YRC Public Data Repository - Protein Structure Prediction

Protein:	ARD1
Organism:	Saccharomyces cerevisiae
Length:	238 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARD1.

Description	E-value	Query Range	Subject Range
ARD1_YEAST - N-terminal acetyltransferase A complex catalytic subunit ARD1 OS=Saccharomyces cerevisiae (strain AT... gi\|151943955 - gi\|151943955\|gb\|EDN62248.1\| N alpha-acetyltransferase major subunit [Saccharomyces cerevisiae YJM789... ARD1 - Subunit of N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); acetylates many proteins and thu...	1.0E-53	[1..238]	[1..238]
gi\|162459719, gi... - gi\|162459719\|ref\|NP_001105068.1\| silencing group B protein [Zea mays], gi\|14550116\|gb\|AAK67148.1\|AF3...	6.0E-36	[5..201]	[4..159]
gi\|148677471, gi... - gi\|30519923\|ref\|NP_848719.1\| hypothetical protein LOC28062 [Mus musculus], gi\|16507923\|gb\|AAH14770.1... tr\|M0R635\|M0R635_RAT - Protein LOC100909833 OS=Rattus norvegicus GN=LOC100909833 PE=4 SV=1	6.0E-35	[3..203]	[1..160]
CE18023 - status:Confirmed UniProt:O61219 protein_id:AAC04428.1	1.0E-34	[3..223]	[1..180]
Ard1-PA, Ard1-PB... - The gene Arrest defective 1 is referred to in FlyBase by the symbol Dmel\Ard1 (CG11989, FBgn0036064)... gi\|220942712, gi... - gi\|220952948\|gb\|ACL89017.1\| Ard1-PA [synthetic construct], gi\|220942712\|gb\|ACL83899.1\| Ard1-PA [synt... gi\|194118913, gi... - gi\|195326507\|ref\|XP_002029970.1\| GM25199 [Drosophila sechellia], gi\|194118913\|gb\|EDW40956.1\| GM25199... gi\|194196362, gi... - gi\|195589219\|ref\|XP_002084353.1\| GD14230 [Drosophila simulans], gi\|194196362\|gb\|EDX09938.1\| GD14230 ...	8.0E-34	[3..215]	[1..174]
NAA10 - N(alpha)-acetyltransferase 10, NatA catalytic subunit gi\|109132766 - gi\|109132766\|ref\|XP_001089215.1\| PREDICTED: similar to N-acetyltransferase, homolog of S. cerevisiae... HGNC:18704\|MIM:3... - 10, NatA catalytic subunit gi\|117646630, gi... - gi\|117646630\|emb\|CAL37430.1\| hypothetical protein [synthetic construct], gi\|117646470\|emb\|CAL38702.1...	1.0E-33	[3..211]	[1..166]
gi\|18379062, gi\|... - gi\|21536510\|gb\|AAM60842.1\| unknown [Arabidopsis thaliana], gi\|18379062\|ref\|NP_563677.1\| GCN5-related...	2.0E-31	[1..223]	[1..174]

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Predicted Domain #1

Region A:
Residues: [1-238]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPINIRRATI NDIICMQNAN LHNLPENYMM KYYMYHILSW PEASFVATTT TLDCEDSDEQ  60
   61 DENDKLELTL DGTNDGRTIK LDPTYLAPGE KLVGYVLVKM NDDPDQQNEP PNGHITSLSV 120
  121 MRTYRRMGIA ENLMRQALFA LREVHQAEYV SLHVRQSNRA ALHLYRDTLA FEVLSIEKSY 180
  181 YQDGEDAYAM KKVLKLEELQ ISNFTHRRLK ENEEKLEDDL ESDLLEDIIK QGVNDIIV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.221849
Match:	1i1dA_
Description:	Glucosamine-phoshate N-acetyltransferase GNA1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
N-acetyltransferase activity	6.09290029352595	bayes_pls_golite062009
N-acyltransferase activity	6.08913516066746	bayes_pls_golite062009
acetyltransferase activity	5.86411968036951	bayes_pls_golite062009
histone acetyltransferase activity	5.85159161781386	bayes_pls_golite062009
lysine N-acetyltransferase activity	5.85159161781386	bayes_pls_golite062009
acyltransferase activity	4.72881921515185	bayes_pls_golite062009
transferase activity, transferring acyl groups	4.70793039001114	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	4.69837915971204	bayes_pls_golite062009
transferase activity	3.5778020729894	bayes_pls_golite062009
myristoyltransferase activity	3.50779447340192	bayes_pls_golite062009
glycylpeptide N-tetradecanoyltransferase activity	3.50779447340192	bayes_pls_golite062009
	3.43995513266627	bayes_pls_golite062009
catalytic activity	1.97933499002461	bayes_pls_golite062009
binding	1.07749536895426	bayes_pls_golite062009
histone binding	0.582104626133107	bayes_pls_golite062009
nucleic acid binding	0.522132859536345	bayes_pls_golite062009
protein binding	0.098756769132141	bayes_pls_golite062009
transcription regulator activity	0.0766125702622449	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: