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View Structure Prediction Details

Protein: TID3
Organism: Saccharomyces cerevisiae
Length: 691 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TID3.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
3.0E-95 [1..690] [1120..1843]
gi|9800488, gi|1... - gi|9800488|gb|AAF99315.1|AF272034_1 fast myosin heavy chain isoform 3 [Gallus gallus], gi|165973976|...
4.0E-94 [1..690] [1123..1846]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-94 [1..690] [137..860]
MYH4_RABIT - Myosin-4 OS=Oryctolagus cuniculus GN=MYH4 PE=1 SV=1
7.0E-94 [1..690] [1121..1844]
MYH1 - myosin, heavy chain 1, skeletal muscle, adult
8.0E-94 [1..690] [1122..1845]

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Predicted Domain #1
Region A:
Residues: [1-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSSTSTDQH VLHHMDPHRF TSQIPTATSS QLRRRNSTNQ GLTDMINKSI ARNTISGTGI  60
   61 PTGGINKNKR TRSTVAGGTN GTALALNDKS NSRNSVSRLS INQLGSLQQH LSNRDPRPLR 120
  121 DKNFQSAIQE EIYDYLKKNK FDIETNHPIS IKFLKQPTQK GFIIIFKWLY LRLDPGYGFT 180
  181 K

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 46.431798
Match: PF03801
Description: HEC/Ndc80p family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [182-498]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SIENEIYQIL KNLRYPFLES INKSQISAVG GSNWHKFLGM LHWMVRTNIK LDMCLNKVDR  60
   61 SLINQNTQEI TILSQPLKTL DEQDQRQERY ELMVEKLLID YFTESYKSFL KLEDNYEPSM 120
  121 QELKLGFEKF VHIINTDIAN LQTQNDNLYE KYQEVMKISQ KIKTTREKWK ALKSDSNKYE 180
  181 NYVNAMKQKS QEWPGKLEKM KSECELKEEE IKALQSNISE LHKILRKKGI STEQFELQNQ 240
  241 EREKLTRELD KINIQSDKLT SSIKSRKLEA EGIFKSLLDT LRQYDSSIQN LTRSRSQLGH 300
  301 NVNDSSLKIN ISENLLD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.9794
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [499-585]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDFHEGISYE QLFPKGSGIN ESIKKSILKL NDEIQERIKT IEKDNITLEK DIKNLKHDIN  60
   61 EKTQINEKLE LELSEANSKF ELSKQEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 2tmaA_
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [586-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ERLLVAQRIE IEKMEKKIND SNLLMKTKIS DAEELVTSTE LKLEELKVDL NRKRYKLHQQ  60
   61 VIHVIDITSK FKINIQSSLE NSENELGNVI EELRNLEFET EHNVTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.851 0.012 microtubule nucleation a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain

Predicted Domain #5
Region A:
Residues: [607-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLLMKTKISD AEELVTSTEL KLEELKVDLN RKRYKLHQQV IHVIDITSKF KINIQSSLEN  60
   61 SENELGNVIE ELRNLEFETE HNVTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.851 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle