YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: MIG2
Organism: Saccharomyces cerevisiae
Length: 382 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIG2.

Description E-value Query
Range
Subject
Range
ZNF287 - zinc finger protein 287
0.0 [2..380] [374..751]
ZSCA2_MOUSE - Zinc finger and SCAN domain-containing protein 2 OS=Mus musculus GN=Zscan2 PE=1 SV=1
0.0 [2..380] [235..612]
ZN252_CANLF - Zinc finger protein 252 OS=Canis lupus familiaris GN=ZNF252 PE=2 SV=1
0.0 [2..380] [413..790]

Back

Predicted Domain #1
Region A:
Residues: [1-66]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKKQTNFPV DNENRPFRCD TCHRGFHRLE HKKRHLRTHT GEKPHHCAFP GCGKSFSRSD  60
   61 ELKRHM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.927757
Match: 2gliA_
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
structure-specific DNA binding 0.790771220986801 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
double-stranded DNA binding 0.53991278722671 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [67-117]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTHTGQSQRR LKKASVQKQE FLTVSGIPTI ASGVMIHQPI PQVLPANMAI N

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.927757
Match: 2gliA_
Description: Five-finger GLI1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [118-202]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VQAVNGGNII HAPNAVHPMV IPIMAQPAPI HASAASFQPA TSPMPISTYT PVPSQSFTSF  60
   61 QSSIGSIQSN SDVSSIFSNM NVRVN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.397 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.408 a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.620 a.130.1 Chorismate mutase II
View Download 0.373 d.45.1 ClpS-like
View Download 0.465 a.24.17 Group V grass pollen allergen
View Download 0.363 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.351 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.349 d.26.1 FKBP-like
View Download 0.347 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.336 d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.333 a.28.1 ACP-like
View Download 0.329 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.325 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.324 a.11.2 Second domain of FERM
View Download 0.322 c.55.7 Methylated DNA-protein cysteine methyltransferase domain
View Download 0.308 b.84.2 Rudiment single hybrid motif
View Download 0.305 d.50.3 PI-Pfui intein middle domain
View Download 0.246 g.39.1 Glucocorticoid receptor-like (DNA-binding domain)
View Download 0.213 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.210 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.204 a.1.1 Globin-like

Predicted functions:

Term Confidence Notes
transcription regulator activity 4.70988788192472 bayes_pls_golite062009
nucleic acid binding 4.58713908116892 bayes_pls_golite062009
DNA binding 4.56219307357342 bayes_pls_golite062009
transcription factor activity 3.50954949535763 bayes_pls_golite062009
transcription repressor activity 3.27542149084008 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.22082323675675 bayes_pls_golite062009
binding 3.10743787485868 bayes_pls_golite062009
transcription activator activity 2.19952417915035 bayes_pls_golite062009
chromatin binding 2.18464662431232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.63161912031789 bayes_pls_golite062009
sequence-specific DNA binding 1.42975942698743 bayes_pls_golite062009
transcription factor binding 1.39608963544799 bayes_pls_golite062009
transcription corepressor activity 1.34049786451995 bayes_pls_golite062009
protein binding 1.00484935878505 bayes_pls_golite062009
structure-specific DNA binding 0.790771220986801 bayes_pls_golite062009
transcription cofactor activity 0.77874411480713 bayes_pls_golite062009
double-stranded DNA binding 0.53991278722671 bayes_pls_golite062009
catalytic activity 0.245893663605433 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [203-255]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPRSVPNSPN DGYLHQQHIP QQYQHQTASP SVAKQQKTFA HSLASALSTL QKR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.68867
Match: 1lu6A_
Description: No description for 1lu6A_ was found.

Predicted Domain #5
Region A:
Residues: [256-382]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TPVSAPSTTI ESPSSPSDSS HTSASSSAIS LPFSNAPSQL AVAKELESVY LDSNRYTTKT  60
   61 RRERAKFEIP EEQEEDTNNS SSGSNEEEHE SLDHESSKSR KKLSGVKLPP VRNLLKQIDV 120
  121 FNGPKRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 128.68867
Match: 1lu6A_
Description: No description for 1lu6A_ was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle