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View Structure Prediction Details

Protein: COX6
Organism: Saccharomyces cerevisiae
Length: 148 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX6.

Description E-value Query
Range
Subject
Range
gi|123993817 - gi|123993817|gb|ABM84510.1| cytochrome c oxidase subunit Va [synthetic construct]
COX5A - cytochrome c oxidase subunit Va
2.0E-57 [1..143] [1..145]
COX5A_MOUSE, COX... - (P12787) Cytochrome c oxidase polypeptide Va, mitochondrial precursor (EC 1.9.3.1), Cytochrome c oxi...
3.0E-55 [1..143] [1..140]
COX6_YEAST - Cytochrome c oxidase subunit 6, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288...
COX6 - Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane...
gi|190405834 - gi|190405834|gb|EDV09101.1| cytochrome c oxidase subunit [Saccharomyces cerevisiae RM11-1a]
gi|151943997 - gi|151943997|gb|EDN62290.1| cytochrome c oxidase subunit VI [Saccharomyces cerevisiae YJM789]
3.0E-55 [1..148] [1..148]
COX5A_RAT - Cytochrome c oxidase subunit 5A, mitochondrial OS=Rattus norvegicus GN=Cox5a PE=1 SV=1
2.0E-52 [1..143] [1..141]
COX6_SCHPO - Cytochrome c oxidase subunit 6, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)...
cox6 - cytochrome c oxidase subunit VI
3.0E-48 [8..144] [12..139]
COX5A_BOVIN - Cytochrome c oxidase subunit 5A, mitochondrial OS=Bos taurus GN=COX5A PE=1 SV=2
6.0E-48 [42..143] [1..104]
gi|16306441 - gi|16306441|gb|AAL17607.1|AF420467_1 cytochrome c oxidase subunit Va [Rhyzopertha dominica]
2.0E-47 [28..143] [16..134]
cco-2 - status:Confirmed UniProt:P55954 protein_id:CAA21532.1
2.0E-42 [2..143] [4..140]

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Predicted Domain #1
Region A:
Residues: [1-148]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSRAIFRNP VINRTLLRAR PGAYHATRLT KNTFIQSRKY SDAHDEETFE EFTARYEKEF  60
   61 DEAYDLFEVQ RVLNNCFSYD LVPAPAVIEK ALRAARRVND LPTAIRVFEA LKYKVENEDQ 120
  121 YKAYLDELKD VRQELGVPLK EELFPSSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 178.69897
Match: 1occE_
Description: Cytochrome c oxidase subunit E
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytochrome-c oxidase activity 13.5907467824992 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors 13.5907467824992 bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor 13.5907467824992 bayes_pls_golite062009
heme-copper terminal oxidase activity 13.2768834037467 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 7.11269745957917 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 6.95782581983891 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 6.3444074949287 bayes_pls_golite062009
cation transmembrane transporter activity 6.0779545597528 bayes_pls_golite062009
oxidoreductase activity 6.07124287051458 bayes_pls_golite062009
ion transmembrane transporter activity 5.87041225771312 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 5.44223516926039 bayes_pls_golite062009
substrate-specific transporter activity 5.2274118132466 bayes_pls_golite062009
electron carrier activity 1.73787331766336 bayes_pls_golite062009
catalytic activity 1.17990683373825 bayes_pls_golite062009
transporter activity 0.0449232084165001 bayes_pls_golite062009
transmembrane transporter activity 0.0241192035901199 bayes_pls_golite062009

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