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View Structure Prediction Details

Protein: INM1
Organism: Saccharomyces cerevisiae
Length: 295 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for INM1.

Description E-value Query
Range		 Subject
Range
IMPA1_RAT - Inositol monophosphatase 1 OS=Rattus norvegicus GN=Impa1 PE=1 SV=2
 7.0E-74 [1..281] [1..269]
IMPA1 - inositol(myo)-1(or 4)-monophosphatase 1
 9.0E-74 [1..281] [1..269]
IMPA1_BOVIN - Inositol monophosphatase 1 OS=Bos taurus GN=IMPA1 PE=1 SV=1
 1.0E-71 [1..281] [1..269]
INM1 - Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messen...
gi|207344717 - gi|207344717|gb|EDZ71767.1| YHR046Cp-like protein [Saccharomyces cerevisiae AWRI1631]
INM1_YEAST - Inositol monophosphatase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=INM1 PE=1 SV=...
 1.0E-71 [1..295] [1..295]
IMPA1_PIG - Inositol monophosphatase 1 OS=Sus scrofa GN=IMPA1 PE=2 SV=1
 3.0E-71 [1..281] [1..269]
gi|74137533, gi|... - gi|74227685|dbj|BAE35691.1| unnamed protein product [Mus musculus], gi|74220541|dbj|BAE31486.1| unna...
 3.0E-71 [1..281] [1..269]
IMPA1_XENLA - Inositol monophosphatase 1 OS=Xenopus laevis GN=impa1 PE=2 SV=1
 3.0E-69 [1..281] [1..273]

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Predicted Domain #1
Region A:
Residues: [1-149] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIDLASIEK FLCELATEKV GPIIKSKSGT QKDYDLKTGS RSVDIVTAID KQVEKLIWES  60
   61 VKTQYPTFKF IGEESYVKGE TVITDDPTFI IDPIDGTTNF VHDFPFSCTS LGLTVNKEPV 120
  121 VGVIYNPHIN LLVSASKGNG MRVNNKDYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 464.522879
Match: 1imaA_
Description: Inositol monophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatase activity 6.94859134959555 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.73672244222293 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 6.00413152384861 bayes_pls_golite062009
hydrolase activity 4.43275987578288 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 3.57479316466542 bayes_pls_golite062009
inositol-1(or 4)-monophosphatase activity 3.34662957972704 bayes_pls_golite062009
carbohydrate phosphatase activity 2.14796627243145 bayes_pls_golite062009
catalytic activity 2.13229228332707 bayes_pls_golite062009
fructose 1,6-bisphosphate 1-phosphatase activity 1.61382250100271 bayes_pls_golite062009
binding 1.53051725610674 bayes_pls_golite062009
protein binding 0.286223098418614 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-295] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKSKLESMGS LILNKSVVAL QPGSAREGKN FQTKMATYEK LLSCDYGFVH GFRNLGSSAM  60
   61 TMAYIAMGYL DSYWDGGCYS WDVCAGWCIL KEVGGRVVGA NPGEWSIDVD NRTYLAVRGT 120
  121 INNESDEQTK YITDFWNCVD GHLKYD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 464.522879
Match: 1imaA_
Description: Inositol monophosphatase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle