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View Structure Prediction Details

Protein: PTR3
Organism: Saccharomyces cerevisiae
Length: 678 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTR3.

Description E-value Query
Range
Subject
Range
PTR3 - Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses exte...
PTR3_YEAST - SPS-sensor component PTR3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PTR3 PE=1 SV=1
0.0 [1..678] [1..678]

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Predicted Domain #1
Region A:
Residues: [1-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSHRQKWGR QTDIARVLDD IEHDLYLPQR LSLDGATGTD ESHVQYGIVK DCSVLTCGCC  60
   61 ISESLFNDLC RETSNKQTAC PICQRENVRL LSAIKPLRDL ARQIDFFRST TGQGESESDE 120
  121 LPAIVKTSPS SSSLSLTPSR SSSTAGLEAD NKTLSDPTVK EKSSLLELFH IVASKMHNAN 180
  181 TEVGSDHPLT TGTTRDQEEH TTKENYSSSL LEPNYDDHAN WKILDNASNT RTVPIDNNFS 240
  241 LMSTDVTIPS TANYQTNSAH DLDEEKEYFF ANCFPMYRKK FQFNTHPKFL GTKSKLFINQ 300
  301 SISPDCTKFA LITEHKWEIY SINPKDNSPQ LVSCGKSSGE YGPNFNQLTE QSSSSLSTTS 360
  361 QASKKKKKNW SQRFCKLSND FLIISGSQNI LNVHDIHQNG KLIYTYVSRF PIRCIDIDPR 420
  421 SQIIAYGITG KDRHTGAEQA LVVIQQITRN KVTLEPEFPP PITITLPYRD PINTIQLSHD 480
  481 AKYLTCSTAL ESRFLIISLQ KINEPRLIMK SVRSIDTSLE SEGITDTKLF PGNPNLMCIT 540
  541 STAFNSSPLV INTKITQING VRTVAQPSML IRVDEIGCKI HKCEISPRND AIAFLDRNGS 600
  601 VYIMCAPTMM DNNEKRRTIL VETVANAYRA YESATLRFNP EGNKLYILDR KGTFFVEDFA 660
  661 YGLPQSREIT KCKQIFHK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 1.51534322183238 bayes_pls_golite062009
protein binding 1.2335781397975 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [147-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEADNKTLSD PTVKEKSSLL ELFHIVASKM HNANTEVGSD HPLTTGTTRD QEEHTTKENY  60
   61 SSSLLEPNYD DHA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [220-678]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWKILDNASN TRTVPIDNNF SLMSTDVTIP STANYQTNSA HDLDEEKEYF FANCFPMYRK  60
   61 KFQFNTHPKF LGTKSKLFIN QSISPDCTKF ALITEHKWEI YSINPKDNSP QLVSCGKSSG 120
  121 EYGPNFNQLT EQSSSSLSTT SQASKKKKKN WSQRFCKLSN DFLIISGSQN ILNVHDIHQN 180
  181 GKLIYTYVSR FPIRCIDIDP RSQIIAYGIT GKDRHTGAEQ ALVVIQQITR NKVTLEPEFP 240
  241 PPITITLPYR DPINTIQLSH DAKYLTCSTA LESRFLIISL QKINEPRLIM KSVRSIDTSL 300
  301 ESEGITDTKL FPGNPNLMCI TSTAFNSSPL VINTKITQIN GVRTVAQPSM LIRVDEIGCK 360
  361 IHKCEISPRN DAIAFLDRNG SVYIMCAPTM MDNNEKRRTI LVETVANAYR AYESATLRFN 420
  421 PEGNKLYILD RKGTFFVEDF AYGLPQSREI TKCKQIFHK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 1aofA
Description: N-terminal (heme c) domain of cytochrome cd1-nitrite reductase; C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.17860304426104 bayes_pls_golite062009
protein binding 0.0481598093678061 bayes_pls_golite062009
electron carrier activity 0.0445811956513282 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle