.85.1 Hemocyanin, N-terminal domain
View Download 0.284 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.283 N/A N/A a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.281 N/A N/A a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.274 N/A N/A a.144.1 PABC (PABP) domain
View Download 0.269 N/A N/A c.47.1 Thioredoxin-like
View Download 0.267 N/A N/A a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.265 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.259 N/A N/A a.46.1 Methionine synthase domain
View Download 0.253 N/A N/A c.23.1 CheY-like
View Download 0.249 N/A N/A a.24.3 Cytochromes
View Download 0.247 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.247 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.242 N/A N/A a.24.3 Cytochromes
View Download 0.242 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.242 N/A N/A d.88.1 SRF-like
View Download 0.239 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.238 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.234 N/A N/A a.25.1 Ferritin-like
View Download 0.233 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.232 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.228 N/A N/A e.37.1 Bifunctional dehydrogenase/ferrochelatase Met8p, dimerisation and C-terminal domains
View Download 0.228 N/A N/A a.26.1 4-helical cytokines
View Download 0.226 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.216 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.213 N/A N/A a.112.1 Description not found.
View Download 0.211 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.208 N/A N/A a.150.1 Anti-sigma factor AsiA
View Download 0.206 N/A N/A a.4.2 Methylated DNA-protein cysteine methyltransferase, C-terminal domain
View Download 0.205 N/A N/A a.133.1 Phospholipase A2, PLA2

Predicted Domain #5
Region A:
Residues: [607-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLLMKTKISD AEELVTSTEL KLEELKVDLN RKRYKLHQQV IHVIDITSKF KINIQSSLEN  60
   61 SENELGNVIE ELRNLEFETE HNVTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.851 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.784 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.696 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.681 N/A N/A c.47.2 RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View Download 0.661 N/A N/A a.4.5 "Winged helix" DNA-binding domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle