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View Structure Prediction Details

Protein: SBP1
Organism: Saccharomyces cerevisiae
Length: 294 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SBP1.

Description E-value Query
Range
Subject
Range
gi|18858617, gi|... - gi|68085524|gb|AAH65965.2| ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D...
4.0E-65 [4..278] [97..366]
IPI:IPI00192584.... - Tax_Id=10116 RNA binding protein HuB
ELAV2_MOUSE - ELAV-like protein 2 OS=Mus musculus GN=Elavl2 PE=2 SV=1
1.0E-64 [4..278] [92..359]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-64 [4..278] [120..388]
ELAVL2 - ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
2.0E-64 [4..278] [92..358]
gi|728726, gi|14... - gi|728726|emb|CAA59430.1| Xel-1 [Xenopus laevis], gi|148236291|ref|NP_001081613.1| elav like 1 [Xeno...
3.0E-64 [4..278] [120..388]

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Predicted Domain #1
Region A:
Residues: [1-150]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAEIEEATN AVNNLSINDS EQQPRAPTHK TVIDPEDTIF IGNVAHECTE DDLKQLFVEE  60
   61 FGDEVSVEIP IKEHTDGHIP ASKHALVKFP TKIDFDNIKE NYDTKVVKDR EIHIKRARTP 120
  121 GQMQRGGFRG RGGFRGRGGF RGGFRGGYRG 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1cvjA_
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mRNA binding 4.52007814408702 bayes_pls_golite062009
nucleic acid binding 4.51665560478175 bayes_pls_golite062009
RNA binding 4.50438526063124 bayes_pls_golite062009
binding 3.64400841800969 bayes_pls_golite062009
structural molecule activity 2.78501986457503 bayes_pls_golite062009
transcription regulator activity 1.7776932219095 bayes_pls_golite062009
DNA binding 1.65208390030564 bayes_pls_golite062009
1.49431666307335 bayes_pls_golite062009
mRNA 5'-UTR binding 1.30855696645617 bayes_pls_golite062009
protein binding 1.12215421354121 bayes_pls_golite062009
transcription repressor activity 0.998305828880243 bayes_pls_golite062009
structure-specific DNA binding 0.950575788044751 bayes_pls_golite062009
single-stranded RNA binding 0.90573796517364 bayes_pls_golite062009
single-stranded DNA binding 0.87797657439186 bayes_pls_golite062009
mRNA 3'-UTR binding 0.824614388276642 bayes_pls_golite062009
transcription factor activity 0.795084003256395 bayes_pls_golite062009
translation repressor activity, nucleic acid binding 0.461000905454505 bayes_pls_golite062009
hydrolase activity 0.389390547875764 bayes_pls_golite062009
translation regulator activity 0.38120065819101 bayes_pls_golite062009
poly-pyrimidine tract binding 0.32812362201346 bayes_pls_golite062009
sequence-specific DNA binding 0.304235325881492 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.128616879457381 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [151-294]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GFRGRGNFRG RGGARGGFNG QKREKIPLDQ MERSKDTLYI NNVPFKATKE EVAEFFGTDA  60
   61 DSISLPMRKM RDQHTGRIFT SDSANRGMAF VTFSGENVDI EAKAEEFKGK VFGDRELTVD 120
  121 VAVIRPENDE EEIEQETGSE EKQE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.0
Match: 1cvjA_
Description: Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle