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View Structure Prediction Details

Protein: AIR1
Organism: Saccharomyces cerevisiae
Length: 360 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIR1.

Description E-value Query
Range
Subject
Range
AIR1 - Zinc knuckle protein, involved in nuclear RNA processing and degradation as a component of the TRAMP...
AIR1_YEAST - Protein AIR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AIR1 PE=1 SV=1
gi|151943084 - gi|151943084|gb|EDN61419.1| arginine methyltransferase-interacting ring finger protein [Saccharomyce...
0.0 [1..360] [1..360]
gi|5305478 - gi|5305478|gb|AAD41666.1|AF075702_1 gag protein [Human immunodeficiency virus type 1]
1.0E-97 [20..238] [303..496]

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Predicted Domain #1
Region A:
Residues: [1-99]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLLSEVES IDTLPYVKDT TPTGSDSSSF NKLLAPSIED VDANPEELRT LRGQGRYFGI  60
   61 TDYDSNGAIM EAEPKCNNCS QRGHLKRNCP HVICTYCGF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 35.522879
Match: 1baj__
Description: HIV capsid protein, dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.04588712677166 bayes_pls_golite062009
DNA binding 2.53317408686316 bayes_pls_golite062009
nucleic acid binding 2.33828046499668 bayes_pls_golite062009
binding 2.07015157850093 bayes_pls_golite062009
transcription factor activity 2.0090791129794 bayes_pls_golite062009
transcription activator activity 0.68790059848359 bayes_pls_golite062009
protein binding 0.679430693038119 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [100-168]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDHYSQHCP KAIICTNCNA NGHYKSQCPH KWKKVFCTLC NSKRHSRERC PSIWRSYLLK  60
   61 TKDANQGDF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.69897
Match: 1aaf__
Description: HIV nucleocapsid
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [169-233]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFQTVFCYNC GNAGHFGDDC AERRSSRVPN TDGSAFCGDN LATKFKQHYF NQLKDYKREA  60
   61 SQRQH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.336 a.6.1 Putative DNA-binding domain
View Download 0.336 a.6.1 Putative DNA-binding domain
View Download 0.307 a.2.7 tRNA-binding arm
View Download 0.307 a.2.7 tRNA-binding arm
View Download 0.265 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.265 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.289 d.9.2 Description not found.
View Download 0.289 d.9.2 Description not found.
View Download 0.282 a.6.1 Putative DNA-binding domain
View Download 0.282 a.6.1 Putative DNA-binding domain
View Download 0.249 a.6.1 Putative DNA-binding domain
View Download 0.246 d.120.1 Cytochrome b5
View Download 0.238 c.47.1 Thioredoxin-like
View Download 0.235 a.4.1 Homeodomain-like
View Download 0.231 a.144.1 PABC (PABP) domain
View Download 0.205 a.60.11 Hypothetical protein YjbJ

Predicted Domain #4
Region A:
Residues: [234-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FDNEHEFNLL DYEYNDDAYD LPGSRTYRDK MKWKGKVQST RNKNSSNNRY ESSNNRKKKS  60
   61 PFSAQNYKVT KNKRVQTHPL DFPRSSQNNR TNDYSSQFSY NRDDFPKGPK NKRGRSSSNK 120
  121 SQRNGRY

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle