YRC Public Data Repository - Protein Structure Prediction

Protein:	XKS1
Organism:	Saccharomyces cerevisiae
Length:	600 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for XKS1.

Description	E-value	Query Range	Subject Range
GLPK2_THEMA, GLK... - Glycerol kinase 2 OS=Thermotoga maritima GN=glpK2 PE=3 SV=2, (Q9X1E4) Glycerol kinase 2 (EC 2.7.1.30... GLPK2_THEMA - Glycerol kinase 2 OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=glpK2 ...	0.0	[21..594]	[2..495]
gi\|7434247 - gi\|7434247\|pir\|\|C72254 glycerol kinase - Thermotoga maritima (strain MSB8) gi\|15644181, gi\|... - gi\|4981995\|gb\|AAD36500.1\|AE001795_3 glycerol kinase [Thermotoga maritima MSB8], gi\|15644181\|ref\|NP_2...	0.0	[21..581]	[2..482]
GLPK_CLOPE - Glycerol kinase OS=Clostridium perfringens GN=glpK PE=3 SV=1 GLPK_CLOPE - Glycerol kinase OS=Clostridium perfringens (strain 13 / Type A) GN=glpK PE=3 SV=1 gi\|168205814, gi... - gi\|170662693\|gb\|EDT15376.1\| glycerol kinase [Clostridium perfringens E str. JGS1987], gi\|168205814\|r... gi\|182624319, gi... - gi\|182624319\|ref\|ZP_02952104.1\| glycerol kinase [Clostridium perfringens D str. JGS1721], gi\|1779105...	0.0	[19..593]	[1..497]
GLPK_BACSU - Glycerol kinase OS=Bacillus subtilis GN=glpK PE=1 SV=1 gi\|2633252, gi\|1... - gi\|2633252\|emb\|CAB12757.1\| glycerol kinase [Bacillus subtilis subsp. subtilis str. 168], gi\|16077994...	0.0	[19..593]	[1..496]
GLPK_CLOAB - Glycerol kinase OS=Clostridium acetobutylicum GN=glpK PE=3 SV=1 GLPK_CLOAB - Glycerol kinase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM...	0.0	[19..594]	[1..498]
GLPK_PYRFU - Glycerol kinase OS=Pyrococcus furiosus GN=glpK PE=3 SV=1 GLPK_PYRFU - Glycerol kinase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=glpK PE=3 ...	0.0	[19..595]	[1..488]
GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi GN=glpK PE=3 SV=1 GLPK_PYRAB - Glycerol kinase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=glpK PE=3 SV=1	0.0	[22..595]	[7..491]
GLPK_PYRKO - Glycerol kinase OS=Pyrococcus kodakaraensis GN=glpK PE=1 SV=2 GLPK_THEKO - Glycerol kinase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) GN=glpK PE=1 S...	0.0	[19..595]	[1..490]
gi\|144982459 - gi\|144982459\|gb\|EDJ90025.1\| glycerol kinase [Haemophilus influenzae R3021] gi\|145271495, gi... - gi\|145639448\|ref\|ZP_01795053.1\| glycerol kinase [Haemophilus influenzae PittII], gi\|145271495\|gb\|EDK... gi\|145637622, gi... - gi\|145637622\|ref\|ZP_01793278.1\| glycerol kinase [Haemophilus influenzae PittHH], gi\|145269219\|gb\|EDK... gi\|145631898 - gi\|145631898\|ref\|ZP_01787654.1\| glycerol kinase [Haemophilus influenzae 22.4-21] GLPK_HAEIN - Glycerol kinase OS=Haemophilus influenzae GN=glpK PE=3 SV=2 gi\|42630951 - gi\|42630951\|ref\|ZP_00156489.1\| COG0554: Glycerol kinase [Haemophilus influenzae R2866] GLPK_HAEIN - Glycerol kinase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=glpK PE=3 S... gi\|229811540, gi... - gi\|229845524\|ref\|ZP_04465652.1\| glycerol kinase [Haemophilus influenzae 6P18H1], gi\|229811540\|gb\|EEP...	0.0	[17..598]	[1..503]
GLPK_STAA2 - Glycerol kinase OS=Staphylococcus aureus (strain JH1) GN=glpK PE=3 SV=1 GLPK_STAA9 - Glycerol kinase OS=Staphylococcus aureus (strain JH9) GN=glpK PE=3 SV=1 GLPK_STAA1 - Glycerol kinase OS=Staphylococcus aureus (strain Mu3 / ATCC 700698) GN=glpK PE=3 SV=1 GLPK_STAAN - Glycerol kinase OS=Staphylococcus aureus (strain N315) GN=glpK PE=1 SV=1 gi\|269202916\|ref... - glycerol kinase [Staphylococcus aureus subsp. aureus ED98] gi\|255006086 - gi\|255006086\|ref\|ZP_05144687.2\| glycerol kinase [Staphylococcus aureus subsp. aureus Mu50-omega] GLPK_STAAM - Glycerol kinase OS=Staphylococcus aureus (strain Mu50 / ATCC 700699) GN=glpK PE=3 SV=1 gi\|25287514 - pir\|\|G89904 glycerol kinase [imported] - Staphylococcus aureus (strain N315)	0.0	[19..593]	[1..496]

