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View Structure Prediction Details

Protein: IRR1
Organism: Saccharomyces cerevisiae
Length: 1150 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IRR1.

Description E-value Query
Range
Subject
Range
SCC3_YEAST - Cohesin subunit SCC3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=IRR1 PE=1 SV=1
IRR1 - Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and m...
0.0 [1..1150] [1..1150]
SA3_MOUSE, STAG3... - Cohesin subunit SA-3 OS=Mus musculus GN=Stag3 PE=1 SV=1, (O70576) Cohesin subunit SA-3 (Stromal anti...
0.0 [7..547] [8..516]
STAG3_RAT - Cohesin subunit SA-3 OS=Rattus norvegicus GN=Stag3 PE=2 SV=1
0.0 [7..506] [8..459]
STAG1_XENLA - Cohesin subunit SA-1 OS=Xenopus laevis GN=stag1 PE=1 SV=1
0.0 [37..547] [2..495]
gi|12718255 - gi|12718255|emb|CAC28644.1| related to nuclear protein SA-1 [Neurospora crassa]
0.0 [25..535] [32..520]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [46..606] [10..538]
SA-PA - The gene Stromalin is referred to in FlyBase by the symbol Dmel\SA (CG3423, FBgn0020616). It is a pr...
gi|220956778, gi... - gi|220956778|gb|ACL90932.1| SA-PA [synthetic construct], gi|220947234|gb|ACL86160.1| SA-PA [syntheti...
0.0 [64..546] [57..516]

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Predicted Domain #1
Region A:
Residues: [1-162]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAVRRSTRI RTKSQVIEED YDDEQNTSAQ HVESDKITAK TQHEEEEEQD TGESEESSSE  60
   61 DDYEDQDDDD YVDTATAKRK SRKRKPKSAS NTSSKRQKKK PTSAQKSAVS HAPAYHRSKK 120
  121 DQDQYLEIAK DFQPTELFDI LSTSEDVSIE ELLREWLETY SE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [163-1150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRDKFLQEFI NLLLNCCGSV ARVEDHDVHS NESSNETIGE IQLLFQRQKL HEFYLLISKE  60
   61 NKKRKNFKMG PLYQNFAEFM TKLLEVANDL QLLYVESDED DTQIVTGNLV LDLLTWLSSF 120
  121 SVCKIRCFRY ISTLTLYLFQ DYLTQQAVNL EKNYLAKLSK QLSLEEKKKR PNNKTLEKLE 180
  181 STIAETQGSK VVIDSIIDNI VKLCFVHRYK DVSDLIRSES MLHLSIWIKN YPEYFLKVTF 240
  241 LKYFGWLLSD NSVSVRLQVT KILPHLIIQN HNSKSTDNSA IRQVFERFKT KILEVAIRDV 300
  301 NLDVRIHSIQ VLTEASSLGY LDDSEILIIS SLMFDEEFDP FKTSSFNKRS KFLSTVAKFL 360
  361 ARVIKEKFDE FIKTHEDLPK EVDGLEVGPV VQVGIFIKIL NDSLIYHLKD CAEVDSRTKI 420
  421 RMLTQAAEFL SPYISTHLKT ICNLLISDTE SNELIQKLQN SANNNSDDED VDDEELDITP 480
  481 LFPIDRNSTI LYLNVFHGLC AGANNPKIQT KDSVKEIVLP LFYDLLNAAS IESADILCPL 540
  541 LESFITFSLD DWISIGYETE LKKITDKTIK AFMDSTIGNS KVDMKYDIFA KFIHHIHHFE 600
  601 KKELQEKFLN QIATLKIHLK KFLQEKMDPN NSRDDYKDLT CSLYELYINK LTILGRDYPI 660
  661 EVDEELLQLF LNNFVSRIPI MFQDFDDSTA QEINFKMLVL LATWNLEKWR EIIEKVRDYE 720
  721 NSISKDLRSV WKPIAAIIGR LNTLVISLAA TNETFENINS LFYLKWSACT SLMDIIVAIK 780
  781 IFELKLPADA TTWRYSMSEQ FPFYLHDNAS KVLLKIFLYL ESLFAKQVDV QLERVADEDA 840
  841 NLNDLPETGF FENIETEFLL FTVKLKGLMK LNILDERFAS RVALNKEKLG PLFKKIVDDT 900
  901 IMENPEPNKK NIQKAKSNQT QREKAPLQPN SERETDHANT ENNDPDIPMT IDLEPIEESS 960
  961 QNNSELAPIE EHPTVVDAID NSDEITQD

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 1000.0
Match: PF03365
Description: No description for PF03365 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.81296846555705 bayes_pls_golite062009
protein binding 1.63424405980235 bayes_pls_golite062009
cytoskeletal protein binding 0.66737572008694 bayes_pls_golite062009
nucleic acid binding 0.118461769548431 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [920-1150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INSLFYLKWS ACTSLMDIIV AIKIFELKLP ADATTWRYSM SEQFPFYLHD NASKVLLKIF  60
   61 LYLESLFAKQ VDVQLERVAD EDANLNDLPE TGFFENIETE FLLFTVKLKG LMKLNILDER 120
  121 FASRVALNKE KLGPLFKKIV DDTIMENPEP NKKNIQKAKS NQTQREKAPL QPNSERETDH 180
  181 ANTENNDPDI PMTIDLEPIE ESSQNNSELA PIEEHPTVVD AIDNSDEITQ D

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle