| Protein: | NUP159 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1460 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP159.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1460] | [1..1460] |
|
|
7.0E-78 | [57..1328] | [1071..2356] |
|
|
2.0E-64 | [149..1278] | [14..1123] |
|
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1.0E-60 | [159..1204] | [16..1041] |
|
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1.0E-58 | [381..1179] | [22..833] |
|
Region A: Residues: [1-132] |
1 11 21 31 41 51
| | | | | |
1 MSSLKDEVPT ETSEDFGFKF LGQKQILPSF NEKLPFASLQ NLDISNSKSL FVAASGSKAV 60
61 VGELQLLRDH ITSDSTPLTF KWEKEIPDVI FVCFHGDQVL VSTRNALYSL DLEELSEFRT 120
121 VTSFEKPVFQ LK
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.370 | c.23.1 | CheY-like |
| View | Download | 0.382 | d.153.1 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) |
| View | Download | 0.419 | b.42.1 | Cytokine |
| View | Download | 0.355 | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.466 | d.153.2 | Hypothetical protein MTH1020 |
| View | Download | 0.345 | b.6.1 | Cupredoxins |
| View | Download | 0.342 | b.60.1 | Lipocalins |
| View | Download | 0.342 | a.1.1 | Globin-like |
| View | Download | 0.332 | d.110.4 | SNARE-like |
| View | Download | 0.322 | c.23.4 | Succinyl-CoA synthetase domains |
| View | Download | 0.290 | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.258 | c.103.1 | Hypothetical protein MT938 (MTH938) |
| View | Download | 0.257 | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.252 | b.61.4 | Quinohemoprotein amine dehydrogenase A chain, domain 3 |
| View | Download | 0.230 | d.97.1 | Cell cycle regulatory proteins |
| View | Download | 0.227 | b.55.1 | PH domain-like |
| View | Download | 0.216 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.212 | c.47.1 | Thioredoxin-like |
| View | Download | 0.209 | c.31.1 | DHS-like NAD/FAD-binding domain |
| View | Download | 0.209 | c.23.6 | Cobalamin (vitamin B12)-binding domain |
| View | Download | 0.206 | b.24.1 | Hyaluronate lyase-like, C-terminal domain |
| Term | Confidence | Notes |
| nucleocytoplasmic transporter activity | 7.36869426424539 | bayes_pls_golite062009 |
| transporter activity | 2.55928656852707 | bayes_pls_golite062009 |
| binding | 1.85720332251545 | bayes_pls_golite062009 |
| structural molecule activity | 1.15400876251633 | bayes_pls_golite062009 |
| protein binding | 0.756333887228113 | bayes_pls_golite062009 |
|
Region A: Residues: [133-609] |
1 11 21 31 41 51
| | | | | |
1 NVNNTLVILN SVNDLSALDL RTKSTKQLAQ NVTSFDVTNS QLAVLLKDRS FQSFAWRNGE 60
61 MEKQFEFSLP SELEELPVEE YSPLSVTILS PQDFLAVFGN VISETDDEVS YDQKMYIIKH 120
121 IDGSASFQET FDITPPFGQI VRFPYMYKVT LSGLIEPDAN VNVLASSCSS EVSIWDSKQV 180
181 IEPSQDSERA VLPISEETDK DTNPIGVAVD VVTSGTILEP CSGVDTIERL PLVYILNNEG 240
241 SLQIVGLFHV AAIKSGHYSI NLESLEHEKS LSPTSEKIPI AGQEQEEKKK NNESSKALSE 300
301 NPFTSANTSG FTFLKTQPAA ANSLQSQSSS TFGAPSFGSS AFKIDLPSVS STSTGVASSE 360
361 QDATDPASAK PVFGKPAFGA IAKEPSTSEY AFGKPSFGAP SFGSGKSSVE SPASGSAFGK 420
421 PSFGTPSFGS GNSSVEPPAS GSAFGKPSFG TPSFGSGNSS AEPPASGSAF GKPSFGT
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [610-935] |
1 11 21 31 41 51
| | | | | |
1 SAFGTASSNE TNSGSIFGKA AFGSSSFAPA NNELFGSNFT ISKPTVDSPK EVDSTSPFPS 60
61 SGDQSEDESK SDVDSSSTPF GTKPNTSTKP KTNAFDFGSS SFGSGFSKAL ESVGSDTTFK 120
121 FGTQASPFSS QLGNKSPFSS FTKDDTENGS LSKGSTSEIN DDNEEHESNG PNVSGNDLTD 180
181 STVEQTSSTR LPETPSDEDG EVVEEEAQKS PIGKLTETIK KSANIDMAGL KNPVFGNHVK 240
241 AKSESPFSAF ATNITKPSST TPAFSFGNST MNKSNTSTVS PMEEADTKET SEKGPITLKS 300
301 VENPFLPAKE ERTGESSKKD HNDDPK
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [936-1376] |
1 11 21 31 41 51
| | | | | |
1 DGYVSGSEIS VRTSESAFDT TANEEIPKSQ DVNNHEKSET DPKYSQHAVV DHDNKSKEMN 60
61 ETSKNNERSG QPNHGVQGDG IALKKDNEKE NFDSNMAIKQ FEDHQSSEED ASEKDSRQSS 120
121 EVKESDDNMS LNSDRDESIS ESYDKLEDIN TDELPHGGEA FKAREVSASA DFDVQTSLED 180
181 NYAESGIQTD LSESSKENEV QTDAIPVKHN STQTVKKEAV DNGLQTEPVE TCNFSVQTFE 240
241 GDENYLAEQC KPKQLKEYYT SAKVSNIPFV SQNSTLRLIE STFQTVEAEF TVLMENIRNM 300
301 DTFFTDQSSI PLVKRTVRSI NNLYTWRIPE AEILLNIQNN IKCEQMQITN ANIQDLKEKV 360
361 TDYVRKDIAQ ITEDVANAKE EYLFLMHFDD ASSGYVKDLS THQFRMQKTL RQKLFDVSAK 420
