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View Structure Prediction Details

Protein: PCL5
Organism: Saccharomyces cerevisiae
Length: 229 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PCL5.

Description E-value Query
Range		 Subject
Range
gi|151944015 - gi|151944015|gb|EDN62308.1| pho85 cyclin [Saccharomyces cerevisiae YJM789]
PCL5 - Cyclin, interacts with and phosphorylated by Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p ...
gi|190405853 - gi|190405853|gb|EDV09120.1| G1/S-specific cyclin PCL5 [Saccharomyces cerevisiae RM11-1a]
gi|207344683 - gi|207344683|gb|EDZ71744.1| YHR071Wp-like protein [Saccharomyces cerevisiae AWRI1631]
PCL5_YEAST - PHO85 cyclin-5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PCL5 PE=1 SV=1
 1.0E-52 [1..229] [1..229]
gi|6331704 - gi|6331704|dbj|BAA86629.1| cyclin [Oryza sativa]
 6.0E-45 [51..229] [155..344]
CCNB2_MEDSV - G2/mitotic-specific cyclin-2 OS=Medicago sativa subsp. varia PE=2 SV=1
gi|7438515 - pir||T09706 cyclin cycMs2, B-type - alfalfa
 7.0E-43 [1..227] [117..362]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 3.0E-42 [59..227] [181..358]
gi|1665741 - gi|1665741|dbj|BAA11560.1| cyclin [Adiantum capillus-veneris]
 2.0E-41 [38..227] [255..432]
gi|1752809 - gi|1752809|dbj|BAA14010.1| cyclin A [Asterina pectinifera]
 3.0E-41 [52..210] [192..351]
CCB23_ARATH - Cyclin-B2-3 OS=Arabidopsis thaliana GN=CYCB2-3 PE=2 SV=2
 7.0E-41 [50..227] [178..363]

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Predicted Domain #1
Region A:
Residues: [1-229] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGNHRFTPD SKEFNTVVKS KESSTGRNPY QTPPLEHNGT HHQTNYSRKK TNLAIIISNF  60
   61 LSEISRPLSN GKINNSTHNI LKFLNEVLKR SKCSKENAVL ATFYFQKIHQ SRGVRDESSL 120
  121 PEFSHCSRRI FLCCLILSHK FLNDNTYSMK NWQIISGLHA KDLSLMERWC LGKLNYELAI 180
  181 PYDEFLLWET NTLMKAKLRV GTPANAPVKR PRESDNDYDA NSWKQIKSC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.39794
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cyclin-dependent protein kinase regulator activity 3.19553060844126 bayes_pls_golite062009
protein kinase regulator activity 2.87088741581791 bayes_pls_golite062009
transcription regulator activity 2.795846725429 bayes_pls_golite062009
cyclin-dependent protein kinase activity 2.6060225603832 bayes_pls_golite062009
binding 2.4204867358489 bayes_pls_golite062009
DNA binding 1.94297811210385 bayes_pls_golite062009
nucleic acid binding 1.74388377119212 bayes_pls_golite062009
kinase regulator activity 1.65109787211976 bayes_pls_golite062009
protein binding 1.47106731485576 bayes_pls_golite062009
transcription factor activity 1.21921365719206 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.09952334871968 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.90568770487799 bayes_pls_golite062009
transcription factor binding 0.749278791251235 bayes_pls_golite062009
enzyme regulator activity 0.729629809946521 bayes_pls_golite062009
transcription activator activity 0.0696060248241566 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle