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View Structure Prediction Details

Protein: ART5
Organism: Saccharomyces cerevisiae
Length: 586 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ART5.

Description E-value Query
Range
Subject
Range
ART5 - Protein proposed to regulate the endocytosis of plasma membrane proteins by recruiting the ubiquitin...
ART5_YEAST - Arrestin-related trafficking adapter 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=A...
0.0 [1..586] [1..586]
CE09937 - status:Partially_confirmed UniProt:Q9GYT4 protein_id:AAF99937.1
7.0E-89 [143..582] [21..463]
gi|220950140 - gi|220950140|gb|ACL87613.1| CG18745-PA [synthetic construct]
CG18745-PA - This gene is referred to in FlyBase by the symbol Dmel\CG18745 (CG18745, FBgn0042102). It is a prote...
2.0E-71 [156..581] [30..399]
gi|18490372 - gi|18490372|gb|AAH22516.1| Arrestin domain containing 2 [Homo sapiens]
2.0E-70 [157..549] [38..402]

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Predicted Domain #1
Region A:
Residues: [1-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSLSSLSSS GGHSEQKERE RISYFDIRIN SPYKDIILIQ GSPLELSSIP LSGNLVISVK  60
   61 NEIVVKKISL RLVGRFKLEF LQVGRYKKNS SSLASLVKEK RKIFECYWDN LLVSSKGDVL 120
  121 VGGENA

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.356 N/A N/A b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3

Predicted Domain #2
Region A:
Residues: [127-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENQHNSSSGR STSNQDMDTS GNAIFLSKRS LSSPVFNKII RRKTHSSHRK ILELPENGVT  60
   61 GTPFEGLREN ARSRS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.785 a.60.2 RuvA domain 2-like
View Download 0.785 a.60.2 RuvA domain 2-like
View Download 0.736 a.60.2 RuvA domain 2-like
View Download 0.694 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.694 a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.609 d.120.1 Cytochrome b5
View Download 0.609 d.120.1 Cytochrome b5
View Download 0.595 a.39.1 EF-hand
View Download 0.595 a.39.1 EF-hand
View Download 0.586 a.60.11 Hypothetical protein YjbJ
View Download 0.494 a.4.5 "Winged helix" DNA-binding domain
View Download 0.486 a.37.1 A DNA-binding domain in eukaryotic transcription factors
View Download 0.470 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.445 d.15.1 Ubiquitin-like
View Download 0.440 a.156.1 S13-like H2TH domain
View Download 0.393 d.120.1 Cytochrome b5
View Download 0.390 a.77.1 DEATH domain
View Download 0.385 a.77.1 DEATH domain
View Download 0.366 a.39.1 EF-hand
View Download 0.355 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.350 a.64.1 Saposin
View Download 0.339 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.333 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.330 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.321 a.64.2 Bacteriocin AS-48
View Download 0.310 a.144.1 PABC (PABP) domain
View Download 0.295 d.15.1 Ubiquitin-like
View Download 0.294 a.60.1 SAM/Pointed domain
View Download 0.288 a.4.13 Sigma3 and sigma4 domains of RNA polymerase sigma factors
View Download 0.278 a.5.2 UBA-like
View Download 0.278 b.36.1 PDZ domain-like
View Download 0.271 a.77.1 DEATH domain
View Download 0.265 a.4.1 Homeodomain-like
View Download 0.255 a.77.1 DEATH domain
View Download 0.253 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.231 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.226 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.221 a.77.1 DEATH domain
View Download 0.220 a.39.1 EF-hand
View Download 0.214 a.156.1 S13-like H2TH domain

Predicted Domain #3
Region A:
Residues: [202-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSNTLNNNS HSYSNRDGSG SSYLFLMKRG NYELPFNTML PPEVCETIEG LQSGSILYSF  60
   61 EAIIDGRQLW DT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [377-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYYAMKDSSA QIYDDEIA

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [409-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKLDVDCPFT IPDNLKQITQ DCCLQDNLIR VM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1jsyA_
Description: Arrestin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.27724584326272 bayes_pls_golite062009
protein binding 1.04724707449453 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [274-376]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DLSVHTSPHG PIGSTSTSGN GMRTKNKIII KKFKYLRILR TLSMDNLAMQ EEISVGNTWR  60
   61 DKLQYETSIP SRAVPIGSTT PVKIKIFPFE KNIRLDRIEM ALI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [395-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMKITHLADF GPLT

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [441-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HKLQVRILLQ RQVDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.522879
Match: 1jsyA_
Description: Arrestin
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [456-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EYKNLEIKAQ LPMLLFISPH LPMKGRLVLF DKHDGKIHFR PGELVPLFLT TYPAQGLTPG  60
   61 VELNSTTTAH LALPQPPPNY HESTNDHLMP ALQPLGADSV VLTVPSYEQA QAQASASSYV 120
  121 TGSVPAYCDD D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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