421 INHTEELLNI LKLFTVKNKR L
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [1377-1460] |
1 11 21 31 41 51
| | | | | |
1 DDNPLVAKLA KESLARDGLL KEIKLLREQV SRLQLEEKGK KASSFDASSS ITKDMKGFKV 60
61 VEVGLAMNTK KQIGDFFKNL NMAK
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.847 | 0.169 | nuclear pore organization | a.65.1 | Annexin |
| View | Download | 0.386 | 0.169 | nuclear pore organization | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.436 | 0.169 | nuclear pore organization | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.457 | 0.169 | nuclear pore organization | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.533 | 0.169 | nuclear pore organization | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.364 | 0.169 | nuclear pore organization | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.317 | 0.169 | nuclear pore organization | c.47.1 | Thioredoxin-like |
| View | Download | 0.313 | 0.169 | nuclear pore organization | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.309 | 0.169 | nuclear pore organization | a.64.1 | Saposin |
| View | Download | 0.307 | 0.169 | nuclear pore organization | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.299 | 0.169 | nuclear pore organization | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.295 | 0.169 | nuclear pore organization | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.294 | 0.169 | nuclear pore organization | a.59.1 | PAH2 domain |
| View | Download | 0.290 | 0.169 | nuclear pore organization | d.29.1 | Ribosomal protein L31e |
| View | Download | 0.286 | 0.169 | nuclear pore organization | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.284 | 0.169 | nuclear pore organization | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.273 | 0.169 | nuclear pore organization | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.258 | 0.169 | nuclear pore organization | d.51.1 | Eukaryotic type KH-domain (KH-domain type I) |
| View | Download | 0.254 | 0.169 | nuclear pore organization | a.21.1 | HMG-box |
| View | Download | 0.253 | 0.169 | nuclear pore organization | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.251 | 0.169 | nuclear pore organization | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.249 | 0.169 | nuclear pore organization | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.249 | 0.169 | nuclear pore organization | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.240 | 0.169 | nuclear pore organization | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.237 | 0.169 | nuclear pore organization | d.228.1 | Replication modulator SeqA, C-terminal DNA-binding domain |
| View | Download | 0.234 | 0.169 | nuclear pore organization | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.229 | 0.169 | nuclear pore organization | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.228 | 0.169 | nuclear pore organization | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.228 | 0.169 | nuclear pore organization | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.226 | 0.169 | nuclear pore organization | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.226 | 0.169 | nuclear pore organization | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.218 | 0.169 | nuclear pore organization | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.216 | 0.169 | nuclear pore organization | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.214 | 0.169 | nuclear pore organization | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.210 | 0.169 | nuclear pore organization | a.77.1 | DEATH domain |
| View | Download | 0.209 | 0.169 | nuclear pore organization | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.205 | 0.169 | nuclear pore organization | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.202 | 0.169 | nuclear pore organization | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.202 | 0.169 | nuclear pore organization | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.201 | 0.169 | nuclear pore organization | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.201 | 0.169 | nuclear pore organization | d.58.11 | EF-G/eEF-2 domains III and V |
