YRC Public Data Repository - Protein Structure Prediction

Protein:	CAP2
Organism:	Saccharomyces cerevisiae
Length:	287 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP2.

Description	E-value	Query Range	Subject Range
gi\|151943125 - gi\|151943125\|gb\|EDN61460.1\| capping protein beta subunit [Saccharomyces cerevisiae YJM789] CAP2 - Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed end... CAPZB_YEAST - F-actin-capping protein subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CAP...	0.0	[1..287]	[1..287]
CAPZB_BOVIN - F-actin-capping protein subunit beta OS=Bos taurus GN=CAPZB PE=1 SV=1	0.0	[2..285]	[31..299]
gi\|78395087, gi\|... - gi\|80479060\|gb\|AAI09242.1\| Capping protein (actin filament) muscle Z-line, beta [Homo sapiens], gi\|8... CAPZB_RAT - F-actin-capping protein subunit beta OS=Rattus norvegicus GN=Capzb PE=1 SV=1 gi\|55586343 - gi\|55586343\|ref\|XP_513162.1\| PREDICTED: similar to capping protein beta subunit, isoform 2 [Pan trog... CAPZB_PONAB - F-actin-capping protein subunit beta OS=Pongo abelii GN=CAPZB PE=2 SV=2 gi\|61355538 - gi\|61355538\|gb\|AAX41150.1\| capping protein muscle Z-line beta [synthetic construct] CAPZB_PONPY - F-actin-capping protein subunit beta - Pongo pygmaeus (Orangutan) gi\|148613359, gi... - gi\|164664456\|ref\|NP_001106915.1\| capping protein (actin filament) muscle Z-line, beta [Sus scrofa], ... gi\|74142535, gi\|... - gi\|74219999\|dbj\|BAE40579.1\| unnamed protein product [Mus musculus], gi\|74142535\|dbj\|BAE33851.1\| unna... IPI:IPI00714725.... - Tax_Id=9913 Isoform Beta-2 of F-actin capping protein subunit beta, Isoform of P79136, Isoform Beta-...	0.0	[1..285]	[1..270]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..285]	[1..270]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[1..287]	[1..286]
gi\|149024410 - gi\|149024410\|gb\|EDL80907.1\| capping protein (actin filament) muscle Z-line, beta, isoform CRA_b [Rat... CAPZB_MOUSE - F-actin-capping protein subunit beta OS=Mus musculus GN=Capzb PE=1 SV=3	0.0	[1..285]	[1..270]
CAPZB_CHICK - F-actin-capping protein subunit beta isoforms 1 and 2 OS=Gallus gallus GN=CAPZB PE=1 SV=3	0.0	[1..285]	[1..270]
FBpp0304020, cpb-PA - The gene capping protein beta is referred to in FlyBase by the symbol Dmel\cpb (CG17158, FBgn0011570... gi\|194123492, gi... - gi\|195350381\|ref\|XP_002041719.1\| GM16827 [Drosophila sechellia], gi\|194123492\|gb\|EDW45535.1\| GM16827... gi\|194173660, gi... - gi\|195470529\|ref\|XP_002087559.1\| GE17670 [Drosophila yakuba], gi\|194173660\|gb\|EDW87271.1\| GE17670 [D... gi\|220956208, gi... - gi\|220956208\|gb\|ACL90647.1\| cpb-PA [synthetic construct], gi\|220946570\|gb\|ACL85828.1\| cpb-PA [synthe... gi\|194854213, gi... - gi\|194854213\|ref\|XP_001968307.1\| GG24802 [Drosophila erecta], gi\|190660174\|gb\|EDV57366.1\| GG24802 [D...	0.0	[1..283]	[1..269]

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Predicted Domain #1

Region A:
Residues: [1-287]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAQFDAAL DLLRRLNPTT LQENLNNLIE LQPNLAQDLL SSVDVPLSTQ KDSADSNREY  60
   61 LCCDYNRDID SFRSPWSNTY YPELSPKDLQ DSPFPSAPLR KLEILANDSF DVYRDLYYEG 120
  121 GISSVYLWDL NEEDFNGHDF AGVVLFKKNQ SDHSNWDSIH VFEVTTSPSS PDSFNYRVTT 180
  181 TIILHLDKTK TDQNSHMMLS GNLTRQTEKD IAIDMSRPLD VIFTSHVANL GSLIEDIESQ 240
  241 MRNLLETVYF EKTRDIFHQT KNAAIASSAE EANKDAQAEV IRGLQSL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	225.267606
Match:	PF01115
Description:	F-actin capping protein, beta subunit

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
actin binding	6.56144513012007	bayes_pls_golite062009
actin filament binding	5.39928513902709	bayes_pls_golite062009
cytoskeletal protein binding	5.10504476256679	bayes_pls_golite062009
binding	2.46279312857752	bayes_pls_golite062009
protein binding	1.31870344025745	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: