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View Structure Prediction Details

Protein: NUP49
Organism: Saccharomyces cerevisiae
Length: 472 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP49.

Description E-value Query
Range
Subject
Range
NUP49_YEAST - Nucleoporin NUP49/NSP49 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP49 PE=1 SV=1
NUP49 - Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for...
1.0E-51 [1..472] [1..472]
gi|18032249 - gi|18032249|gb|AAL56659.1|AF231130_1 NUP196 nucleoporin [Homo sapiens]
4.0E-42 [2..297] [23..336]
gi|8572547 - gi|8572547|gb|AAB96359.2| high molecular weight outer membrane protein [Moraxella catarrhalis]
3.0E-41 [4..436] [47..545]
gi|6010435 - gi|6010435|gb|AAF01135.1| erythrocyte membrane protein 3 [Plasmodium falciparum]
2.0E-39 [4..328] [1341..1680]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGLNKASST PAGGLFGQAS GASTGNANTG FSFGGTQTGQ NTGPSTGGLF GAKPAGSTGG  60
   61 LGASFGQQQQ QSQTNAFGGS ATTGGGLFGN KPNNTANTGG GLFGANSNSN SGSLFGSNNA 120
  121 QTSRGLFGNN NTNNINNSSS GMNNASAGLF GSKPAGGTSL FGNTSTSSAP AQNQGMFGAK 180
  181 PAGTSLFGNN AGNTTTGGGL FGSKPTGATS LFGSSNNNNN NNNSNNIMSA SGGLFGNQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 1deqA_
Description: Fibrinogen
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [239-390]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQQLQQQPQM QCALQNLSQL PITPMTRISE LPPQIRQEIE QLDQYIQKQV QISHHLKADT  60
   61 IDHDELIDSI PRDVAYLLKS ESATSQYLKQ DLKKISSFKS LIDEDLLDTQ TFSVLLQQLL 120
  121 TPGSKISSND LDKFFQKKIH LYEKKLEDYC RI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [448-472]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TLFMDIAERI AVLHQKTKTL ASLSI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.31
Match: 1dn1B
Description: Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [391-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSDIETAVNG IDTDLFGAPN NPNSTAITAD LGSSEAENLL QLKTGLAAIV STVIEEF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.31
Match: 1dn1B
Description: Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

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