Back

Predicted Domain #1

Region A:
Residues: [1-297]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCSVIQRQT REVSNTMSLD SYYLGFDLST QQLKCLAINQ DLKIVHSETV EFEKDLPHYH  60
   61 TKKGVYIHGD TIECPVAMWL EALDLVLSKY REAKFPLNKV MAVSGSCQQH GSVYWSSQAE 120
  121 SLLEQLNKKP EKDLLHYVSS VAFARQTAPN WQDHSTAKQC QEFEECIGGP EKMAQLTGSR 180
  181 AHFRFTGPQI LKIAQLEPEA YEKTKTISLV SNFLTSILVG HLVELEEADA CGMNLYDIRE 240
  241 RKFSDELLHL IDSSSKDKTI RQKLMRAPMK NLIAGTICKY FIEKYGFNTN CKVSPMT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	141.0
Match:	1bo5O_
Description:	Glycerol kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	2.33338276303563	bayes_pls_golite062009
hexokinase activity	1.70516840340504	bayes_pls_golite062009
binding	1.44744777288539	bayes_pls_golite062009
glucokinase activity	0.47468456642723	bayes_pls_golite062009
kinase activity	0.345540463799773	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.324655711623803	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.214617425075414	bayes_pls_golite062009
protein binding	0.213044068887966	bayes_pls_golite062009
nucleic acid binding	0.132883501060045	bayes_pls_golite062009
transferase activity	0.105619024604158	bayes_pls_golite062009
glucose binding	0.0361890405625098	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [298-352]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDNLATICSL PLRKNDVLVS LGTSTTVLLV TDKYHPSPNY HLFIHPTLPN HYMGM

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [532-560]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNSCALGGCY KAMWSLLYDS NKIAVPFDK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	141.0
Match:	1bo5O_
Description:	Glycerol kinase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [353-531]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ICYCNGSLAR ERIRDELNKE RENNYEKTND WTLFNQAVLD DSESSENELG VYFPLGEIVP  60
   61 SVKAINKRVI FNPKTGMIER EVAKFKDKRH DAKNIVESQA LSCRVRISPL LSDSNASSQQ 120
  121 RLNEDTIVKF DYDESPLRDY LNKRPERTFF VGGASKNDAI VKKFAQVIGA TKGNFRLET

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [561-600]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FLNDNFPWHV MESISDVDNE NWDRYNSKIV PLSELEKTLI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	141.0
Match:	1bo5O_
Description:	Glycerol kinase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: