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View Structure Prediction Details

Protein: ECO1
Organism: Saccharomyces cerevisiae
Length: 281 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECO1.

Description E-value Query
Range
Subject
Range
ECO1 - Acetytransferase required for sister chromatid cohesion; modifies Smc3p at DNA replication forks dur...
ECO1_YEAST - N-acetyltransferase ECO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ECO1 PE=1 SV=1
0.0 [1..281] [1..281]
gi|15620881 - gi|15620881|dbj|BAB67804.1| KIAA1911 protein [Homo sapiens]
3.0E-76 [14..267] [622..848]
CE27932 - status:Confirmed UniProt:Q19206 protein_id:AAK68308.1
1.0E-73 [2..265] [68..296]
gi|16768922 - gi|16768922|gb|AAL28680.1| LD11462p [Drosophila melanogaster]
1.0E-67 [19..268] [321..527]
gi|2827535, gi|1... - pir||T04507 hypothetical protein F8F16.220 - Arabidopsis thaliana, gi|7270042|emb|CAB79858.1| hypot...
4.0E-59 [11..227] [74..301]
ESO1_SCHPO - N-acetyltransferase eso1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=eso1 PE=1 SV=1
eso1 - sister chromatid cohesion protein Eso1
4.0E-57 [10..261] [635..849]
gi|12845802 - gi|12845802|dbj|BAB26905.1| unnamed protein product [Mus musculus]
4.0E-41 [1..165] [18..147]

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Predicted Domain #1
Region A:
Residues: [1-149]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKARKSQRKA GSKPNLIQSK LQVNNGSKSN KIVKCDKCEM SYSSTSIEDR AIHEKYHTLQ  60
   61 LHGRKWSPNW GSIVYTERNH SRTVHLSRST GTITPLNSSP LKKSSPSITH QEEKIVYVRP 120
  121 DKSNGEVRAM TEIMTLVNNE LNAPHDENV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
N-acetyltransferase activity 6.13726698303784 bayes_pls_golite062009
histone acetyltransferase activity 6.10795007254096 bayes_pls_golite062009
lysine N-acetyltransferase activity 6.10795007254096 bayes_pls_golite062009
N-acyltransferase activity 6.01466152555751 bayes_pls_golite062009
acetyltransferase activity 5.43477850446545 bayes_pls_golite062009
acyltransferase activity 4.18713192358082 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.17218293420277 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 4.15740086660902 bayes_pls_golite062009
3.50745927124371 bayes_pls_golite062009
transferase activity 2.55875279009494 bayes_pls_golite062009
transcription regulator activity 2.00585931208838 bayes_pls_golite062009
nucleic acid binding 1.84222336692632 bayes_pls_golite062009
catalytic activity 1.823104805379 bayes_pls_golite062009
binding 1.30356860355657 bayes_pls_golite062009
histone acetyltransferase activity (H4-K16 specific) 1.29613772727702 bayes_pls_golite062009
transcription factor binding 0.979373407676949 bayes_pls_golite062009
transcription activator activity 0.720181147869432 bayes_pls_golite062009
myristoyltransferase activity 0.333301232703043 bayes_pls_golite062009
glycylpeptide N-tetradecanoyltransferase activity 0.333301232703043 bayes_pls_golite062009
transcription cofactor activity 0.145072909584961 bayes_pls_golite062009
protein binding 0.116359302536336 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [150-281]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IWNSTTEEKG KAFVYIRNDR AVGIIIIENL YGGNGKTSSR GRWMVYDSRR LVQNVYPDFK  60
   61 IGISRIWVCR TARKLGIATK LIDVARENIV YGEVIPRYQV AWSQPTDSGG KLASKYNGIM 120
  121 HKSGKLLLPV YI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.348 0.867 nuclear chromatin b.34.9 Tudor/PWWP/MBT


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle