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View Structure Prediction Details

Protein: YIL001W
Organism: Saccharomyces cerevisiae
Length: 513 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIL001W.

Description E-value Query
Range
Subject
Range
gi|190406223 - gi|190406223|gb|EDV09490.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
YIL001W - Putative protein of unknown function; contains a BTB/POZ domain which generally function in protein ...
YIA1_YEAST - Ankyrin repeat-containing protein YIL001W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
5.0E-89 [1..513] [1..513]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-73 [13..512] [6..477]
ABTB1_MOUSE - Ankyrin repeat and BTB/POZ domain-containing protein 1 OS=Mus musculus GN=Abtb1 PE=2 SV=1
6.0E-72 [13..512] [6..477]
BTB3_SCHPO - BTB/POZ domain-containing protein 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=btb3 P...
btb3 - BTB /POZ domain protein Btb3
5.0E-71 [13..511] [56..521]
gi|119599741, gi... - gi|25777626|ref|NP_742025.1| ankyrin repeat and BTB (POZ) domain containing 1 isoform 3 [Homo sapien...
8.0E-64 [47..512] [16..452]
KLHDB_DROYA - Kelch-like protein diablo OS=Drosophila yakuba GN=dbo PE=3 SV=1
KLHDB_DROSE - Kelch-like protein diablo OS=Drosophila sechellia GN=dbo PE=3 SV=1
dbo-PA - The gene diablo is referred to in FlyBase by the symbol Dmel\dbo (CG6224, FBgn0040230). It is a prot...
8.0E-57 [252..494] [50..272]

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Predicted Domain #1
Region A:
Residues: [1-94]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADKLMDKNF EELCYSCRTG DMDNVDRLIS TGVNVNSVDK FDNSPLFLAS LCGHEAVVKL  60
   61 LLQRGAVCDR DRYEGARCIY GALTDTIRDT LLSY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.519517
Match: 1myo__
Description: Myotrophin
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [95-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DISKAVDVKQ PFATHISSMY NDEGFLKRDI TFRVSNGKLF TAHKFLLCAR SEILAEKMVN  60
   61 EWAKHEIVSL EVRPDIFDIF LKFLYLIPIL HQIEPGQYEE LIELSSKFDI ELLPEFLDKA 120
  121 RHT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.506 0.601 cytoplasm a.118.8 TPR-like
View Download 0.390 0.000 cytoplasm a.118.11 Cytochrome c oxidase subunit E
View Download 0.443 N/A N/A a.118.8 TPR-like
View Download 0.324 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.319 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.300 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.298 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.284 N/A N/A a.79.1 Antitermination factor NusB
View Download 0.281 N/A N/A a.118.8 TPR-like
View Download 0.269 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.268 N/A N/A c.30.1 PreATP-grasp domain
View Download 0.254 N/A N/A d.95.2 Homing endonucleases
View Download 0.246 N/A N/A b.60.1 Lipocalins
View Download 0.239 N/A N/A a.118.11 Cytochrome c oxidase subunit E
View Download 0.233 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.233 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.225 N/A N/A d.189.1 PX domain
View Download 0.220 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.203 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases

Predicted Domain #3
Region A:
Residues: [218-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADPTEKSRLM SDYQYKFTEV ARSQLLIFVN NCIFRSTVDL ANSERRVFSL MNCPAYPDVQ  60
   61 LMVKNRNGAI RIYPCHLAVL SRAEYFKVMF TNNFKEKVTY IKAKHVTGKY NSIIPQLTLP 120
  121 NCEFEVAEII LRYLYADNTD IPWMYAVDVL LLADILLEDR LKTIASTIIT QSKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 1buoA_
Description: Promyelocytic leukaemia zinc finger (PLZF) protein BTB domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [392-513]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIQQYNVFDV LYLSWEIGVE RLEQFAAKFI AIHLQELYKD PEIKRAIMLS SQRISLRQET  60
   61 DTIELVDDIR YYLLRKYSFE PDDVELFENQ DDLEYLKQVG YLEYRKDMGM LDNILADLEL 120
  121 DV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.476 0.321 cytoplasm a.40.1 Calponin-homology domain, CH-domain
View Download 0.489 0.276 cytoplasm d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.589 0.066 cytoplasm a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.486 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.442 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.440 N/A N/A a.1.1 Globin-like
View Download 0.439 N/A N/A a.3.1 Cytochrome c
View Download 0.433 N/A N/A a.7.7 BAG domain
View Download 0.430 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.411 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.391 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.375 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.365 N/A N/A a.135.1 Tetraspanin
View Download 0.361 N/A N/A a.47.2 t-snare proteins
View Download 0.350 N/A N/A a.1.1 Globin-like
View Download 0.337 N/A N/A a.118.13 Arp2/3 complex 16 kDa subunit ARPC5
View Download 0.333 N/A N/A a.118.8 TPR-like
View Download 0.332 N/A N/A a.24.4 Hemerythrin
View Download 0.325 N/A N/A a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.318 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.315 N/A N/A a.47.2 t-snare proteins
View Download 0.314 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.301 N/A N/A a.118.8 TPR-like
View Download 0.298 N/A N/A a.1.1 Globin-like
View Download 0.289 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.278 N/A N/A a.77.1 DEATH domain
View Download 0.276 N/A N/A a.26.1 4-helical cytokines
View Download 0.272 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.267 N/A N/A d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.265 N/A N/A a.63.1 Apolipophorin-III
View Download 0.260 N/A N/A a.74.1 Cyclin-like
View Download 0.258 N/A N/A c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.255 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.246 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.239 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.239 N/A N/A a.2.7 tRNA-binding arm
View Download 0.239 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.235 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.235 N/A N/A c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.235 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.233 N/A N/A d.8.1 Urease, gamma-subunit
View Download 0.232 N/A N/A a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.231 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.220 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.220 N/A N/A a.3.1 Cytochrome c
View Download 0.213 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.207 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.206 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.206 N/A N/A a.101.1 Uteroglobin-like
View Download 0.205 N/A N/A d.189.1 PX domain
View Download 0.205 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.202 N/A N/A d.58.26 GHMP Kinase, C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle