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View Structure Prediction Details

Protein: AML1
Organism: Saccharomyces cerevisiae
Length: 248 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AML1.

Description E-value Query
Range
Subject
Range
gi|13940380 - gi|13940380|emb|CAC38017.1| hypothetical protein [Zygosaccharomyces rouxii]
344.0 [0..5] [248..1]

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Predicted Domain #1
Region A:
Residues: [1-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSDSDSDY ELTLSANALA ALEEFKREEQ QHQEAFQKLY DETDEDFQKK KKEEGMKLFK  60
   61 EDWQLSQFWY SDDTAAILAD AILEGADENT VIAIVSAPSV YAAIQKKPTN EIPTEHIYLF 120
  121 EFDKRFELLA GRDHFFFYDY NKPLDFSDEI KGKVDRLLID PPFLNEDCQT KSSITAKCLL 180
  181 APNDNSKTKK GVFKHRLISC TGERMSEVIS KVYSDTRITT FLPEHSNGLS NEFRCYANFE 240
  241 CSSWKFAS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.963
Match: 2fhpA
Description: Crystal Structure of Putative Methylase from Enterococcus faecalis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.16970557486814 bayes_pls_golite062009
transferase activity 0.822796502536128 bayes_pls_golite062009
transcription regulator activity 0.612864078793564 bayes_pls_golite062009
DNA binding 0.590883316793444 bayes_pls_golite062009
nucleic acid binding 0.495242738476094 bayes_pls_golite062009
binding 0.439311894979003 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 0.356820770014331 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.181009652174389 bayes_pls_golite062009
methyltransferase activity 0.165326524526999 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle