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View Structure Prediction Details

Protein: AGE2
Organism: Saccharomyces cerevisiae
Length: 298 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AGE2.

Description E-value Query
Range
Subject
Range
AGE2 - ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Netw...
AGE2_YEAST - ADP-ribosylation factor GTPase-activating protein effector protein 2 OS=Saccharomyces cerevisiae (st...
1.0E-67 [1..298] [1..298]
gi|6807591 - gi|6807591|emb|CAB70912.1| hypothetical protein [Homo sapiens]
9.0E-56 [19..275] [4..289]
SMAP1_MOUSE - Stromal membrane-associated protein 1 OS=Mus musculus GN=Smap1 PE=1 SV=1
3.0E-50 [5..280] [15..331]
gi|4225948 - gi|4225948|emb|CAA10736.1| centaurin gamma 1A [Caenorhabditis elegans]
3.0E-47 [11..259] [670..936]

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Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTSVPVKKA LSALLRDPGN SHCADCKAQL HPRWASWSLG VFICIKCAGI HRSLGTHISK  60
   61 VKSVDLDTWK EEHLVKLIQF KNNLRANSYY EATLADELKQ RKITDTSSLQ NFIKNKYEYK 120
  121 KWIGDLSSIE 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 149.37734
Match: 1dcqA_
Description: Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [131-298]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLNDSTEPVL HKPSANHSLP ASNARLDQSS NSLQKTQTQP PSHLLSTSRS NTSLLNLQVS  60
   61 SLSKTTSNTS VTSSATSIGA ANTKTGNRVG EFGQRNDLKK SILSLYSKPS AQTQSQNSFF 120
  121 TSTTPQPCNT PSPFVNTGIT ATNNNSMNSN SSSNISLDDN ELFKNVWS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle